Adriamycin 50mg Injection

Brand Name Adriamycin 50mg Injection
Salt Composition Doxorubicin (50mg)
Strength 50mg
Product Form Injection
Pack 1 Injection in 1 Vial
Category Anti-Cancer
Country of Origin India
Manufacturer Pfizer India - Chennai Regional Office
Manufacturer/Marketer AddressPfizer India - Chennai Regional Office,MIV Complex 391/392 Anna Salai, Saidapet, Chennai 600 015, Tamil Nadu, India
-20%
Adriamycin 50mg Injection, Doxorubicin 50mg Injection, Price, Uses, Side effects – Drugcarts watermark
M.R.P : Rs.874.39       Price : Rs.699.51

You Save : Rs.174.88    Inclusive of all taxes

- +
1 Injection in 1 Vial

Availability : In Stock


    Medical Description of Adriamycin 50mg Injection

    Adriamycin 50mg Injection contains Doxorubicin 50mg used to treat any type of cancer of the blood, ovaries, lungs, and soft tissue. It works by inhibiting the growth and multiplication of cancer cells by suppressing the enzyme which is involved in the DNA multiplication of cancer cells. It is used alone or with other medication as chemotherapy


    Adriamycin 50mg Injection Uses

    It is used in the treatment of the following conditions as ovary, prostate, breast, stomach, thyroid, liver cancers, small cell lung cancer, squamous cell cancer of head and neck, multiple myeloma, Hodgkin and non- Hodgkin lymphoma, acute lymphocytic leukemia, acute myeloid leukemia.


    Adriamycin 50mg Injection Benefits

    Breast cancer

    It is a type of cancer that forms in the breast cells. It is common among women. Symptoms include breast lump, change in breast size, redness, pitting of the skin, color change, and peeling surrounding the breast skin or nipple. This medicine helps to inhibit the multiplication of cancer cells.

    Ovarian cancer

    It is a type of cancer that occurs in an ovary a female reproductive system that produces women’s eggs and female hormones. The exact is not clear but if you have a history of ovarian cancer in your family. Symptoms include abdominal bloating, weight loss, discomfort in the pelvic area, fatigue, back pain, constipation, and frequent urination. This medicine helps to inhibit the multiplication of cancer cells.

    Prostate cancer

    It is cancer that occurs in a man’s prostate. Usually, it grows slowly and is confined to the prostate gland. Symptoms include difficulty in urinating, blood in urine, semen, bone pain, weight loss, and erectile dysfunction. This medicine helps to inhibit the multiplication of cancer cells.

    Small cell lung cancer

    It is fast-growing cancer that occurs in the tissue of the lung and spreads to other parts of the body. The cause for this cancer is tobacco smoking. Symptoms include bloody mucus, shortness of breath, chest pain, loss of appetite, fatigue, weight loss, and facial swelling.

    Thyroid cancer

    Abnormal cell growth in the thyroid gland leads to the formation of tumor and cause cancer. Symptoms include a lump on your neck, change in your voice, pain in your neck and throat, inflamed lymph nodes in your neck, and difficulty in swallowing.

    Hepatocellular carcinoma

    It is also called malignant hepatoma, it is a common type of liver cancer. It usually occurs in people who are having a chronic liver disease such as cirrhosis, hepatitis B or C. Symptoms include weight loss, inflamed liver, loss of appetite, stomach pain, and jaundice

    Stomach cancer

    It is an abnormal growth of cells that starts in the stomach. Stomach cancer is also called gastric cancer it will affect any part of your stomach. Symptoms include difficulty in swallowing, bloating, heartburn, indigestion, stomach pain, weight loss, and vomiting. This medicine helps to inhibit the multiplication of cancer cells.

    Carcinoma of head and neck

    It is also called throat cancer. Alcohol and Smoking are considered major risk factors for head and neck cancer. Symptoms include swelling in the jaw, lump, trouble in speaking and breathing, pain in ears, headache, nose bleeding, and pain in the upper teeth. This medicine helps to inhibit the multiplication of cancer cells.

    Multiple myeloma

    It is also called Kahler’s disease. It is a type of cancer that occurs in a plasma cell. In this condition, cancer gets accumulated in the bone marrow and affects healthy blood cells. Symptoms include constipation, loss of appetite, fatigue, bone pain, weight loss, frequent infections, excessive thirst, and numbness in your legs.

