Augtax 250mg/125mg Injection

Brand Name Augtax 250mg/125mg Injection
Salt Composition

Cefotaxime (250mg) + Sulbactam (125mg)

Strength 250mg + 125mg
Product Form Injection
Pack 1 x 10ml in 1 Vial
Storage Store below 30°C
Category

Antibiotic

SubCategory

Anti-Biotic

Country of Origin India
Manufacturer

Zuventus Healthcare Ltd

Manufacturer/Marketer Address Zuventus Healthcare Ltd, Office No. 5119, 5th Floor, 'D' Wing, Oberoi Garden Estates, Chandivili, Andheri (E), Mumbai - 400 072.
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M.R.P : Rs.59.12       Price : Rs.53.21

You Save : Rs.5.91    Inclusive of all taxes

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1 x 10ml in 1 Vial

Availability : In Stock

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    Medical Description of Augtax 250mg/125mg Injection

    The Augtax 250mg/125mg Injection contains Cefotaxime 250mg and Sulbactam 125mg used to treat bacterial infections such as Urinary tract infections, Pneumonia, Bacterial meningitis, Bacterial septicemia, Skin, and soft tissue infections, Pelvic inflammatory disease, Osteomyelitis (Bone and joint infection), and Gonorrhoea.  Cefotaxime 250mg is an antibiotic used to treat infections and is also used to prevent the infection that occurs after surgery. Mainly this bacterial infection targets the lungs, nose, skin and soft tissues, bone and joints, female reproductive organs, blood, heart, and urinary tract. Sulbactam 125mg is a β lactamase inhibitor. It should be given with antibiotic, which works by inhibiting the β lactamase enzyme (destroys the action of antibiotics) produced by bacteria.  The combination of this medicine helps to fight against microbes and also prevents the growth of bacteria. This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial infections.


    Augtax 250mg/125mg Injection Uses

    It is used in the treatment of the following conditions as Urinary tract infections, Pneumonia, Bacterial meningitis, Bacterial septicemia, Skin, and soft tissue infections, Pelvic inflammatory disease, Osteomyelitis (Bone and joint infection), and Gonorrhoea


    Augtax 250mg/125mg Injection Benefits

    Bacterial infections

    Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

    Urinary tract infection

    It is a type of infection that affects the urethra, kidneys, and bladder. It is caused by Escherichia coli (E.coli). Symptoms include abdominal pain, frequent urination, dysuria, blood in urine, foul-smell while urinating

    Gonorrhea

    It is a sexually transmitted infection caused by bacteria called Neisseria gonorrhoeae. It affects both males and females. Symptoms include thick discharge from the penis, increased vaginal discharge, pain while urinating, anal itching, discharge, and spotting between menstrual bleeding.

    Acute bronchitis

    It is a viral infection that causes inflammation in the bronchial tubes. It is mostly caused by rhinovirus, adenovirus, influenza A and B, and parainfluenza virus. Symptoms include cough, fatigue, breathing difficulty, fever and chills, and chest discomfort.

    Bone and joint infection

    Bone infection is also called Osteomyelitis. It is caused by bacteria called staphylococcus which travels through the bloodstream to the weak area in a bone. Symptoms include fever, pain, fatigue, tenderness, redness, and warmth.

    Lower respiratory tract infections

    Infection in the lungs especially in the lower airways Common infections are Bronchiolitis and Pneumonia which are caused by Streptococcus pneumonia. Symptoms include runny nose, dry cough, sore throat, low-grade fever, and headache.

    Pneumonia

    Infection and inflammation to the respiratory air sacs of lungs called pneumonia caused by bacteria. This medicine is used to treat this bacterial infection.

    Bacterial meningitis

    Infection and inflammation to the meninges (in the brain) caused by bacteria called bacterial meningitis. This medicine is used to treat this bacterial infection.

    Bacterial septicemia

    Infection of the blood caused by bacteria leads to increased toxins in the bloodstream passes to the entire body develops organ damage. This medicine is used to treat this bacterial infection.

    Pelvic inflammatory disease

    Infection to the female reproductive organs caused by bacteria is called Pelvic inflammatory disease. This medicine is used to treat this bacterial infection.


    Augtax 250mg/125mg Injection Indication

    The Augtax 250mg/125mg Injection is prescribed in the following indications as Urinary tract infections, Pneumonia, Bacterial meningitis, Bacterial septicemia, Skin, and soft tissue infections, Pelvic inflammatory disease, Osteomyelitis (Bone and joint infection), and Gonorrhoea


    Mechanism of action of Augtax 250mg/125mg Injection

    The Augtax 250mg/125mg Injection contains Cefotaxime 250mg and Sulbactam 125mg is the combination of two medicines. Cefotaxime 250mg is a third-generation cephalosporin antibiotic that produces its action by preventing bacterial cell wall synthesis which is essential for the growth of bacteria and also prevents the spreading of infections. Sulbactam 125mg is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of the antibiotic. The combination with Subactum helps to reduce the development of resistance and increase the action of Cefotaxime against bacteria.


    How Augtax 250mg/125mg Injection works

    The Augtax 250mg/125mg Injection contains Cefotaxime 250mg and Sulbactam 125mg is the combination of two medicines. Cefotaxime 250mg is a third-generation cephalosporin antibiotic that produces its action by preventing bacterial cell wall synthesis which is essential for the growth of bacteria and also prevents the spreading of infections. Sulbactam 125mg is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of the antibiotic. The combination with Subactum helps to reduce the development of resistance and increase the action of Cefotaxime against bacteria.


