Astafix SB Tablet

Astafix SB Tablet contains Cefixime 200mg and Salbactum 150mg used to treat conditions like Bacterial infections, Urinary Tract Infection, Pneumonia, Ear infection, Tonsillitis/Pharyngitis, Gonorrhoea, and Skin and structure infection. Cefixime 200mg is an antibiotic used to treat infections and it mainly targets the ear, eyes, nose, throat, lungs, skin, gastrointestinal tract, and urinary tract bacterial infection.  Sulbactam 150mg is a β lactamase inhibitor. It should be given with antibiotic, which works by inhibiting the β lactamase enzyme(destroys the action of antibiotics) produced by bacteria.  The combination of this medicine helps to fight against microbes and also prevents the growth of bacteria. This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial infections. Swallow the whole tablet at once. Don’t break, chew, or crush the tablet

It is used in the treatment of the following conditions as Bacterial infections, Urinary Tract Infection, Pneumonia, Ear infection, Tonsillitis/Pharyngitis, and Skin and structure infection.

Bacterial infections

Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

Urinary tract infection

It is a type of infection that affects the urethra, kidneys, and bladder. It is caused by Escherichia coli (E.coli). Symptoms include abdominal pain, frequent urination, dysuria, blood in urine, foul-smell while urinating

Acute bronchitis

It is a viral infection that causes inflammation in the bronchial tubes. It is mostly caused by rhinovirus, adenovirus, influenza A and B, and parainfluenza virus. Symptoms include cough, fatigue, breathing difficulty, fever and chills, and chest discomfort.

Lower respiratory tract infections

Infection in the lungs especially in the lower airways Common infections are Bronchiolitis and Pneumonia which are caused by Streptococcus pneumonia. Symptoms include runny nose, dry cough, sore throat, low-grade fever, and headache.

Skin infection

It is usually caused by bacteria, fungi, viruses, and parasites. Common skin infection includes cellulitis, impetigo. Symptoms include red skin, blisters, swelling, pain, red spots, and tenderness

Tonsillitis/Pharyngitis

Infection of the swelling and soreness in the throat and tonsils is called pharyngitis and tonsillitis. The infection that affects both throat and tonsil is called pharyngotonsillitis. It is caused by bacteria.

Otitis media

It is also called as ear infections. While comparing with adults children are more prone to this infection. It is caused by Streptococcus pneumonia. Symptoms include ear pain, difficulty in sleeping, loss of balance, headache, loss of appetite and drainage of fluid from the ear.

Pneumonia

It is a lung infection that causes inflammation in the alveoli. It is usually caused by Streptococcus pneumonia. Symptoms include chest pain, fatigue, fever, sweating, nausea, vomiting, diarrhea, breathing difficulty, cough, and confusion

Astafix SB Tablet is prescribed in the following indications as Bacterial infections, Urinary Tract Infection, Pneumonia, Ear infection, Tonsillitis/Pharyngitis, and Skin and structure infection.

Astafix SB Tablet contains Cefixime 200mg and Sulbactam 150mg it is a combination of two medicines. Cefixime 200mg is a third-generation cephalosporin antibiotic that produces its action by preventing bacterial cell wall synthesis which is essential for the growth of bacteria and it also prevents the spreading of infections. Sulbactam 150mg is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of Cefixime. The combination with Subactum helps to reduce the development of resistance and increase the action of Cefixime against bacteria.

Astafix SB Tablet contains Cefixime 200mg and Sulbactam 150mg it is a combination of two medicines. Cefixime 200mg is a third-generation cephalosporin antibiotic that produces its action by preventing bacterial cell wall synthesis which is essential for the growth of bacteria and it also prevents the spreading of infections. Sulbactam 150mg is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of Cefixime. The combination with Subactum helps to reduce the development of resistance and increase the action of Cefixime against bacteria.

• Do not take this medicine if you are allergic to penicillins, cephalosporins, and Carbapenems
• The use of this medicine increases the risk of developing bacterial or fungal superinfections
• It is contraindicated to use this medicine if you are having a previous history of cholestatic jaundice, hepatic dysfunction
• The use of this medicine may cause toxic epidermal necrolysis, Stevens-Johson syndrome, dermatitis exfoliative.

• Diarrhea
• Nausea
• Stomach pain
• Indigestion
• Flatulence
• Swelling
• Rash
• Itching
• Breathing difficulty

• How long does the Astafix SB Tablet take to work?

Usually, it starts to work as soon as you consume the medicine. But, it may take some days to kill the microbes which are responsible for infection and make you feel better.

• What if I don’t get better after using the Astafix SB Tablet?

If you don’t feel better after you finish the full course of treatment. Kindly inform your doctor before your symptoms get worsen.

• Can I stop taking the Astafix SB Tablet when I feel better?