    Non-Hodgkins leukemia

    It is also known as Non-Hodgkin’s disease, cancer in part of your immune system called the lymphatic system. It occurs when there is a change in the DNA of white blood cells called B lymphocytes. Symptoms include fever, night sweats, weight loss, severe itching, increased sensitivity, and swelling of lymph nodes.

    Hodgkin’s lymphoma

    It is also known as Hodgkin’s disease, cancer in part of your immune system called the lymphatic system. It occurs when there is a change in the DNA of white blood cells called B lymphocytes. Symptoms include fever, night sweats, weight loss, severe itching, increased sensitivity, and swelling of lymph nodes.

    Chronic lymphatic leukemia

    It is a type of blood and bone marrow cancer. The exact cause is unknown but it is assumed that some changes happen in the DNA of blood-producing cells. It progresses more slowly when compared with other leukemia. Symptoms include inflamed lymph nodes, fever, night sweats, weight loss, enlarged spleen, fatigue, and frequent infections.

    Acute Lymphoblastic Leukemia

    It is a type of blood and bone marrow cancer that affects white blood cells in your body. It occurs when a cell in bone marrow develops changes in DNA. Symptoms include frequent infection, pale skin, shortness of breath, fatigue, bleeding from gums, nosebleeds, and bone pain.

    Acute Myeloid Leukemia

    It is also called acute myelogenous leukemia. This cancer occurs in the bone marrow and causes an increase in white blood cells. It occurs due to genetic changes in the stem cells which are produced by the bone marrow. Symptoms include easy bleeding, fever, weight loss, loss of appetite, night sweats, fatigue, and bone pain.


    Adriamycin 50mg Injection Indication

    The Adriamycin 50mg Injection is prescribed in the following indications as ovary, prostate, breast, stomach, thyroid, liver cancers, small cell lung cancer, squamous cell cancer of head and neck, multiple myeloma, Hodgkin and non- Hodgkin lymphoma, acute lymphocytic leukemia, acute myeloid leukemia.


    Mechanism of action of Adriamycin 50mg Injection

    Adriamycin 50mg Injection contains Doxorubicin 50mg is an anti-cancer medication, an anthracycline produces its action by inhibiting DNA and RNA replication by acting on DNA topoisomerase 2 that intercalates DNA base pairs. Thus, causes the formation of an impaired DNA sequence containing abnormal cells where apoptosis occurs and results in cell death.


    How Adriamycin 50mg Injection works

    Adriamycin 50mg Injection contains Doxorubicin 50mg is an anti-cancer medication, an anthracycline produces its action by inhibiting the function of DNA topoisomerase 2 enzymes. This causes impairment in DNA intercalation inducing apoptosis of these abnormal cancer cells. Thus, it treats breast cancer and other cancers.


    Adriamycin 50mg Injection Contraindication

    • Do not take this medicine if you are allergic to Doxorubicin
    • It is contraindicated to use this medicine in patients who are with active infection, severe hepatic impairment, recent myocardial infarction, cardiomyopathy, congestive heart failure, and impaired cardiac function
    • Kindly avoid taking this medicine if your baseline neutrophil count is less than 1500/mm3


    Adriamycin 50mg Injection Side Effects

    • Neutropenia
    • Anemia
    • Stomatitis
    • Fatigue
    • Thrombocytopenia
    • Vomiting
    • Hair loss
    • Constipation
    • Diarrhea
    • Rash


    FAQs for Adriamycin 50mg Injection

    • I am experiencing nausea and fatigue. Is this due to Adriamycin 50mg Injection?

    Yes, the common side effect of this medicine is nausea and fatigue so it is better to eat more frequent meals to decrease nausea and also avoid foods that are salty, spicy, fatty. Drink plenty of rest and do light exercise to keep yourself active

    • Does Adriamycin 50mg Injection cause hair loss?

    Yes, one of the common side effects of this medicine is hair loss. This will get treated once you stop the treatment.

    • I have noticed some changes in my skin after taking the Adriamycin 50mg Injection? What should I do?

    Use sunscreen whenever you step outdoors and use moisturizer to get relief from the rash, dry and itchy skin. Your skin will return to normal once your treatment is stopped.


