Codifab 400mg Tablet

Brand Name Codifab 400mg Tablet
Salt Composition

Favipiravir (400mg)

Strength 400mg
Product Form Tablet
Storage Store below 30°C
Category

Antiviral

SubCategory

anti-viral

Country of Origin India
Manufacturer

Akumentis Healthcare Ltd

Manufacturer/Marketer Address Akumentis Healthcare Ltd, 204, 2nd Floor, G-Corp Tech Park, Kasarvadavali, Near Hypercity, Ghodbandar Road, Thane (West) - 400615. ,Maharashtra, India.
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M.R.P : Rs.1090.00    

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Availability : In Stock


    Medical Description of Codifab 400mg Tablet

    Codifab contains its active substance called Favipiravir. Favipiravir is an antiretroviral medicine used in the treatment of influenza infection. It is an RNA polymerase inhibitor. It is used in the treatment of SARS COV-2 infection in adults with mild to moderate illness. Favipiravir is not recommended in children.


    Codifab 400mg Tablet Uses

    Codifab is used to treat adults and children above 18 years of age who are infected by viral infections like remerging influenza, ebola and covid-19 infection.


    Codifab 400mg Tablet Benefits

    Codifab is used to treat COVID-19 infection which is mild or moderate form. It is an RNA polymerase inhibitor & not recommended for use in children less than 18 years of age due to the increased risk of serious side effects.


    Codifab 400mg Tablet Indication

    Codifab is indicated in case of viral infections like remerging influenza, ebola and covid-19 infection and recommended for ages above 18 years 


    Mechanism of action of Codifab 400mg Tablet

    Codifab ( Favipiravir )  is an RNA polymerase inhibitor.  It inhibits the replication of the viral genome and acts as an RNA dependant RNA polymerase inhibitor. It also incorporates into RNA strands of virions thus prevents elongation and proliferation of virions. Favipiravir thus prevents the formation of mature virus particles into infectious virions that spreads the infection. Thus, inhibits the replication of the virus and treats illness.


    How Codifab 400mg Tablet works

    Favipiravir is an RNA polymerase inhibitor. It inhibits the action of RNA proliferation and maturation of RNA of virions thereby prevents the formation of mature virus particles. Thus, controls the viral infection and improves immunity


    Codifab 400mg Tablet Contraindication

    If you are allergic to Codifab or its constituents.

    If you have liver diseases

    If you have kidney disease

    If you are lactating

    If you are pregnant


    Codifab 400mg Tablet Side Effects

    • Shock
    • Anaphylaxis
    • Pneumonia
    • Fulminant hepatitis
    • Liver disorders
    • Jaundice
    • Toxic epidermal necrosis
    • Stevens-Johnson syndrome
    • Acute kidney injury
    • Leukopenia
    • Neutropenia
    • Thrombocytopenia
    • Delirium
    • Hallucination
    • Convulsion
    • Haemorrhagic colitis


    FAQs for Codifab 400mg Tablet

    Is Codifab safe during pregnancy?

    No, taking Codifab during pregnancy is not recommended. Consult your physician.

    Can Codifab be taken while breastfeeding?

    No, taking Codifab is not recommended during breastfeeding. Consult your physician.

    Can Codifab be taken while alcohol consumption?

    The interaction is unknown but Codifab causes psychiatric side effects. Thus, consult your physician.

    Can I take a drive or operate heavy machinery while on Codifab?

    Codifab causes psychiatric side effects thus caution is used while driving or operating machinery.


    Precautions and general warning of Codifab 400mg Tablet

    Alcohol

    Codifab generally causes psychiatric side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

    Driving or operating machinery

    It is preferred to drive or operate heavy machinery with caution as Codifab causes psychiatric side effects. For further queries, consult your physician.

    Pregnancy

    The use of Codifab 400mg tablet is not recommended during pregnancy.

    Breast Feeding

    The use of Codifab tablet during breastfeeding is not recommended.

    Kidney Problem

    Monitor kidney function before and during therapy, especially in patients with other kidney disorders

    Liver Disease

    Monitor liver function before and during therapy, especially in patients with other liver disorders


    How to Take Codifab 400mg Tablet

    Codifab is taken orally with or without food.

    It must be taken at the same time once a day as prescribed by your physician.

    It must be taken as a whole do not crush the tablet

    After therapy has been initiated, do not take more or less of this drug than prescribed or stop taking it without your physicians’ approval. Skipping or changing your dose of Favipiravir without approval may cause the amount of the virus to increase making the infection more difficult to treat, or worsen side effects.


    Use of Codifab 400mg Tablet in Adult

    If you are pregnant or breastfeeding inform your physician as Favipiravir is not advisable.

    The recommended dosage for Codifab is 1,800 mg on day 1 followed by 800mg per day for the next 14 days

    Regular monitoring of liver and kidney function is advised


    Use of Codifab 400mg Tablet in children

     Not recommended in children


    Use of Codifab 400mg Tablet in Elderly Patients

    This tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.


    Other general warnings

    Skin reactions - It can be mild to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.

    Gout


    Talk to your doctor if

    If you have any allergy

    If you have a liver problem

    If you have a kidney problem

    If you are pregnant or breastfeeding


    General instructions

    It should be taken orally with or without food as prescribed dosage at a specific time regularly.


    Drug Interaction of Codifab 400mg Tablet

    Drug-Drug Interaction

    side effects are increased by Cimetidine, Ranitidine, Thiamine

    serum concentration is decreased by St. John's Wort, Phenytoin, Carbamazepine

    serum concentration is increased by Atenolol, Indomethacin, Folic acid

    Drug-Food Interaction

    Codifab can be safely taken with any type of food, if doubts arise kindly refer to your physician. It generally causes side effects thus it is advised not to be taken with alcohol. It is preferred to drive or operate heavy machinery with caution while using this medication

    Drug-Disease Interaction

    • Liver disorders – used with caution in severe liver diseases. Consult a physician before use
    • Kidney disorders – used with caution in severe kidney diseases. Consult a physician before use
    • Cardiac disorders – used with caution in hypotension and MI. Consult a physician before use
    • Respiratory disorders – used with caution in respiratory distress. Consult a physician before use
    • Blood disorders – used with caution in myelosuppression diseases. Consult a physician before use.
    • Bone disorders – used with caution in gout. Consult a physician before use.


    Over Dose

    Contact your doctor, Pharmacist or Nurse immediately.


    Missed Dose

    If you take twice a day dosage, then the missed dosage if you notice within 6 hours. If it is more than 6 hours, then skip the dosage and take the next doses as usual. Don’t take a double dose for a forgotten dose


    Storage and Disposal

    Keep the medication out of children’s reach

    Keep the medication away from pets

    Once expired dispose immediately

    Store at 30°C


    Fast Tag

    Codifab contains its active substance called Favipiravir.

    It is an RNA polymerase inhibitor.

    It is used to control and treat SARS COV 2 infection (influenza, ebola and covid-19)

    Do not use this medication while pregnancy and lactation period.

    Don’t use this medication with liver disease and kidney diseases