Canmab 440mg Injection
Brand Name | Canmab 440mg Injection |
Salt Composition |
Trastuzumab (440mg) |
Strength | 440mg |
Product Form | Injection |
Pack | 1 Injection in 1 Vial |
Storage | Store in a refrigerator (2 - 8°C). Do not freeze |
Category |
Anti-Cancer |
SubCategory |
Breast Cancer |
Country of Origin | India |
Manufacturer |
Biocon |
Manufacturer/Marketer Address | Biocon, 20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100 |
You Save : Rs.599.82 Inclusive of all taxes
- Breast cancer which is HER-2 overexpressing and metastatic type
- Gastric cancers which are HER-2 overexpressing and metastatic type
- Gastroesophageal junction adenocarcinoma which is a metastatic type
- Pain
- Fever
- Chills
- Cough
- Headache
- Diarrhea
- Vomiting
- Abdominal pain
- Back pain
- Infection
- Rash
- Insomnia
- Dizziness
- Depression
- Anemia
- Cardiac failure
- Thrombocytopenia
- Does Canmab 440mg Injection cause hair loss?
- How frequently heart investigations are required?
- Can I stop using Canmab 440mg Injection immediately or do I have to slowly wean off the use?
- Cardiomyopathy, infusion reaction, and pulmonary toxicity was reported
- Therapy should be administered with caution in patients with cardiac diseases, decreased ejection fraction, pulmonary diseases, and in elderly
- Kindly avoid using this medicine while you are pregnant it may cause fetal harm
- The use of this medicine may cause tumor lysis syndrome
- You are not responding to the treatment
- You have experienced any allergic reaction like rashes and itching
- You have a receiving any concomitant medication and disease
- You develop shortness of breath
- Stored at 30°C in a refrigerator.
- Do not freeze
- Protect from light and heat.
- Keep away from children and pets. Otherwise, it becomes toxic to them.
- Disposed of properly in a suitable bag.
- Trastuzumab 440mg is an anti-cancer medication, a monoclonal antibody
- It is used to treat breast and gastric cancer
- Kindly avoid taking this medicine while you are pregnant
- Avoid consuming alcohol while you are receiving this medicine because it may increase the risk of developing serious side effects.
Medical Description of Canmab 440mg Injection
Canmab 440mg Injection contains Trastuzumab 440mg used to treat breast cancer and gastric cancer that spreads to other parts of the body. It works by killing the cancer cells. It is used alone or in combination with other anti-cancer medications.
Canmab 440mg Injection Uses
It is used in the treatment of the following conditions breast cancer and gastric cancer
Canmab 440mg Injection Benefits
Breast cancer
It is a type of cancer that forms in the breast cells. It is common among women. Symptoms include breast lump, change in breast size, redness, pitting of the skin, color change, and peeling surrounding the breast skin or nipple. This medicine helps to inhibit the multiplication of cancer cells.
Gastric cancer
It is an abnormal growth of cells that starts in the stomach. Stomach cancer is also called gastric cancer it will affect any part of your stomach. Symptoms include difficulty in swallowing, bloating, heartburn, indigestion, stomach pain, weight loss, and vomiting. This medicine helps to inhibit the multiplication of cancer cells.
Canmab 440mg Injection Indication
The Canmab 440mg Injection is prescribed in the following indications as
Mechanism of action of Canmab 440mg Injection
Canmab 440mg Injection contains Trastuzumab 440mg is an anti-cancer medication, a monoclonal antibody. It produces its action by inhibiting the growth and proliferation of abnormal cells that overexpress the human epidermal growth factor receptor (HER-2). Trastuzumab act as a mediator of antibody-dependent cellular toxicity. Thus, it inhibits the proliferation of abnormal cancer cells and induces apoptosis.
How Canmab 440mg Injection works
Canmab 440mg Injection contains Trastuzumab 440mg is an anti-cancer medication, a monoclonal antibody. It produces its action by inhibiting human epidermal growth factor receptor protein which is responsible for the proliferation of abnormal cells and induces apoptosis
Canmab 440mg Injection Contraindication
Do not take this medicine if you are allergic to Trastuzumab
Canmab 440mg Injection Side Effects
FAQs for Canmab 440mg Injection
Yes, one of the common side effects of this medicine is hair loss. Kindly consult with your doctor if your symptoms even persist after withdrawal of the medicines.
It is better to perform a heart investigation before initiating the treatment and it should be repeated 3 months during treatment or every 6 months after the discontinuation of the therapy.
You should not withdraw the medicine immediately, you should taper the dose to avoid rebound effects.
Precautions and general warning of Canmab 440mg Injection
Alcohol
It is considered unsafe to consume alcohol while you are receiving this medicine. Kindly consult with your doctor
Driving or operating machinery
It is not clear that the use of this medicine will alter the ability to drive. Kindly consult with your doctor.
Pregnancy
The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor
Breast Feeding
The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor
Kidney Problem
It is considered safe to use this medicine in patients who are having a renal impairment. Kindly consult with your doctor.
Liver Disease
Limited information is available regarding the use of this medicine in patients with hepatic impairment. Kindly consult with your doctor.
How to Take Canmab 440mg Injection
Canmab 440mg Injection comes in a liquid solution as an intravenous and subcutaneous. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.
Use of Canmab 440mg Injection in Adult
It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.
Use of Canmab 440mg Injection in children
Safety and efficacy were not established in children. Kindly consult with your doctor.
Use of Canmab 440mg Injection in Elderly Patients
Canmab 440mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.
Other general warnings
Talk to your doctor if
General instructions
Trastuzumab 440mg is used to treat breast cancer and gastric cancer. It produces its action by inhibiting human epidermal growth factor receptor protein which is responsible for the proliferation of abnormal cells and induces apoptosis
Drug Interaction of Canmab 440mg Injection
Drug-Drug Interaction
Doxorubicin
Use alternative drugs because the combination of this medicine either increases the toxicity of the other by an unknown mechanism.
Methotrexate
Therapy should be administered with caution because the combination of this medicine either increases the toxicity of the other by immunosuppressive effect and it also increases the risk of infection
Drug-Food Interaction
No data is available kindly consult with your doctor.
Drug-Disease Interaction
Pulmonary toxicity
Therapy should be administered with caution because the use of this medicine may cause pulmonary toxicity including dyspnea, interstitial pneumonitis, pulmonary infiltrates, non-cardiogenic edema, pulmonary insufficiency, and hypoxia.
Congestive heart failure
Therapy should be administered with caution in patients who are having a history of heart diseases because the use of this medicine decreases the left ventricular ejection fraction.
Peripheral neuropathy
Therapy should be administered with caution because the use of HER2 inhibitor leads to develop peripheral neuropathy
Over Dose
Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.
Missed Dose
Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).
Storage and Disposal
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