    Precautions and general warning of Adriamycin 50mg Injection

    Alcohol

    It is not clear whether it is safe to consume alcohol is safe while you are receiving this medicine. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor

    Kidney Problem

    It is considered safe to use this medicine in patients who are with renal impairment. Kindly consult with your doctor.

    Liver Disease

    Therapy should be administered with caution in patients with hepatic impairment. Kindly adjust the dose if it is necessary. Kindly consult with your doctor.


    How to Take Adriamycin 50mg Injection

    Adriamycin 50mg Injection comes in a liquid solution as an intravenous. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Adriamycin 50mg Injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.


    Use of Adriamycin 50mg Injection in children

    It is considered safe to use this medicine in children. Kindly consult with your doctor.


    Use of Adriamycin 50mg Injection in Elderly Patients

    Adriamycin 50mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The use of this medicine may cause irritant
    • The use of this medicine increases the risk of developing secondary acute myelogenous leukemia and myelodysplastic syndrome
    • The clearance of doxorubicin is decreased in patients who are with increased serum bilirubin with increased toxicity
    • Therapy should be administered with caution in elderly and hepatic impairment patients
    • The use of this medicine may cause myelosuppression and increase the radiation-induced toxicity to the myocardium


    Talk to your doctor if

    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have a receiving any concomitant medication and disease


    General instructions

    Doxorubicin 50mg is used to treat ovary, prostate, breast, stomach, thyroid, liver cancers, small cell lung cancer, squamous cell cancer of head and neck, multiple myeloma, Hodgkin and non- Hodgkin lymphoma, acute lymphocytic leukemia, acute myeloid leukemia. It produces its action by inhibiting the function of the DNA topoisomerase 2 enzymes. This causes impairment in DNA intercalation inducing apoptosis of these abnormal cancer cells.


    Drug Interaction of Adriamycin 50mg Injection

    Drug-Drug Interaction

    Chloramphenicol

    Use alternative drugs because the use of chloramphenicol will increase the effect of doxorubicin by affecting its hepatic and intestinal enzyme metabolism.

    Deferiprone

    Use alternative drug because the combination of this medicine either increases the toxicity of the other by pharmacodynamic synergism

    Amiodarone

    Therapy should be administered with caution because the use of amiodarone will increase the effect of doxorubicin by P-glycoprotein efflux transporter

    Cyclophosphamide

    Therapy should be administered with caution because the use of doxorubicin increases the toxicity of the cyclophosphamide by unspecified interaction mechanism and it also increases the risk for developing hemorrhagic cystitis

    Digoxin

    Therapy should be administered with caution because the use of doxorubicin decrease the effect of digoxin by inhibiting GI absorption

    Paclitaxel

    Therapy should be administered with caution because the use of paclitaxel increases the effect of doxorubicin by decreasing its renal clearance.

    Drug-Food Interaction

    No data available kindly consult with your doctor

    Drug-Disease Interaction

    Infections

    The use of this medicine may cause severe infections to include urinary tract infections, pneumonia, sepsis, herpes encephalitis, and mycobacterial infection which lead to retroperitoneal hemorrhage.

    Cardiomyopathy

    The use of this medicine is contraindicated to use this medicine in patients with severe myocardial insufficiency and recent myocardial infarction because the use of this medicine may cause myocardial damage including acute left ventricular failure

    Hepatic dysfunction

    Therapy should be administered with caution in patients with mild to moderate hepatic impairment because the doxorubicin is metabolized by the liver. It is contraindicated to use this medicine in severe hepatic impairment patients

    Myelosuppression

    Therapy should be administered with extreme caution in patients with bone marrow suppression because the use of this medicine induces dose-related myelosuppression


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.

     


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 2-8°C in the refrigerator.
    • Do not freeze
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • ubicin 50mg is an anti-cancer medication, an anthracycline
    • It is used to treat ovary, prostate, breast, stomach, thyroid, liver cancers, small cell lung cancer, squamous cell cancer of head and neck, multiple myeloma, Hodgkin and non- Hodgkin lymphoma, acute lymphocytic leukemia, acute myeloid leukemia.
    • Do not withdraw the medicine without consulting with a doctor
    • Kindly avoid pregnancy while you are receiving this medicine
    • Kindly consult with your doctor if you have experienced shortness of breath, chest pain, loss of appetite, and dark urine while you are receiving this medicine