Arsenox 1mg Injection
Brand Name | Arsenox 1mg Injection |
Salt Composition |
Arsenic Trioxide (1mg) |
Strength | 1mg |
Product Form | Injection |
Pack | 1 x 10ml in 1 Vial |
Storage | Store below 30°C |
Category |
Anti-Cancer |
SubCategory |
Blood Cancer |
Country of Origin | India |
Manufacturer |
Intas Pharmaceuticals Ltd |
Manufacturer/Marketer Address | Intas Pharmaceuticals Ltd,Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India. |
- Nausea
- Cough
- Fatigue
- Abdominal pain
- Tachycardia
- Diarrhea
- Hypokalemia
- Hyperglycemia
- Sore throat
- Dermatitis
- Hypotension
- Dizziness
- Is Arsenox 1mg Injection safe?
- I am experiencing nausea and fatigue. Is this due to Arsenox 1mg Injection?
- I have noticed some changes in my skin after taking the Arsenox 1mg Injection? What should I do?
- Differentiation syndrome includes fever, acute respiratory distress, pulmonary infiltrates, pericardial effusions, weight gain, hypotension, and renal dysfunction was reported
- Therapy should be administered with caution in patients with hepatic and renal dysfunction because limited information is available
- Kindly avoid this medicine if you are pregnant because the use of this medicine may cause fetal harm
- Cardiac conduction abnormalities were reported
- Serious encephalopathy including Wernicke’s was reported
- You are not responding to the treatment
- You have experienced any allergic reaction like rashes and itching
- You have a receiving any concomitant medication and disease
- You develop shortness of breath
- Stored at 30°C at room temperature.
- Protect from light and heat.
- Keep away from children and pets. Otherwise, it becomes toxic to them.
- Disposed of properly in a suitable bag.
- Arsenic Trioxide 1mg is an anti-cancer medication, an apoptosis inducer
- It is used to treat acute promyelocytic leukemia
- Kindly monitor the level of calcium, potassium, and creatinine in the blood.
- Do not withdraw the medicine without consulting with a doctor
- Use non-hormonal methods of contraception to avoid pregnancy because the use of this medicine may cause fetal harm
Medical Description of Arsenox 1mg Injection
Arsenox 1mg Injection contains Arsenic Trioxide 1mg used to treat acute promyelocytic leukemia. It works by inhibiting the growth of cancer cells by altering the DNA of abnormal cells. It is used in patients who are not responded to other treatments and it is also used or in combinations with other medicine as first-line treatment.
Arsenox 1mg Injection Uses
It is used in the treatment of the following conditions as acute promyelocytic leukemia.
Arsenox 1mg Injection Benefits
Acute promyelocytic leukemia
It is an aggressive type of acute myeloid leukemia. This cancer occurs in the bone marrow and causes an increase in white blood cells. It occurs due to genetic changes in the stem cells which are produced by the bone marrow. Symptoms include easy bleeding, fever, weight loss, loss of appetite, night sweats, fatigue, and bone pain.
Arsenox 1mg Injection Indication
The Arsenox 1mg Injection is prescribed in the following indications as acute promyelocytic leukemia
Mechanism of action of Arsenox 1mg Injection
Arsenox 1mg Injection contains Arsenic Trioxide 1mg is an anti-cancer medication, an apoptosis inducer. Though the process is unknown, the result is morphological changes of DNA strands causing breaks in DNA strands and apoptosis of DNA. Thus, treats leukemia.
How Arsenox 1mg Injection works
Arsenox 1mg Injection contains Arsenic Trioxide 1mg is an anti-cancer medication, an apoptosis inducer. It produces its action by changing the structure of DNA of abnormal cancer cells thus treating leukemia.
Arsenox 1mg Injection Contraindication
Do not take this medicine if you are allergic to Arsenic trioxide
Arsenox 1mg Injection Side Effects
FAQs for Arsenox 1mg Injection
Yes, the use of this medicine is considered safe if you have taken the medicine as per the dose and duration advised by the doctor.
Yes, the common side effect of this medicine is nausea and fatigue so it is better to eat more frequent meals to decrease nausea and also avoid foods that are salty, spicy, fatty. Drink plenty of rest and do light exercise to keep yourself active
Use sunscreen whenever you step outdoors and use moisturizer to get relief from the rash, dry and itchy skin. Your skin will return to normal once your treatment is stopped.
Precautions and general warning of Arsenox 1mg Injection
Alcohol
It is not clear whether it is safe to consume alcohol is safe while you are receiving this medicine. Kindly consult with your doctor.
Driving or operating machinery
It is considered safe to drive while you are receiving this medicine it does not affect your ability to drive. Kindly consult with your doctor.
Pregnancy
The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor
Breast Feeding
The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor
Kidney Problem
Limited information is available regarding the use of this medicine in patients who are with renal impairment. Kindly consult with your doctor.
Liver Disease
Limited information is available regarding the use of this medicine in patients who are with hepatic impairment. Kindly consult with your doctor.
How to Take Arsenox 1mg Injection
Arsenox 1mg Injection comes in a liquid solution as an intravenous. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.
Use of Arsenox 1mg Injection in Adult
It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.
Use of Arsenox 1mg Injection in children
Safety and efficacy were not established. Kindly consult with your doctor.
Use of Arsenox 1mg Injection in Elderly Patients
Arsenox 1mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.
Other general warnings
Talk to your doctor if
General instructions
Arsenic Trioxide 1mg is used to treat acute promyelocytic leukemia. It produces its action by changing the structure of DNA of abnormal cancer cells thus treating leukemia.
Drug Interaction of Arsenox 1mg Injection
Drug-Drug Interaction
Artemether
It is contraindicated to use this medicine because the combination of this medicine increases the QTc interval
Saquinavir
Use alternative drug because the combination of this medicine either increases the toxicity of the other by pharmacodynamic synergism
Cholera vaccine
Therapy should be administered with caution because the use of arsenic trioxide decreases the effect of cholera vaccine by immunosuppressive effect and it also increases the risk for infection
Drug-Food Interaction
No data is available. Kindly consult with your doctor
Drug-Disease Interaction
Conduction abnormalities
The use of this medicine may cause QTc interval prolongation so before initiating the treatment with arsenic trioxide kindly check the QTc interval by electrocardiogram
Encephalopathy
Wernicke's encephalopathy occurred in patients was treated with arsenic trioxide injection. If you have suspected encephalopathy immediately discontinue arsenic trioxide injection and initiate parenteral thiamine.
Over Dose
Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.
Missed Dose
Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).
Storage and Disposal
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