Examination of your white blood cells under a microscope.:The bacteria can often be seen inside these white blood cells.Changes in the mononuclear cells is also seen.leucocytopenia can be visualized in response to the bacterial infection.
Peripheral Blood Smear:It shows leucopenia(reduction in the number of white blood cells) and thrombocytopenia(reduction in the number of platelets).
Polymerase chain reaction (PCR): This is a newer method to detect the multiplication of the bacteria and it is used to amplify the bacterial DNA.
Antibody test. This often does not become positive until many days or a few weeks after the infection. It is usually not helpful while you are first sick.
It shows positive for acid fast stain.
Immunohistochemical staining Test: It is used in bone marrow, lymph node and spleen. Immunostaining of bone marrow can also used to detect the presence of the disease.
Indirect Immunofluorescent antibody test: This test detects the antibodies such as IgM developed in response to the Legionellosis. This test shows negative in 1 st week of illness. Hence subsequent serum sample should be collected in further weeks for the detection of antibodies.
CT guided needle Biopsy:
CT scan might be used to guide a biopsy needle into this area to get the tissue for lung and further investigations are made.
It uses the soft tissue image of the organ. It uses the both the magnet and radiowaves and aids in the view of soft tissues of the internal organs.
Immunosorbent assay- detect the specific IgM or IgG antibodies.
Lumbar puncture or spinal tap:
The fluid is drawn from the spinal cord and further investigations are made.
Normal erythrocyte sedimentation problems:
A normal erythrocyte sedimentation rate- it is defined as the rate of red blood cell which are termed as erythrocytes and their deposition or sedimentation rate.
A needle is inserted between the ribs and the sample from pleural fluid is taken.
Urinalysis commonly reveals proteinuria and hematuria.
Fine needle aspiration (FNA) biopsy:
A needle is used to aspirate small fragments of tissues. It is used for cancer in the lymph node in the lungs.
Transtracheal or transbrochial FNA:
It is done by passing the needle through the walls of the trachea or bronchi during bronchoscopy or endobronchial ultrasound.
Transthoracic needle biopsy:
It is used to find out if the tumour is present outside the tumour.
It a procedure that uses a lighted tube inserted behind the sternum (breast bone) and in front of the windpipe to look at and take tissue samples from the lymph nodes along the windpipe and the major bronchial tube areas. If some lymph nodes can’t be reached by mediastinoscopy, a mediastinotomy may be done so the surgeon can directly remove the biopsy sample. For this procedure, a slightly larger incision (usually about 2 inches long) between the left second and third ribs next to the breast bone is needed.
Bronchoscope is a thin lighted instrument used to view the lungs. The physician passes the tube through the trachea then the bronchus and alveoli are viewed clearly.
The chest x ray shows the abnormalities present in the lung.