Axzyb 5mg Tablet

Brand Name Axzyb 5mg Tablet
Salt Composition

Axitinib (5mg)

Strength 5mg
Product Form Tablet
Pack 30 Tablet(s) in Bottle
Storage Store below 30°C
Category

Anti-Cancer

SubCategory

Kidney Cancer

Country of Origin India
Manufacturer

Glenmark Pharmaceuticals Ltd

Manufacturer/Marketer Address Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
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Axzyb 5mg Tablet, Axitinib 5mg Tablet, Price, Uses, Side Effects – Drugcarts watermark
M.R.P : Rs.4200.00       Price : Rs.3360.00

You Save : Rs.840.00    Inclusive of all taxes

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30 Tablet(s) in Bottle

Availability : In Stock

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    Medical Description of Axzyb 5mg Tablet

    Axzyb 5mg Tablet contains Axitinib 5mg used to treat renal cell carcinoma in adult patients. It is used in patients who have not responded to the previous treatment for kidney cancer. Axitinib helps to inhibit the growth and multiplication of cancer cells and reduce the progression of the diseases.


    Axzyb 5mg Tablet Uses

    It is used in the treatment of the following conditions as kidney cancer known as renal cell carcinoma. 


    Axzyb 5mg Tablet Benefits

    Renal cell carcinoma

    It is also called hypernephroma, renal adenocarcinoma, and kidney cancer. It is commonly found in adults. Factors that increase the risk of kidney cancer include older age, smoking, obesity, hypertension, family history. Symptoms include blood in urine, loss of appetite, weight loss, tiredness, and fever


    Axzyb 5mg Tablet Indication

    The Axzyb 5mg Tablet is prescribed in the following indications as kidney cancer known as renal cell carcinoma. 


    Mechanism of action of Axzyb 5mg Tablet

    Axzyb 5mg Tablet contains Axitinib 5mg is an anti-cancer medication called tyrosine kinase inhibitor. It produces its action by inhibiting the effect of abnormal protein, which promotes the growth and spread of cancer cells and it also helps to inhibit the growth of cancer cells.


    How Axzyb 5mg Tablet works

    Axzyb 5mg Tablet contains Axitinib 5mg is an anti-cancer medication called tyrosine kinase inhibitor. It produces its action by inhibiting the effect of abnormal protein, which promotes the growth and spread of cancer cells and it also helps to inhibit the growth of cancer cells.


    Axzyb 5mg Tablet Contraindication

    Do not take this medicine if you are allergic to Axitinib


    Axzyb 5mg Tablet Side Effects

    • Diarrhea
    • Hypertension
    • Decreased appetite
    • Weight loss
    • Asthenia
    • Constipation
    • Hypothyroidism
    • Mucosal inflammation
    • Stomatitis
    • Abdominal pain
    • Dry skin
    • Dizziness


    FAQs for Axzyb 5mg Tablet

    • Does Axzyb 5mg Tablet affect fertility?

    Yes, the use of this medicine may affect fertility in males as well as in females. Kindly consult with your doctor before initiating the treatment to preserve fertility.

    • What are the possible signs and symptoms of kidney cancer?

    Signs and Symptoms of kidney cancer include blood in urine, persistent pain, pressure below the ribs, intense fatigue.

    • What lab tests are important before starting the Axzyb 5mg Tablet?

    Your doctor will advise you to take blood pressure, thyroid function, kidney function, liver, and pancreatic function tests, complete blood count, urine test


    Precautions and general warning of Axzyb 5mg Tablet

    Alcohol

    It is not clear that consuming alcohol is safe while you are receiving this medicine. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor

    Kidney Problem

    It is considered safe to use this medicine in patients who are having a renal impairment. Kindly consult with your doctor.

    Liver Disease

    It is considered safe to use this medicine in patients who are having a hepatic impairment. Kindly consult with your doctor.


    How to Take Axzyb 5mg Tablet

    Axzyb 5mg Tablet is taken orally with or without food. You should not chew, cut or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Axzyb 5mg Tablet in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor


    Use of Axzyb 5mg Tablet in children

    Safety and efficacy were not established in children who are below 58 years old. Kindly consult with your doctor.


    Use of Axzyb 5mg Tablet in Elderly Patients

    Axzyb 5mg Tablet should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The use of this medicine may cause hypertension, hypertensive crisis, and arterial thromboembolic events like deaths
    • The patients who are having moderate hepatic impairment requires a dose reduction
    • The use of this medicine may cause elevated liver enzymes
    • The use of this medicine may cause proteinuria, thyroid dysfunctions, GI perforation, and formation of fistula
    • Hemorrhagic events like cerebral hemorrhage, hematuria, hemoptysis, GI bleeding, melena may occur
    • Venous thromboembolic events were reported


    Talk to your doctor if

    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have a receiving any concomitant medication and disease


    General instructions

    Axitinib 5mg is used to treat renal cell carcinoma in adult patients. Axitinib 5mg is an anti-cancer medication called tyrosine kinase inhibitor. It produces its action by inhibiting the effect of abnormal protein, which promotes the growth and spread of cancer cells and it also helps to inhibit the growth of cancer cells.


    Drug Interaction of Axzyb 5mg Tablet

    Drug-Drug Interaction

    Amiodarone

    Use alternative drugs because the use of amiodarone increases the effect of hepatic and intestinal enzyme metabolism.

    Dexlansoprazole

    The use of dexlansoprazole will decrease the effect of axitinib by increasing its gastric pH.

    Topiramate

    Therapy should be administered with caution because the use of topiramate decreases the effect of axitinib by affecting its hepatic and intestinal enzyme metabolism.

    Siponimod

    Therapy should be administered with caution because the combination of this medicine may increase the immunosuppressive effects and it also increases the risk of developing infections

    Drug-Food Interaction

    Axitinib 5mg should be taken on an empty stomach one hour before the meal or 2 hours after the meal. You should also avoid grapefruit juice while you are receiving this medicine it may increase the Axitinib 5mg in blood levels.

    Drug-Disease Interaction

    Hemorrhagic events

    Therapy should be administered with caution because the use of this medicine may cause fatal hemorrhagic events including hematuria, cerebral hemorrhage, hemoptysis, lower gastrointestinal hemorrhage, and melena were reported.

    GI perforation

    Therapy should be administered with caution in patients who are having a history of diverticulitis because they are having an increased risk for developing gastrointestinal perforation.

    Hepatic impairment

    Systemic exposure to this medicine is higher in patients with moderate hepatic impairment. So kindly monitor the patient's liver enzymes and bilirubin level before initiating the treatment.

    Reversible leukoencephalopathy syndrome

    Therapy should be administered with caution in patients with seizures, headaches, visual disturbances, confusion, and altered mental function because reversible posterior leukoencephalopathy was reported.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 50-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • Axzyb 5mg Tablet contains Axitinib 5mg used to treat renal cell carcinoma in adult patients. It is used in patients who have not responded to the previous treatment for kidney cancer. Axitinib helps to inhibit the growth and multiplication of cancer cells and reduce the progression of the diseases. This medication is recommended only for adults.
    • Take this medicine 5 hour before or 2 hours after your meal
    • Kindly inform your doctor if you have experienced headache, stomach pain, and blood in your stool and urine while you are receiving this medicine.