OVERVIEW OF Hepatitis :
Hepatitis is a condition that causes inflammation of the liver. The swelling causes inflammatory responses that may cause elevation in liver enzymes and results in damage to liver. Hepatitis can be an acute or chronic. It can be caused by infection or chemical induced or autoimmune regulated.
Hepatitis is defined as the inflammation of liver parenchyma.
Inflammation is defined as swelling that occurs when tissues of the body are injured or infected.
a.Infectious hepatitis – this type is caused mainly by infections
- More commonly due to hepatitis A, B, C, D, and E
- Rarely due to herpes simplex virus and yellow fever
- Less commonly due to cytomegalovirus, and Epstein Barr virus
b.Radiation hepatitis – radiation weakens immunity thus may result in co infection with other viral infections that may result in inflammation of liver
c.Drug induced hepatitis
d.Alcoholic and non-alcoholic induced hepatitis
f.Autoimmune hepatitis – it is caused in conditions associated with Positive antinuclear antibody and smooth muscle antibody
- Wilsons’s disease
Viral Hepatitis is the most common type of hepatitis. It is most often cause of epidemics. Spread of infection is mainly by the fecal - oral route and due to ingestion of contaminated food or water and sexual interactions.
Drug induced hepatitis has an estimated annual incidence between 15 person every 1,00,000 persons exposed to drugs. Any drug that may be used to treat any condition prescribed or availed over the counter taken over a prolonged period of time or increased dosage may result in inflammation of hepatitis.
Autoimmune diseases cause hepatitis have an incidence rate of 2 person every 1,00,000 people with any autoimmune conditions which may be hereditary or acquired.