Cetalic TZ 1000mg/125mg Injection

Cetalic TZ 1000mg/125mg Injection contains Ceftazidime 1000mg and Tazobactum 125mg used to treat bacterial infections such as bacterial meningitis, septicemia, intra-abdominal infections, community-acquired pneumonia, bone and joint infections, gonorrhea, urinary tract infection, skin and soft tissue infections, pelvic inflammatory infection, and bacterial endocarditis. Mainly this medicine targets infection of the lungs, bone, joint, heart, stomach, intestine, skin, and urinary tract. Ceftazidime 1000mg is an antibiotic that helps to inhibit the growth of bacteria and it also helps to prevent the infection that occurs during surgery. Tazobactam 125mg is a β lactamase inhibitor. It should be given with antibiotic, which works by inhibiting the β lactamase enzyme (destroys the action of antibiotics) produced by bacteria.  The combination of this medicine helps to fight against microbes and also prevents the growth of bacteria. This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial and parasitic infections.

It is used in the treatment of the following conditions as bacterial meningitis, septicemia, intra-abdominal infections, community-acquired pneumonia, bone, and joint infections, gonorrhea, urinary tract infection, skin and soft tissue infections, pelvic inflammatory infection, and bacterial endocarditis.

Bacterial infections

Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

Urinary tract infection

It is a type of infection that affects the urethra, kidneys, and bladder. It is caused by Escherichia coli (E.coli). Symptoms include abdominal pain, frequent urination, dysuria, blood in urine, foul-smell while urinating

Gonorrhea

It is a sexually transmitted infection caused by bacteria called Neisseria gonorrhoeae. It affects both males and females. Symptoms include thick discharge from the penis, increased vaginal discharge, pain while urinating, anal itching, discharge, and spotting between menstrual bleeding.

Bone and joint infection

Bone infection is also called Osteomyelitis. It is caused by bacteria called staphylococcus which travels through the bloodstream to the weak area in a bone. Symptoms include fever, pain, fatigue, tenderness, redness, and warmth.

Community-acquired pneumonia

It is a type of pneumonia which usually found in people who are not admitted to the hospital recently. It is caused by bacteria called Streptococcus pneumonia, Haemophilus influenza, and Mycoplasma pneumonia. Symptoms include chest pain, cough, shortness of breath, sputum, fever, and abdominal pain.

Skin infection

It is usually caused by bacteria, fungi, viruses, and parasites. Common skin infection includes cellulitis, impetigo. Symptoms include red skin, blisters, swelling, pain, red spots, and tenderness

Pelvic inflammatory diseases

It is also called pelvic infection. It is an infection of the female reproductive organs that occur in the female upper genital tract. It usually occurs when sexually transmitted bacteria spread via the vagina to the uterus, fallopian tubes, and ovaries. Symptoms include pain in the pelvic region, abnormal vaginal discharge, uterine bleeding, pain during intercourse, fever, and difficulty in urination.

Bacterial meningitis

Infection and inflammation to the meninges (in the brain) caused by bacteria called bacterial meningitis. This medicine is used to treat this bacterial infection.

Bacterial septicemia

Infection of the blood caused by bacteria leads to increased toxins in the bloodstream passes to the entire body develops organ damage. This medicine is used to treat this bacterial infection.

Skin and soft tissue infections

Infections such as cellulitis wound infection and cutaneous abscess caused by Streptococcus pyogenes and Staphylococcus aureus bacteria are related to skin and skin structure infections, treated by this medicine.

Bacterial endocarditis

Infection in the inner lining of the heart is caused by bacteria called bacterial endocarditis. This injection is used to treat bacterial infections.

The Cetalic TZ 1000mg/125mg Injection is prescribed in the following indications as bacterial meningitis, septicemia, intra-abdominal infections, community-acquired pneumonia, bone and joint infections, gonorrhea, urinary tract infection, skin and soft tissue infections, pelvic inflammatory infection, and bacterial endocarditis.

The Cetalic TZ 1000mg/125mg Injection contains Ceftazidime 1000mg and Tazobactum 125mg is a combination of two medicines. Ceftazidime 1000mg is a third-generation cephalosporin antibiotic that produces its action by preventing bacterial cell wall synthesis which is essential for the growth of bacteria and also prevents the spreading of infections. Tazobactam 125mg is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of the antibiotic. The combination with Tazobactum helps to reduce the development of resistance and increase the action of Ceftazidime against bacteria.

The Cetalic TZ 1000mg/125mg Injection contains Ceftazidime 1000mg and Tazobactum 125mg is a combination of two medicines. Ceftazidime 1000mg is a third-generation cephalosporin antibiotic that produces its action by preventing bacterial cell wall synthesis which is essential for the growth of bacteria and also prevents the spreading of infections. Tazobactam 125mg is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of the antibiotic. The combination with Tazobactum helps to reduce the development of resistance and increase the action of Ceftazidime against bacteria.

• Do not take this medicine if you are allergic to Ceftazidime and Tazobactam

• Abdominal pain
• Angioedema
• Dizziness
• Phlebitis
• Thrombocytosis
• Injection site pain
• Immune hypersensitivity reaction
• Diarrhea
• Eosinophils
• Hallucinations
• Leukopenia
• Metallic taste
• Myoclonia
• Photosensitivity
• Seizures
• Thrombocytopenia

• Is Cetalic TZ 1000mg/125mg Injection effective?

It is considered effective if you have taken the medicine as per the dose and duration prescribed by the doctor. Do not withdraw the medicine if you feel better, it may worsen the condition

• What if I do not get better after using the Cetalic TZ 1000mg/125mg Injection?

