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INFORMATION ABOUT Erlotinib

Description Erlotinib


Erlotinib is in a class of medication called Tyrosine Kinase inhibitor which is meant for oral use only. It is used in the treatment of non-small cell lung cancer and pancreatic cancer by inhibiting the activity of an abnormal protein that signals the cancer cells to multiply and this helps to stop the growth of cancer cells.

Uses and Benefits of Erlotinib


Erlotinib used in the treatment for the following conditions like

Non-small cancer lung cancer

It is a type of lung cancer. It grows and spreads slowly when compared with small cell lung cancer. Smoking is considered a major risk factor for non-small cancer lung cancer. Symptoms include chronic cough, shortness of breath, chest pain, bone pain, and headache.

Pancreatic cancer

It is a type of cancer that develops when an uncontrolled growth of cells begins in a part of the pancreas. It is usually caused by smoking and diabetes. Symptoms include abdominal pain, loss of appetite, itchy skin, fatigue, blood clots, dark cloured urine.

Mechanism of action of Erlotinib


Erlotinib is a tyrosine kinase inhibitor that produces its action by inhibiting angiogenesis and cellular proliferation.

Contraindications of Erlotinib


It is contraindicated to the patients who are allergic to the composition of the medicines

FAQs for Erlotinib


  • Is the Erlotinib a chemotherapy drug?

No, it is not a chemotherapy drug. It belongs to the class of medication called tyrosine kinase inhibitors which produces its action by inhibiting the activity of an abnormal protein that signals the cancer cells to multiply and this helps to stop the growth of cancer cells.

  • How long can I take the Erlotinib?

You need to take the medicine as per the dose and duration prescribed by your doctor.

  • Does the Erlotinib affect the eyes?

Yes, the common cause of this tablet is conjunctivitis and dry eyes. Immediately seek a doctor if you have experienced eye pain, blurred vision, and light sensitivity.

Driving or operating machinery


It is not known whether it is safe to drive or operate heavy machinery while receiving this medication. Kindly consult with your doctor.

Breast Feeding


It is considered unsafe to use the medicine during breastfeeding it may excrete via breast milk. Kindly consult with your doctor.

Liver Disease


Therapy should be administrated with caution in patients with hepatic impairment. Kindly consult with your doctor.

Use of Medicine in Adult:


It is considered safe if you have taken the medicine as per your doctor's advice. Kindly consult with your doctor.

Use of Erlotinib in Elderly Patients


Limited information is available regarding the use of this medicine in an elderly patient. Kindly consult with your doctor.

Talk to your doctor if


  • If the patient is allergic to the composition of the medicines
  • If you’re using any concomitant medications
  • If you’re not responding to the corresponding treatment

Drug Interaction of Erlotinib

Drug-Drug Interaction


Dexlansoprazole + Erlotinib

The use of this drug is contraindicated because the use of dexlansoprazole decreases the effect of erlotinib by others.

Chloramphenicol + Erlotinib

Therapy should be administered with caution because the use of chloramphenicol will increase the effect of erlotinib by affecting patient hepatic and intestinal enzyme metabolism

Ketoconazole + Erlotinib

Therapy should be administered with caution because the use of ketoconazole will increase the effect of erlotinib by affecting patient hepatic and intestinal enzyme metabolism

Tipranavir + Erlotinib

Therapy should be administered with caution because the use of tipranavir will increase the effect of erlotinib by affecting patient hepatic and intestinal enzyme metabolism

Carbamazepine + Erlotinib

Use alternative drugs because the use of carbamazepine will decrease the effect of erlotinib by affecting patient hepatic and intestinal enzyme metabolism.

Drug-Disease Interaction


GI disorders

Therapy should be administered with caution in patients with gastrointestinal disorders because the use of epidermal growth factor inhibitors is associated with gastrointestinal perforation.

Ocular disorders

Therapy should be administered with caution in patients with ocular disorders such as primary keratitis, ulcerative keratitis, and conjunctivitis.

