The diagnosis is based on the following procedure.
Blood tests are not indicated in those with fatty breast enlargement, physiological pubertal or senile changes as identified drug cause or a clinically apparent cancer.
Liver function test
Thyroid function test
Beta hCG level
LH and testosterone low – indicates testicular failure
LH and testosterone both low- indicates increase in estrogen.
LH and testosterone both high- androgen resistance or neoplasm secreting gonadotropins.
Chromosomal karyotyping may be needed.
Ultrasonography or mammography of breasts in all doubtful cases or unilateral breast enlargement is needed.
ultrasonography is indicated if there is a raised beta hCG or AFP
The biopsy is used to indicate and it reveals if any severity arises.