If you do not feel better after completing the full course of treatment kindly inform your doctor.

• What organism does Cetalic TZ 1000mg/125mg Injection cover?

This medicine is effective against Pseudomonas anaerobes and Staphylococcus bacteria and it is also effective against Methicillin-resistant Staphylococcus aureus.

Alcohol

The use of alcohol does not produce harmful effects while you are receiving this treatment. Kindly consult with your doctor.

Driving or operating machinery

It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

Pregnancy

The use of this medicine is considered safe during pregnancy because it does not produce a harmful effect on the developing fetus. Kindly consult with your doctor

Breast Feeding

The use of this medicine is considered safe during breastfeeding because it does not excrete via breastmilk. Kindly consult with your doctor

Kidney Problem

The therapy should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

Liver Disease

The therapy should be used with caution in patients with hepatic impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

Cetalic TZ 1000mg/125mg Injection comes in a liquid solution as an intravenous injection. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.

It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.

Cetalic TZ 1000mg/125mg Injection is not prescribed in children who are below 1 month old. Kindly consult with your doctor.

Cetalic TZ 1000mg/125mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.

• Therapy should be administered with caution in patients who are having a history of seizure disorder
• There will be an elevated international normalized ratio in patients who are in prolonged treatment.
• Kindly adjust the dose in renal impairment patients
• Therapy should be administered with caution in patients who are allergic to penicillin
• Long-term use may cause a bacterial or fungal overgrowth of a nonsusceptible organism
• The use of this medicine may cause Clostridium difficile-associated diarrhea
• The use of this medicine may increase the risk of developing neurotoxicity
• Therapy should be administered with caution in patients who are having electrolyte imbalance.

             Diarrhea

• This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. It leads to worsening the patient’s health condition. Better to take probiotics with this medicine to avoid diarrhea.

              Antibiotic resistance

• Finish the complete course of antibiotics even if you feel better. Otherwise, it will lead to Antibiotic resistance (the bacteria may be resistant to antibiotics)

• You have a history of gastrointestinal disease
• You are not responding to the treatment
• You have experienced any allergic reaction like rashes and itching

Ceftazidime 1000mg and Tazobactum 125mg are used to treat bacterial infections such as bacterial meningitis, septicemia, intra-abdominal infections, community-acquired pneumonia, bone and joint infections, gonorrhea, urinary tract infection, skin and soft tissue infections, pelvic inflammatory infection, and bacterial endocarditis.

Ceftazidime 1000mg is a third-generation cephalosporin antibiotic that produces its action by preventing bacterial cell wall synthesis which is essential for the growth of bacteria and also prevents the spreading of infections. Tazobactam 125mg is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of Ceftazidime. The combination with Tazobactum helps to reduce the development of resistance and increase the action of Ceftazidime against bacteria.

Drug-Drug Interaction

BCG vaccine live                            

The use of this drug is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism

Cholera vaccine

Use alternative drugs, because the use of the cholera vaccine with antibiotics may activate the vaccine strain. So, avoid receiving this combination of medicines before 14 days of vaccination

Estradiol

Therapy should be administered with caution because the use of Ceftazidime will decrease the effect of estradiol by altering the intestinal flora and it also lowers the risk of contraceptive failure

Warfarin

Therapy should be administered with caution because the combination of this drug may decrease the vitamin K producing intestinal flora and increase the INR level after a few days

Furosemide

The use of Ceftazidime increase the toxicity of furosemide by pharmacodynamic synergism and it also increases the risk of developing nephrotoxicity

Aspirin

The use of Ceftazidime will increase the effect of aspirin by acidic drug competition for renal tubular clearance.

Drug-Food Interaction

The food may increase the effect of the drug in your body so it is advised to take this injection with food to increase the absorption

Drug-Disease Interaction

Colitis

This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This drug should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient’s health condition.

Kidney disease

This medicine is filtered by the kidneys and passes through the urine. Then it leads to the risk of kidney damage. It should be used with caution in a patient with kidney disease. Inform your doctor and then take. Based on the patient's condition, dose adjustment is needed.

Seizures

Using this medicine is needs caution in patients with seizures or fits. Inform the doctor, then will do dose adjustment if necessary to take this medicine with seizure medications.

Lab interactions

This medicine gives a false positive test for Coombs test and Urine ketones test.

Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.

Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).

• Stored at 10-30°C room temperature.
• Protect from light and heat.
• Keep away from children and pets. Otherwise, it becomes toxic to them.
• Disposed of properly in a suitable bag.

Cetalic TZ 1000mg/125mg Injection contains Ceftazidime 1000mg and Tazobactum 125mg used to treat bacterial infections such as bacterial meningitis, septicemia, intra-abdominal infections, community-acquired pneumonia, bone and joint infections, gonorrhea, urinary tract infection, skin and soft tissue infections, pelvic inflammatory infection, and bacterial endocarditis. Mainly this medicine targets infection of the lungs, bone, joint, heart, stomach, intestine, skin, and urinary tract.

Ceftazidime 1000mg is an antibiotic that helps to inhibit the growth of bacteria and it also helps to prevent the infection that occurs during surgery. Tazobactam 125mg is a β lactamase inhibitor. It should be given with antibiotic, which works by inhibiting the β lactamase enzyme(destroys the action of antibiotics) produced by bacteria.  The combination of this medicine helps to fight against microbes and also prevents the growth of bacteria.

This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial infections.