    Augtax 250mg/125mg Injection Contraindication

    • Do not take this medicine if you are allergic to Cefotaxime and Sulbactam
    • Kindly avoid this medicine if you are having hepatic and renal impairment, Seizures
    • The use of this medicine may cause Immune-mediated hemolytic anemia


    Augtax 250mg/125mg Injection Side Effects

    • Colitis
    • Diarrhea
    • Elevated blood urea nitrogen
    • Eosinophilia
    • Fever
    • Injection site pain
    • Nausea
    • Pruritus
    • Rash
    • Thrombocytopenia
    • Transient neutropenia


    FAQs for Augtax 250mg/125mg Injection

    • Is the Augtax 250mg/125mg Injection the same as penicillin?

    No, this is the same as penicillin and this medicine comes under 3RD generation cephalosporins and it is effective against gram-positive and gram-negative bacteria.

    • Is the Augtax 250mg/125mg Injection is effective?

    Yes, it is considered effective when you have taken the medication as per the dose and duration advised by the doctor. If you stop the medicine without completing the course of treatment it may worsen the conditions

    • What if I do not get better after using the Augtax 250mg/125mg Injection?

    If you do not feel better after completing the full course of treatment kindly inform your doctor.


    Precautions and general warning of Augtax 250mg/125mg Injection

    Alcohol

    The use of alcohol may produce harmful effects while you are receiving this treatment. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered safe during pregnancy because it does not produce a harmful effect on the developing fetus. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered safe during breastfeeding because it does not excrete via breast milk. Kindly consult with your doctor

    Kidney Problem

    The medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor

    Liver Disease

    It is considered safe to use this medicine in patients who are having a hepatic impairment. The use of this medicine does not require dose modification. Kindly consult with your doctor.


    How to Take Augtax 250mg/125mg Injection

    Augtax 250mg/125mg Injection comes in a liquid solution as an intravenous injection. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Augtax 250mg/125mg Injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.


    Use of Augtax 250mg/125mg Injection in children

    The Augtax 250mg/125mg Injection is not prescribed in children who are below 12 years old. Kindly consult with your doctor.


    Use of Augtax 250mg/125mg Injection in Elderly Patients

    The Augtax 250mg/125mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • Arrhythmia was reported in patients who are receiving bolus injection through the central venous catheter
    • At long-term treatment the use of this medicine associated with granulocytopenia
    • Therapy should be administered with caution in patients who are having a history of penicillin allergy and colitis
    • Long-term use may cause bacterial or fungal overgrowth
    • Adjust the dose in renal impairment patients


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You are having any concomitant disease or disorder


    General instructions

    Cefotaxime 250mg is a third-generation cephalosporin antibiotic that produces its action by preventing bacterial cell wall synthesis which is essential for the growth of bacteria and also prevents the spreading of infections. Sulbactam 125mg is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of the antibiotic.


    Drug Interaction of Augtax 250mg/125mg Injection

    Drug-Drug Interaction

    BCG vaccine live                            

    The use of this drug is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism

    Cholera vaccine

    Use alternative drugs, because the use of the cholera vaccine with antibiotics may activate the vaccine strain. So, avoid receiving this combination of medicines before 14 days of vaccination

    Estradiol

    Therapy should be administered with caution because the use of cefotaxime will decrease the effect of estradiol by altering the intestinal flora and it also lowers the risk of contraceptive failure

    Warfarin

    Therapy should be administered with caution because the combination of this drug may decrease the vitamin K producing intestinal flora and increase the INR level after a few days

    Furosemide

    The use of cefotaxime increase the toxicity of furosemide by pharmacodynamic synergism and it also increases the risk of developing nephrotoxicity

    Aspirin

    The use of cefotaxime will increase the effect of aspirin by acidic drug competition for renal tubular clearance.

    Drug-Food Interaction

    The food may increase the effect of the drug in your body so it is advised to take this tablet with food to increase the absorption

    Drug-Disease Interaction

    Colitis

    This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This drug should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient’s health condition.

    Kidney disease

    This medicine is filtered by the kidneys and passes through the urine. Then it leads to the risk of kidney damage. It should be used with caution in a patient with kidney disease. Inform your doctor and then take. Based on the patient's condition, dose adjustment is needed.

    Seizures

    Using this medicine is needs caution in patients with seizures or fits. Inform the doctor, then will do dose adjustment if necessary to take this medicine with seizure medications.

    Lab interactions

    This medicine gives a false positive test for Coombs test and Urine ketones test.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • The Augtax 250mg/125mg Injection contains Cefotaxime 250mg and Sulbactam 125mg used to treat bacterial infections such as Urinary tract infections, Pneumonia, Bacterial meningitis, Bacterial septicemia, Skin, and soft tissue infections, Pelvic inflammatory disease, Osteomyelitis (Bone and joint infection), and Gonorrhoea.
    • Cefotaxime 250mg is a third-generation cephalosporin antibiotic used to treat bacterial infections. It blocks the bacterial cell wall synthesis which is essential for bacterial growth. Sulbactam 125mg is a β lactamase inhibitor. It should be given with antibiotic, to inhibit the β lactamase enzyme (destroys the action of antibiotics) produced by bacteria. Also, used as surgical prophylaxis during surgery.
    • This medicine is not used for common flu and cold symptoms. And not treat viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial infections.