Canmab 150mg Injection

Brand Name Canmab 150mg Injection
Salt Composition

Trastuzumab (150mg)

Strength 150mg
Product Form Injection
Pack 1 Injection in 1 Vial
Storage Store in a refrigerator (2 - 8°C). Do not freeze
Category

Anti-Cancer

SubCategory

Breast Cancer

Country of Origin India
Manufacturer

Biocon

Manufacturer/Marketer Address Biocon, 20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100
-3%
Canmab 150mg Injection,Trastuzumab 150mg,price,uses,side Effects - Drugcarts watermark
M.R.P : Rs.21430.50       Price : Rs.20787.58

You Save : Rs.642.92    Inclusive of all taxes

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1 Injection in 1 Vial

Availability : In Stock


    Medical Description of Canmab 150mg Injection

    Canmab 150mg Injection contains Trastuzumab 150mg used to treat breast cancer and gastric cancer that spreads to other parts of the body. It works by killing the cancer cells. It is used alone or in combination with other anti-cancer medications.


    Canmab 150mg Injection Uses

    It is used in the treatment of the following conditions breast cancer and gastric cancer


    Canmab 150mg Injection Benefits

    Breast cancer

    It is a type of cancer that forms in the breast cells. It is common among women. Symptoms include breast lump, change in breast size, redness, pitting of the skin, color change, and peeling surrounding the breast skin or nipple. This medicine helps to inhibit the multiplication of cancer cells.

    Gastric cancer

    It is an abnormal growth of cells that starts in the stomach. Stomach cancer is also called gastric cancer it will affect any part of your stomach. Symptoms include difficulty in swallowing, bloating, heartburn, indigestion, stomach pain, weight loss, and vomiting. This medicine helps to inhibit the multiplication of cancer cells.


    Canmab 150mg Injection Indication

    The Canmab 150mg Injection is prescribed in the following indications as

    • Breast cancer which is HER-2 overexpressing and metastatic type
    • Gastric cancers which are HER-2 overexpressing and metastatic type
    • Gastroesophageal junction adenocarcinoma which is a metastatic type


    Mechanism of action of Canmab 150mg Injection

    Canmab 150mg Injection contains Trastuzumab 150mg is an anti-cancer medication, a monoclonal antibody. It produces its action by inhibiting the growth and proliferation of abnormal cells that overexpress the human epidermal growth factor receptor (HER-2). Trastuzumab act as a mediator of antibody-dependent cellular toxicity. Thus, it inhibits the proliferation of abnormal cancer cells and induces apoptosis.


    How Canmab 150mg Injection works

    Canmab 150mg Injection contains Trastuzumab 150mg is an anti-cancer medication, a monoclonal antibody. It produces its action by inhibiting human epidermal growth factor receptor protein which is responsible for the proliferation of abnormal cells and induces apoptosis


    Canmab 150mg Injection Contraindication

    Do not take this medicine if you are allergic to Trastuzumab


    Canmab 150mg Injection Side Effects

    • Pain
    • Fever
    • Chills
    • Cough
    • Headache
    • Diarrhea
    • Vomiting
    • Abdominal pain
    • Back pain
    • Infection
    • Rash
    • Insomnia
    • Dizziness
    • Depression
    • Anemia
    • Cardiac failure
    • Thrombocytopenia


    FAQs for Canmab 150mg Injection

    • Does Canmab 150mg Injection cause hair loss?

    Yes, one of the common side effects of this medicine is hair loss. Kindly consult with your doctor if your symptoms even persist after withdrawal of the medicines.

    • How frequently heart investigations are required?

    It is better to perform a heart investigation before initiating the treatment and it should be repeated 3 months during treatment or every 6 months after the discontinuation of the therapy.

    • Can I stop using Canmab 150mg Injection immediately or do I have to slowly wean off the use?

    You should not withdraw the medicine immediately, you should taper the dose to avoid rebound effects.


    Precautions and general warning of Canmab 150mg Injection

    Alcohol

    It is considered unsafe to consume alcohol while you are receiving this medicine. Kindly consult with your doctor

    Driving or operating machinery

    It is not clear that the use of this medicine will alter the ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor

    Kidney Problem

    It is considered safe to use this medicine in patients who are having a renal impairment. Kindly consult with your doctor.

    Liver Disease

    Limited information is available regarding the use of this medicine in patients with hepatic impairment. Kindly consult with your doctor.


    How to Take Canmab 150mg Injection

    Canmab 150mg Injection comes in a liquid solution as an intravenous and subcutaneous. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Canmab 150mg Injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.


    Use of Canmab 150mg Injection in children

    Safety and efficacy were not established in children. Kindly consult with your doctor.


    Use of Canmab 150mg Injection in Elderly Patients

    Canmab 150mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • Cardiomyopathy, infusion reaction, and pulmonary toxicity was reported
    • Therapy should be administered with caution in patients with cardiac diseases, decreased ejection fraction, pulmonary diseases, and in elderly
    • Kindly avoid using this medicine while you are pregnant it may cause fetal harm
    • The use of this medicine may cause tumor lysis syndrome


    Talk to your doctor if

    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have a receiving any concomitant medication and disease
    • You develop shortness of breath


    General instructions

    Trastuzumab 150mg is used to treat breast cancer and gastric cancer. It produces its action by inhibiting human epidermal growth factor receptor protein which is responsible for the proliferation of abnormal cells and induces apoptosis


    Drug Interaction of Canmab 150mg Injection

    Drug-Drug Interaction

     Doxorubicin

    Use alternative drugs because the combination of this medicine either increases the toxicity of the other by an unknown mechanism.

    Methotrexate

    Therapy should be administered with caution because the combination of this medicine either increases the toxicity of the other by immunosuppressive effect and it also increases the risk of infection

    Drug-Food Interaction

    No data is available kindly consult with your doctor.

    Drug-Disease Interaction

    Pulmonary toxicity

    Therapy should be administered with caution because the use of this medicine may cause pulmonary toxicity including dyspnea, interstitial pneumonitis, pulmonary infiltrates, non-cardiogenic edema, pulmonary insufficiency, and hypoxia.

    Congestive heart failure

    Therapy should be administered with caution in patients who are having a history of heart diseases because the use of this medicine decreases the left ventricular ejection fraction.

    Peripheral neuropathy

    Therapy should be administered with caution because the use of HER2 inhibitor leads to develop peripheral neuropathy


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 30°C in a refrigerator.
    • Do not freeze
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • Trastuzumab 150mg is an anti-cancer medication, a monoclonal antibody
    • It is used to treat breast and gastric cancer
    • Kindly avoid taking this medicine while you are pregnant
    • Avoid consuming alcohol while you are receiving this medicine because it may increase the risk of developing serious side effects.