Atazor 300 Capsule

Atazor 300 Capsule contains Atazanavir 300mg. Atazor 300 (Atazanavir (300mg)) Capsule is an antiviral medicine used in the treatment of Human Immunodeficiency Virus (HIV) infection. Atazor 300 Capsule acts as a protease inhibitor. Atazanavir works by reducing the viral load of HIV in your body. Atazor 300 Capsule improves your immune system and reduces the risk of conditions associated with HIV infection. Atazor 300 Capsule is used in children above 6 years old and in adults. Atazor 300 Capsule is used in combination with other antiviral medications like ritonavir.

Atazor 300 (Atazanavir (300mg)) Capsule is used to treat adults and children above 6 years of age who are infected by HIV. Atazor 300 Capsule must be taken in combination with a low dose of other anti-HIV medicines like ritonavir. Your doctor will discuss which combination of medicines is best for you.

Atazor 300 (Atazanavir (300mg)) Capsule is used with other anti-HIV medicines to help control HIV infection. Atazor 300 Capsule helps to decrease the amount of HIV virus in your body thus your immunity works better by reducing your chance of getting HIV complications like co-infections and other cancers. Atazor 300 Capsule is a protease inhibitor. Atazor 300 Capsule is not a cure for HIV infection, it improves immunity that results in longevity of life. Atazanavir is not recommended for use in children less than 6 years due to the increased risk of serious side effects.

Atazor 300 (Atazanavir (300mg)) Capsule is indicated in the treatment of HIV infection that causes AIDS in humans. Atazor 300 Capsule is used with other antiviral medications to boost the immunity of the affected hosts by reducing the viral load of the infected cells. Atazor 300 Capsule is indicated in ages above 6 years.

Atazor 300 (Atazanavir (300mg)) Capsule is an HIV protease inhibitor. Protease inhibitors are used as a part of highly active antiviral therapy (HAART) in HIV-infected patients. Atazor 300 Capsule prevents HIV replication by binding to this specific enzyme thus selectively inhibits the cleavage of HIV-1 encoded Gag-Pol polyproteins in cells affected by the virus, thereby preventing the formation of mature virus particles into infectious virions that spreads the infection. Atazor 300 Capsule is a structural analogue of the transition state that binds to different sites on the enzyme namely the active site and the surface of one of the flexible flaps in the protease dimer during which the bond between phenylalanine and proline is broken.

Atazor 300 (Atazanavir (300mg)) Capsule is an HIV protease inhibitor. Atazor 300 Capsule binds to different sites on the enzyme namely the active site and the surface of one of the flexible flaps in the protease dimer. Atazanavir prevents HIV replication by binding to this specific enzyme thus selectively inhibits the cleavage of HIV-1 encoded Gag-Pol polyproteins in cells affected by the virus, thereby preventing the formation of mature virus particles into infectious virions that spreads the infection.

Absolute contraindications:

• if you are allergic to Atazor 300 (Atazanavir (300mg)) Capsule
• if you have severe liver problems like hepatitis or hepatic insufficiency
• if you are breastfeeding
• if <6 yrs of age

Relative contraindication:

• if you have kidney disease
• if you are diabetic
• if you have a bleeding disorder like haemophilia
• if you have a lipid disorder like hyperlipidaemia
• if you have heart diseases
• if you are pregnant – this medication lowers the risk of passing HIV infection to the baby

Common side effects that occur 1:10 patients: headache, ocular icterus, vomiting, diarrhea, abdominal pain, nausea, dyspepsia, jaundice, rash, fatigue

Uncommon side effects that occur 1:100 patients: hypersensitivity, weight decreased, weight gain, anorexia, appetite increased, depression, disorientation, anxiety, insomnia, sleep disorder, abnormal dream, peripheral neuropathy, syncope, amnesia, dizziness, hypertension, dyspnoea, pancreatitis, gastritis, abdominal distension, stomatitis aphthous, flatulence, dry mouth, hepatitis, cholelithiasis, cholestasis, erythema multiforme, toxic skin eruptions, medicine rash with eosinophilia and DRESS syndrome, angioedema, urticaria

Rare side effects that occur in 1:1000 patients: gait disturbance, kidney pain, myopathy, Stevens-Johnson syndrome, vesiculobullous rash, eczema, vasodilatation, hepatosplenomegaly, cholecystitis, QTc prolongation, edema, palpitation.

Is Atazor 300 (Atazanavir (300mg)) Capsule safe during pregnancy?

This medication is not recommended in pregnancy unless the pros outweigh the cons. Consult your physician.

Can Atazor 300 Capsule be taken while breastfeeding?

There is no specific study to detail this. But in general HIV virions can pass via breastfeeding thus it is suspected that antivirals can also pass via breastfeeding. Thus, consult your physician.

Can Atazor 300 Capsule be taken while alcohol consumption?

The interaction is unknown. Thus, consult your physician.

Can I take painkillers with Atazor 300 Capsule?

The safest pain killer to be taken with Atazor 300 Capsule is paracetamol but prolonged usage should be taken only when advised by the physician.

Can I take health supplements with Atazor 300 Capsule?

