Azel 80mg Capsule

Brand Name Azel 80mg Capsule
Salt Composition

Enzalutamide (80mg)

Strength 80mg
Product Form Capsule
Pack 1 x 14's
Storage Store below 30°C
Category

Anti-Cancer

SubCategory

Prostate Cancer

Country of Origin India
Manufacturer

Dr. Reddy's Laboratories Ltd.

Manufacturer/Marketer Address Dr. Reddy's Laboratories Ltd,7-1-27, Ameerpet, Hyderabad, Andhra Pradesh, 500 016 India
-32.5%
Azel 80mg Capsule, Enzalutamide 80mg Capsule, Price, Uses, Side Effects – Drugcarts watermark
M.R.P : Rs.8700.00       Price : Rs.5872.50

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1 x 14's

Availability : In Stock

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    Medical Description of Azel 80mg Capsule

    Azel 80mg Capsule contains Enzalutamide 80mg used to treat metastasized Prostate cancer by inhibiting the action of testosterone, a male sex hormone. It is used in patients whose diseases are progressed even after the Docetaxel therapy. It is not recommended in females, children, and adolescents.


    Azel 80mg Capsule Uses

    It is used in the treatment of the following conditions as Prostate cancer


    Azel 80mg Capsule Benefits

    Prostate cancer

    It is cancer that occurs in a man’s prostate. Usually, it grows slowly and is confined to the prostate gland. Symptoms include difficulty in urinating, blood in urine, semen, bone pain, weight loss, and erectile dysfunction. This medicine helps to inhibit the multiplication of cancer cells.


    Azel 80mg Capsule Indication

    The Azel 80mg Capsule is prescribed in the following indications as

    • Castration-resistant
    • Chemotherapy with docextal has failed
    • Metastasis to other organs


    Mechanism of action of Azel 80mg Capsule

    Azel 80mg Capsule contains Enzalutamide 80mg is an anti-cancer medication, an Antiandrogen. It produces its action by inhibiting androgen binding to its androgen receptor which inhibits nuclear translocation required for proliferation and induces cell death. Thus, Enzalutamide decreases the volume of the prostate.


    How Azel 80mg Capsule works

    Azel 80mg Capsule contains Enzalutamide 80mg is an anti-cancer medication, an Antiandrogen. It produces its action by inhibiting androgen binding capacity to the androgen receptors by blocking nuclear translocation and treats prostate cancer by inhibiting the proliferation of cells in the prostate.


    Azel 80mg Capsule Contraindication

    Do not take this medicine if you are allergic to Enzalutamide


    Azel 80mg Capsule Side Effects

    • Back pain
    • Diarrhea
    • Upper respiratory tract infection
    • Hypertension
    • Weight loss
    • Dizziness
    • Peripheral edema
    • Hot flush
    • Hematuria
    • Insomnia
    • Dry skin


    FAQs for Azel 80mg Capsule

    • What blood tests are required before administration of the Azel 80mg Capsule?

    Before initiating the treatment with Azel you may be asked to have blood tests, liver function tests.

    • How and in what dose should I take the Azel 80mg Capsule?

    Take the medicine as per the dose and duration advice by the doctor. Take the dose daily without missing the frequency of the drug.

    • Can I stop using the Azel 80mg Capsule immediately or do I have to slowly wean off the use?

    You should not withdraw the medicine immediately, you should taper the dose to avoid rebound effects.


    Precautions and general warning of Azel 80mg Capsule

    Alcohol

    It is considered unsafe to consume alcohol while you are receiving this medicine. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor

    Kidney Problem

    The medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    The medicine should be used with caution in patients with hepatic impairment. The use of this medicine required dose modification. Kindly consult with your doctor.


    How to Take Azel 80mg Capsule

    Azel 80mg Capsule is taken orally with or without food. You should not chew, cut or crush the capsule. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Azel 80mg Capsule in Adult

    It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.


    Use of Azel 80mg Capsule in children

    Safety and efficacy were not established in children. Kindly consult with your doctor.


    Use of Azel 80mg Capsule in Elderly Patients

    Azel 80mg Capsule should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The use of this medicine may cause seizure, posterior reversible encephalopathy syndrome, ischemic heart diseases, fall, and fractures.
    • Hypersensitivity includes facial edema were observed
    • Kindly avoid using this medicine in female patients because safety and efficacy were not reported.


    Talk to your doctor if

    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have a receiving any concomitant medication and disease
    • You develop shortness of breath


    General instructions

    Enzalutamide 80mg is used to treat metastasized Prostate cancer. It produces its action by inhibiting androgen binding capacity to the androgen receptors by blocking nuclear translocation and treats prostate cancer by inhibiting the proliferation of cells in the prostate.


    Drug Interaction of Azel 80mg Capsule

    Drug-Drug Interaction

    Atazanavir

    It is contraindicated to use this medicine because the use of atazanavir will increase the effect of enzalutamide by affecting its hepatic and intestinal enzyme metabolism.

    Siponimod

    Therapy should be administered with caution because the combination of this medicine increases the immunosuppressive effects and it also increases the risk of developing an infection

    Cannabidiol

    Therapy should be administered with caution because the use of cannabidiol will increase the effect of enzalutamide by decreasing its metabolism.

    Alfentanil

    Therapy should be administered with caution because the use of enzalutamide will decrease the effect of alfentanil by affecting its hepatic and intestinal enzyme metabolism.

    Drug-Food Interaction

    No data available kindly consult with your doctor

    Drug-Disease Interaction

    Renal impairment

    Therapy should be administered with caution in patients with end-stage renal diseases when compared with mild to moderate renal impairment patients because the studies have not been assessed in end-stage renal failure patients.

    Seizures

    Therapy should be administered with caution in patients with a history of seizures, trauma, head injury, ischemic attack, Alzheimer's diseases, and brain tumor because during the clinical trial the use of this medicine cause seizure in 0.5% of patients


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • Azel 80mg Capsule contains Enzalutamide 80mg used to treat metastasized Prostate cancer by inhibiting the action of testosterone, a male sex hormone. It is used in patients whose diseases are progressed even after the Docetaxel therapy. It is not recommended in females, children, and adolescents.     
    • Kindly avoid this medicine if you are a diabetic patients
    • Kindly avoid taking this medicine while you are pregnant
    • Avoid consuming alcohol while you are receiving this medicine because it may increase the risk of developing serious side effects.