No, without completing the full course of treatment you should not withdraw your treatment even if you feel better. Because your symptoms may get worsen

Alcohol

It is not clear that consuming alcohol may produce harmful effects while you are receiving this medicine. Kindly consult with your doctor.

Driving or operating machinery

It is not clear that while you are receiving this medicine it may affect your ability to drive or not. Kindly consult with your doctor.

Pregnancy

The use of this medicine is considered safe during pregnancy because it does not produce any harmful effects. Kindly consult with your doctor

Breast Feeding

The use of this medicine is considered safe during breastfeeding because it does not excrete via breast milk. Kindly consult with your doctor

Kidney Problem

The medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

Liver Disease

The medicine should be used with caution in patients with severe liver impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

Astafix SB Tablet is taken orally with or without food. You should not chew, cut or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.

It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.

Astafix SB Tablet is not prescribed in children who are below 6 months old. Kindly consult with your doctor.

Astafix SB Tablet should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.

• Therapy should be administered with caution if you have a history of penicillin allergy and gastrointestinal disease
• Long-term use may cause bacterial or fungal overgrowth
• The use of this medicine may cause Immune-mediated hemolytic anemia, kindly discontinue the treatment if you have anemia
• The use of this medicine may cause a renal failure like tubulointerstitial nephritis
• It produces limited effect against anaerobes
• Higher risk for developing superinfection

• You have a history of gastrointestinal disease
• You are not responding to the treatment
• You have experienced any allergic reaction like rashes and itching
• You are suffering from anemia
• You have watery diarrhea, stomach pain, and fever

Astafix SB Tablet contains Cefixime 200mg and Salbactum 150mg used to treat conditions like Bacterial infections, Urinary Tract Infection, Pneumonia, Ear infection, Tonsillitis/Pharyngitis, Gonorrhoea, and Skin and structure infection.

Cefixime 200mg is an antibiotic used to treat infections and it mainly targets the ear, eyes, nose, throat, lungs, skin, gastrointestinal tract, and urinary tract bacterial infection.  Sulbactam 150mg is a β lactamase inhibitor. It should be given with antibiotic, which works by inhibiting the β lactamase enzyme(destroys the action of antibiotics) produced by bacteria.  The combination of this medicine helps to fight against microbes and also prevents the growth of bacteria

Drug-Drug Interaction

BCG vaccine live

The use of this drug is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism

Cholera vaccine

Use alternative drugs, because the use of the cholera vaccine with antibiotics may activate the vaccine strain. So, avoid receiving this combination of medicines before 14 days of vaccination

Estradiol

Therapy should be administered with caution because the use of cefixime will decrease the effect of estradiol by altering the intestinal flora and it also lowers the risk of contraceptive failure

Warfarin

Therapy should be administered with caution because the combination of this drug may decrease the vitamin K producing intestinal flora and increase the INR level after a few days

Furosemide

The use of cefixime increase the toxicity of furosemide by pharmacodynamic synergism and it also increases the risk of developing nephrotoxicity

Aspirin

The use of cefixime will increase the effect of aspirin by acidic drug competition for renal tubular clearance.

Drug-Food Interaction

The food may increase the effect of the drug in your body so it is advised to take this tablet with food to increase the absorption

Drug-Disease Interaction

Colitis

This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This drug should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient’s health condition.

Kidney disease

This medicine is filtered by the kidneys and passes through the urine. Then it leads to the risk of kidney damage. It should be used with caution in a patient with kidney disease. Inform your doctor and then take. Based on the patient's condition, dose adjustment is needed.

Seizures

Using this medicine is needs caution in patients with seizures or fits. Inform the doctor, then will do dose adjustment if necessary to take this medicine with seizure medications.

Diarrhea

This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. It leads to worsening the patient’s health condition. Better to take probiotics with this medicine to avoid diarrhea.

Lab interactions

This medicine gives a false positive test for Coombs test and Urine ketones test.

Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.

Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).

• Stored at 10-30°C room temperature.
• Protect from light and heat.
• Keep away from children and pets. Otherwise, it becomes toxic to them.
• Disposed of properly in a suitable bag.

Astafix SB Tablet contains Cefixime 200mg and Salbactum 150mg used to treat conditions like Bacterial infections, Urinary Tract Infection, Pneumonia, Ear infection, Tonsillitis/Pharyngitis, Gonorrhoea, and Skin and structure infection.

Cefixime 200mg is a third-generation cephalosporin antibiotic used to treat bacterial infections. Mainly bacterial infection targets the ear, eyes, nose, throat, lungs, skin, stomach, and urinary tract.

Sulbactam 150mg is a β lactamase inhibitor. It should be given with antibiotic, to inhibit the β lactamase enzyme produced by bacteria. This enzyme destroys the action of antibiotics. This drug combination together prevents the infection effectively.

This medicine is not used for common flu and cold symptoms. And not treat viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial infections.