Pulmonary toxicity

Therapy should be administered with caution in patients with a history of interstitial pneumonia because the use of certain epidermal growth factor inhibitors may cause pulmonary toxicity.

Hepatic and renal impairment

The use of epidermal growth factor inhibitor should be administered with caution in patients with renal and hepatic impairment. During the therapy monitor the patient hepatic functions like transaminases, bilirubin, and alkaline phosphatase.

Over Dose:


Consuming more quantity than the prescribed dose may cause an overdose. Kindly use the medicine as per you’re doctor advice

Storage and Disposal


  • Store the drugs in a closed container at room temperature, and keep the medicines away from heat, moisture, and direct daylight
  • Do not keep the medicine reaching out to children’s
  • Do not keep outdated medicine
  • Ask your doctor or pharmacist the way to eliminate the medicine that’s not in use
  • Store below 30C

Uses of Erlotinib


Erlotinib is used in the treatment of non-small cell lung cancer and pancreatic cancer

Prescribed for Follow Indication


It is used in the treatment of non-small cell lung cancer and pancreatic cancer by inhibiting the activity of an abnormal protein that signals the cancer cells to multiply and this helps to stop the growth of cancer cells.

How to Erlotinib works


Erlotinib is a tyrosine kinase inhibitor that produces its action by inhibiting the activity of an abnormal protein that signals the cancer cells to multiply and this helps to stop the growth of cancer cells.

Side effects of Erlotinib


  • Rash
  • Anorexia
  • Diarrhea
  • Fatigue
  • Infection
  • Conjunctivitis
  • Dry skin
  • Abdominal pain
  • Pulmonary fibrosis
  • Weight loss

Precautions and general warning of Erlotinib

Alcohol


It is not clear whether consuming alcohol may affect the effectiveness of the drug. Kindly consult with your doctor

pregnancy


It is considered unsafe to use the medicine during pregnancy it may produce a harmful effect on the fetus. Kindly consult with your doctor.

Kidney Problem


It is considered safe to use this medicine in patients with renal impairment. Kindly consult with your doctor.

How to Take Medicine


The tablet is taken orally by mouth with or without food. You should not cut, chew or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.

Use of Erlotinib in children:


Information regarding the use of this medicine to the children is not available. Kindly consult with your doctor

General instructions


Erlotinib should be taken at a same time every day. Take this medicine as per your doctor prescription. Do not take the medicine without consulting with the doctor. Follow the dose and duration as per the doctor’s advice do not consume more or less dose than prescribed by the doctor.

Drug-Food Interaction


Erlotinib should be taken on an empty stomach one hour before the meal or 2 hours after the meal. You should also avoid grapefruit juice while you are receiving this medicine it may increase the erlotinib in blood levels.

Missed Dose


If you missed the dose take the medicine as soon as you remember. If it is time for a subsequent dose skip the missed dose and continue with a daily dose

Fast Tag


  • Erlotinib is in a class of medication called a tyrosine kinase inhibitor
  • The drug is employed along with other medications in the treatment of non-small lung cell cancer and pancreatic cancer
  • The tablet is taken orally by mouth with or without food
  • Do not use this medicine if the patient is allergic to the composition of the medicine

AVAILABLE MEDICINE FOR Erlotinib

Birlotib 100 Tablet 100mg

Rs.752.00 Rs.800.00

Birlotib 100mg Tablet 100mg

Rs.640.00 Rs.800.00

Birlotib 150mg Tablet 150mg

Rs.713.43 Rs.891.79

Eltropag 50mg Tablet 50mg

Rs.1905.75 Rs.2250.00

Erloshil 150mg Tablet 150mg

Rs.2279.14 Rs.2848.93

Erlotib 150mg Tablet 150mg

Rs.2380.19 Rs.2975.24

Erlotad 150 Tablet 150mg

Rs.2756.32 Rs.2996.00

Zyceva 100mg Tablet 100mg

Rs.2516.00 Rs.3145.00

Zyceva 150mg Tablet 150mg

Rs.2928.00 Rs.3660.00

Etbmed 100mg Tablet 100mg

Rs.3722.40 Rs.3960.00


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