Yes, most health supplements that contain calcium or iron can be taken. For precautious use kindly consult your physician.

Alcohol

Atazor 300 (Atazanavir (300mg)) Capsule generally causes blurry vision, fainting, and movement disorders thus it is advised not to be taken with alcohol. For further queries, consult your physician.

Driving or operating machinery

It is preferred to drive or operate heavy machinery with caution as Atazor 300 (Atazanavir (300mg)) Capsule causes fainting spells and movement disorders. For further queries, consult your physician.

Pregnancy

The use of Atazor 300 (Atazanavir (300mg)) Capsule is cautiously used during pregnancy. In addition, it decreases the rate of HIV transmission to the fetus and decreases the mortality rate. Thus, consult your physician.

Breast Feeding

The use of Atazor 300 (Atazanavir (300mg)) Capsule during breastfeeding is not recommended as evidence shows less amount of the medication passes via breastfeeding to the baby that may cause adverse effects in newborn.

Kidney Problem

Renal calculus and renal filtration impairment – monitor function. For further queries, consult your physician.

Liver Disease

Inform your physician if you have hepatitis B or C or any history of gall stones because Atazor 300 (Atazanavir (300mg)) Capsule could cause abnormal liver function. Thus, monitor with regular blood work.

Atazor 300 (Atazanavir (300mg)) Capsule is taken orally with food.

Don’t open the capsule.

Swallow Atazor 300 Capsule as a whole.

Atazor 300 Capsule must be taken with ritonavir.

After therapy has been initiated, do not take more or less of Atazor 300 than prescribed or stop taking it without your physicians’ approval. Skipping or changing Atazor 300 Capsule dose without approval would increase the viral load making the infection more difficult to treat, or worsen side effects. For further queries consult your physician.

If you are pregnant or breastfeeding inform your physician as they are not advisable.

The recommended dose of Atazor 300 Capsule is 300mg taken with ritonavir 100mg once daily and with food.

Atazor 300 (Atazanavir (300mg)) Capsule must be taken with ritonavir as prescribed by the physician without fail. These drugs must be taken with food and the medicine must be swallowed.

Atazor 300 (Atazanavir (300mg)) Capsule is used in children above age 6 who are not below 15kgs weight

Atazor 300 Capsule must be taken with ritonavir as prescribed by the physician without fail. These drugs must be taken with food and the medicine must be swallowed

Atazor 300 (Atazanavir (300mg)) Capsule has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.

• Any sign of infection – fever or lymph node enlargement
• Musculoskeletal problems - Osteonecrosis that causes joint stiffness and pain in larger joints like shoulder, hip, and knee
• Hyperbilirubinemia – yellowing of eyes, mouth, and skin accompanied by brown or yellow urine and colorless stool.
• Skin reactions - It can be mild to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.
• Heart diseases or disorders – especially in children.
• Avoid in case of patients below 3 months of age
• Accumulation or Redistribution of body fat or immune reconstitution syndrome.
• Haemophilia may develop increased bleeding events.

If you have any allergy

If you have a liver problem

If you have any kidney diseases

If you have hypertension or any heart problem

If you have any bleeding problem

If you are pregnant or breastfeeding

Atazor 300 (Atazanavir (300mg)) Capsule is taken with ritonavir orally as prescribed dosage at a specific time regularly with food. If Atazor 300 Capsule is taken separately or without food, the efficiency of the medicine is reduced significantly, thus it is ill-advised.

Drug-Drug Interaction

Decreased metabolism caused by Alfuzosin, Sildenafil

Increased metabolism caused by Rifampin

Increased Serum concentration caused by midazolam, Lovastatin, simvastatin

Increased severity of side effects by Aceclofenac, Amphotericin B

Drug-Food Interaction

Atazor 300 (Atazanavir (300mg)) Capsule can be safely taken with any type of food, if doubts arise kindly refer to your physician. Atazor 300 Capsule generally causes blurry vision, fainting, and movement disorders thus it is advised not to be taken with alcohol.

Drug-Disease Interaction

• Liver disorders – used with caution in severe liver diseases. Consult a physician before use
• Kidney disorders – used with caution in severe kidney diseases. Consult a physician before use
• Cardiac disorders – used with caution in heart failure and MI. Consult a physician before use
• Respiratory disorders – used with caution in respiratory distress. Consult a physician before use
• Blood disorders – used with caution in anemia and thrombocytopenia. Consult a physician before use

Symptoms of overdose include dizziness, palpitations, etc. Contact your doctor immediately.

You can take the missed dosage if you notice within 6 hours. Always take with ritonavir and food. If it is more than 6 hours, then skip the dosage and take the next doses as usual. Don’t take a double dose for a forgotten dose.

Store them away from heat and moisture

Keep the medication out of children’s reach

Keep the medication away from pets

Once expired dispose immediately

Atazor 300 Capsule contains Atazanavir 300mg.

Atazor 300 (Atazanavir (300mg)) Capsule is a protease inhibitor.

Atazor 300 Capsule used to control and treat HIV infection with Ritonavir

Do not use this medication while pregnant and lactation period.

Don’t use this medication with liver disease, kidney disease, and bleeding disorder.

This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury, etc.