AFZETA 40MG TABLET

Brand Name AFZETA 40MG TABLET
Salt Composition

Afatinib (40mg)

Strength 40mg
Product Form Tablet
Pack 30 Tablet(s) in Bottle
Storage Store below 30°C
Category

Anti-Cancer

SubCategory

Lung Cancer

Country of Origin India
Manufacturer

Sun Pharmaceutical Industries Limited

Manufacturer/Marketer Address Sun Pharmaceutical Industries Limited Acme Plaza, Andheri Kurla Road, Andheri (East), Mumbai, 400059 India
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M.R.P : Rs.5910.00       Price : Rs.4993.95

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30 Tablet(s) in Bottle

Availability : In Stock

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    Medical Description of AFZETA 40MG TABLET

    Afzeta 40mg Tablet contains Afatinib 40mg used to treat non-small cell lung cancer. It is a first-line therapy to prevent the growth of cancer cells. This medication is recommended only for adults who have a mutation of the epidermal growth factor receptor.


    AFZETA 40MG TABLET Uses

    It is used in the treatment of the following conditions as non-small cell lung cancer


    AFZETA 40MG TABLET Benefits

    Non-small cancer lung cancer

    It is a type of lung cancer. It grows and spreads slowly when compared with small cell lung cancer. Smoking is considered a major risk factor for non-small cancer lung cancer. Symptoms include chronic cough, shortness of breath, chest pain, bone pain, and headache.


    AFZETA 40MG TABLET Indication

    The Afzeta 40mg Tablet is prescribed in the following indications as non-small cell lung cancer.


    Mechanism of action of AFZETA 40MG TABLET

    Afzeta 40mg Tablet contains Afatinib 40mg is an anti-cancer medication, tyrosine kinase inhibitor. It produces its effect by inhibiting the epithelial growth factor receptors and HER2 and 4 which is responsible for the growth of cancer cells, thus the signaling process for angiogenesis and proliferation of abnormal cells is inhibited. This results in minimizing the growth of abnormal cancer cells and terminates metastasis of tumors or cancers


    How AFZETA 40MG TABLET works

    Afzeta 40mg Tablet contains Afatinib 40mg is an anti-cancer medication, tyrosine kinase inhibitor. It produces its effect by inhibiting the epithelial growth factor receptors and HER2 and 4 which is responsible for the growth of cancer cells, thus the signaling process for angiogenesis and proliferation of abnormal cells is inhibited. This results in minimizing the growth of abnormal cancer cells and terminating metastasis of tumors or cancers


    AFZETA 40MG TABLET Contraindication

    Do not take this medicine if you are allergic to Afatinib


    AFZETA 40MG TABLET Side Effects

    • Rash
    • Anorexia
    • Diarrhea
    • Stomatitis
    • Increased ALT
    • Decreased creatinine clearance
    • Increased alkaline phosphate
    • Decreased lymphocytes
    • Dry skin
    • Epistaxis
    • Cystitis


    FAQs for AFZETA 40MG TABLET

    • When can I plan a pregnancy if I am taking an Afzeta 40mg Tablet?

    Avoid planning for pregnancy while you are receiving this medicine and also use an effective contraceptive for at least 1 month after taking the last medicine.

    • Does Afzeta 40mg Tablet affect fertility?

    Yes, the use of this medicine may affect fertility in males as well as in females. Kindly consult with your doctor before initiating the treatment to preserve fertility.

    • How should I manage diarrhea while taking the Afzeta 40mg Tablet?

    If you are suffering from diarrhea drink plenty of fluids like water, sports drink, or clear liquids. You should eat low-fat, high protein-rich foods instead of fatty and spicy foods. Kindly avoid consuming milk and milk products.


    Precautions and general warning of AFZETA 40MG TABLET

    Alcohol

    The use of alcohol does not produce harmful effects while you are receiving this treatment. Kindly consult with your doctor.

    Driving or operating machinery

    It is not clear that the use of this medicine will affect the ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor

    Kidney Problem

    It is considered safe to use this medicine in patients who are having a renal impairment. Kindly consult with your doctor.

    Liver Disease

    It is considered safe to use this medicine in patients who are having a hepatic impairment. Kindly consult with your doctor.


    How to Take AFZETA 40MG TABLET

    Afzeta 40mg Tablet is taken orally with or without food. You should not chew, cut or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of AFZETA 40MG TABLET in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor


    Use of AFZETA 40MG TABLET in children

    Safety and efficacy were not established in children who are below 18 years old. Kindly consult with your doctor.


    Use of AFZETA 40MG TABLET in Elderly Patients

    Afzeta 40mg Tablet should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The use of this medicine may cause diarrhea that results in dehydration with or without renal dysfunctions
    • Therapy should be administered with caution because the medicine may increase the risk of developing phototoxicity
    • Interstitial lung diseases, hepatotoxicity, and GI perforation were reported while using this medicine
    • Keratitis, eye inflammation, lacrimation, light sensitivity, blurred vision, eye pain, and red eye were reported


    Talk to your doctor if

    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have a receiving any concomitant medication and disease


    General instructions

    Afatinib 40mg is used to treat non-small cell lung cancer. Afatinib 40mg is an anti-cancer medication, tyrosine kinase inhibitor. It produces its effect by inhibiting the epithelial growth factor receptors and HER2 and 4 which is responsible for the growth of cancer cells, thus the signaling process for angiogenesis and proliferation of abnormal cells is inhibited. This results in minimizing the growth of abnormal cancer cells and terminates metastasis of tumors or cancers.


    Drug Interaction of AFZETA 40MG TABLET

    Drug-Drug Interaction

    Amiodarone

    Use alternative drugs because the use of amiodarone increases the effect of P-glycoprotein efflux transporter

    Cholera vaccine

    Therapy should be administered with caution because the use of afatinib decreases the effect of the cholera vaccine by immunosuppressive effects and it also increases the risk of developing infections

    Dichlorphenamide

    Therapy should be administered with caution because the combination of this medicine decreases serum potassium level

    Drug-Food Interaction

    Afatinib 40mg should be taken on an empty stomach one hour before the meal or 2 hours after the meal. You should also avoid grapefruit juice while you are receiving this medicine it may increase the Afatinib in blood levels.

    Drug-Disease Interaction

    Lung toxicity

    Therapy should be administered with caution in patients with a history of interstitial pneumonitis, and pulmonary fibrosis because the use of multikinase inhibitors is associated with pulmonary toxicity.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • Afzeta 40mg Tablet contains Afatinib 40mg used to treat non-small cell lung cancer. It is a first-line therapy to prevent the growth of cancer cells. This medication is recommended only for adults who have a mutation of the epidermal growth factor receptor.
    • Take this medicine 1 hour before or 2 hours after your meal
    • The use of this medicine can make your skin sensitive so apply sunscreen and wear protective clothing
    • Kindly inform your doctor if you have experienced headache, stomach pain, and blood in your stool and urine while you are receiving this medicine.