Blastolem 50mg Injection

Brand Name Blastolem 50mg Injection
Salt Composition

Cisplatin (50mg)

Strength 50mg
Product Form Injection
Pack 50 ml in 1 vial
Storage Store below 30°C
Category

Anti-Cancer

SubCategory

Bladder Cancer

Country of Origin India
Manufacturer

Elder Pharmaceuticals Ltd

Manufacturer/Marketer Address Elder Pharmaceuticals Ltd,“Elder House” Plot No. C-9, Dalia Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai – 400053.
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M.R.P : Rs.511.96       Price : Rs.409.57

You Save : Rs.102.39    Inclusive of all taxes

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50 ml in 1 vial

Availability : In Stock


    Medical Description of Blastolem 50mg Injection

    Blastolem 50mg Injection contains Cisplatin 50mg used to treat ovarian cancer, bladder cancer, and testicular cancer. It works by inhibiting the growth of abnormal cells. It is used alone or with other combinations as chemotherapy.


    Blastolem 50mg Injection Uses

    It is used in the treatment of the following conditions ovarian cancer, bladder cancer, and testicular cancer.  


    Blastolem 50mg Injection Benefits

    Ovarian cancer

    It is a type of cancer that occurs in an ovary a female reproductive system that produces women’s eggs and female hormones. The exact is not clear but if you have a history of ovarian cancer in your family. Symptoms include abdominal bloating, weight loss, discomfort in the pelvic area, fatigue, back pain, constipation, and frequent urination. This medicine helps to inhibit the multiplication of cancer cells.

    Urothelial carcinoma

    It is also called bladder cancer. It is a type of cancer that begins in the cells in the bladder. It usually occurs when changes occur in the DNA. Symptoms include back pain, blood in urine, frequent urination, and pain while urinating.

    Testicular cancer

    It is also called a malignant neoplasm of the testis. Cancer usually occurs in the testicles when compared with another type of cancer it is rare. Symptoms include testicle enlargement, abdomen and groin pain, enlargement of breast and back pain


    Blastolem 50mg Injection Indication

    The Blastolem 50mg Injection is prescribed in the following indications as ovarian cancer, bladder cancer, and testicular cancer.  


    Mechanism of action of Blastolem 50mg Injection

    Blastolem 50mg Injection contains Cisplatin 50mg is an anti-cancer medication, a platinum coordination compound. It produces its action by inhibiting the synthesis of DNA, cross-links, and denatures the strands of DNA. This disrupts the function of DNA by binding to the DNA bases. It can also produce DNA intrastrand cross-linking and breakage and leads to cell death.


    How Blastolem 50mg Injection works

    Blastolem 50mg Injection contains Cisplatin 50mg is an anti-cancer medication, a platinum coordination compound. It produces its action by damaging the DNA and RNA of the cancer cells which inhibit the growth and multiplication of cancer cells.


    Blastolem 50mg Injection Contraindication

    • Do not take this medicine if you are allergic to Blastolem
    • It is contraindicated to use this medicine in patients with severe myelosuppression, bleeding, renal dysfunction, pregnancy, and lactation


    Blastolem 50mg Injection Side Effects

    • Leukopenia
    • Neutropenia
    • Nausea, vomiting
    • Anemia
    • Thrombocytopenia
    • Hair loss
    • Increased liver enzymes
    • Dehydration
    • Peripheral neuropathy


    FAQs for Blastolem 50mg Injection

    • Is Blastolem 50mg Injection safe?

    Yes, the use of this medicine is considered safe if you have taken the medicine as per the dose and duration advised by the doctor.

    • Can I stop using the Blastolem 50mg Injection immediately or do I have to slowly wean off the use?

    You should not withdraw the medicine immediately, you should taper the dose to avoid rebound effects.

    • Does Blastolem 50mg Injection cause hair loss?

    Yes, one of the common side effects of this medicine is hair loss. This will get treated once you stop the treatment.


    Precautions and general warning of Blastolem 50mg Injection

    Alcohol

    It is not clear that consuming alcohol is safe while you are receiving this medicine. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor

    Kidney Problem

    Therapy should be administered with caution in patients who are having a renal impairment. Adjust the dose as per the requirement. Kindly consult with your doctor.

    Liver Disease

    It is considered safe to use this medicine in patients who are with hepatic impairment. Kindly consult with your doctor.


    How to Take Blastolem 50mg Injection

    Blastolem 50mg Injection comes in a liquid solution as an intravenous. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Blastolem 50mg Injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.


    Use of Blastolem 50mg Injection in children

    It is considered safe to use this medicine in children. Kindly consult with your doctor.


    Use of Blastolem 50mg Injection in Elderly Patients

    Blastolem 50mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The use of this medicine may cause irritant
    • Avoid using aluminum needles
    • Therapy should be administered with caution in patients with renal impairment, hearing impairment, neuropathy, neuromuscular diseases
    • The use of this medicine may increase the risk of developing cumulative nephrotoxicity
    • Myelosuppression, leukemia, cardiac abnormalities, ocular toxicity, renal toxicity, and peripheral neuropathy was reported


    Talk to your doctor if

    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have a receiving any concomitant medication and disease
    • You develop shortness of breath


    General instructions

    Cisplatin 50mg is used to treat ovarian cancer, bladder cancer, and testicular cancer. It produces its action by damaging the DNA and RNA of the cancer cells which inhibit the growth and multiplication of cancer cells.


    Drug Interaction of Blastolem 50mg Injection

    Drug-Drug Interaction

    Tofacitinib

    Use alternative drug because the combination of this medicine either increase the toxicity of the other by immunosuppressive effect and it also increases the risk for developing an infection.

    Palifermin

    Use alternative drugs because the use of palifermin increases the toxicity of the cisplatin by increasing the severity and duration of oral mucositis

    Amikacin

    Therapy should be administered with caution because the combination of this medicine increases the nephrotoxicity and ototoxicity

    Dichlorphenamide

    Therapy should be administered with caution because the combination of this medicine decreases the serum potassium

    Peramivir

    Therapy should be administered with caution because the use of cisplatin increases the effect of peramivir by decreasing its renal clearance.

    Drug-Food Interaction

    No data available kindly consult with your doctor

    Drug-Disease Interaction

    Infections

    The use of this medicine is contraindicated in patients who are having infectious diseases because of their cytotoxic effect their induce myelosuppression.

    Myelosuppression

    Therapy should be administered with caution in patients with bone marrow suppression because the use of this medicine induces dose-related myelosuppression, leukopenia, thrombocytopenia, and anemia

    Renal dysfunction

    Therapy should be administered with caution in patients with renal impairment because the use of this medicine may cause nephrotoxicity

    Hemolytic anemia

    Therapy should be administered with caution in patients with a history of hemolytic syndromes because the use of this medicine may cause coomb’s hemolytic anemia


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 30°C at room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • Cisplatin 50mg is an anti-cancer medication, an alkylating agent
    • It is used to treat ovarian cancer, bladder cancer, and testicular cancer.
    • Do not withdraw the medicine without consulting with a doctor
    • Kindly avoid pregnancy while you are receiving this medicine
    • Kindly consult with your doctor if you have experienced shortness of breath, chest pain, loss of appetite, and dark urine while you are receiving this medicine


    References