Eliquis 5mg Tablet

Brand Name Eliquis 5mg Tablet
Salt Composition Apixaban (5mg)
Strength 5mg
Product Form Tablet
Storage Store at room temperature (10-30°C)
Category anti-coagulant
Country of Origin Italy
Manufacturer Pfizer Ltd
Manufacturer/Marketer AddressPfizer Ltd, The Capital, 1802, 18th Floor, Plot No. C-70, 'G' Block, Bandra Kurla Complex, Bandra East, Mumbai - 400051
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Eliquis 5mg Tablet, Apixaban 5mg, price, uses, side effects - Drugcarts watermark
M.R.P : Rs.1450.00       Price : Rs.1160.00

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    Medical Description of Eliquis 5mg Tablet

    Eliquis 5mg tablet contains apixaban 5mg its a class of medication called factor Xa inhibitors which are meant for oral use only. It is an anticoagulant, used in the treatment of stroke prophylaxis with atrial fibrillation, deep vein thrombosis, and pulmonary embolism by inhibiting the action of a certain natural substance that helps in the formation of blood clots in the body.


    Eliquis 5mg Tablet Uses

    Eliquis 5mg Tablet is used in the treatment and prevention of blood clots


    Eliquis 5mg Tablet Benefits

    Eliquis 5mg Tablet is used in the treatment and prevention for the following condition like

    Atrial fibrillation:

    It causes irregular heart rhythm which results in poor blood flow and increases the risk of stroke. It usually occurs if you have hypertension, a history of myocardial infarction, coronary artery disease, heart surgery. The common cause of atrial fibrillation is damage to the structure of the heart. Symptoms include palpitation, weakness, fatigue, lightheadedness, dizziness, chest pain, and shortness of breath.

    Deep vein thrombosis:

    It usually occurs when a blood clot forms in one or more veins in your body. It is caused by a genetic condition, injury, surgery, pregnancy, age, overweight, hormone therapy, and pacemaker. Symptoms include swelling in the arm and leg, pain in the leg, skin discolouration.

    Pulmonary embolism:

    It usually occurs when the blood clot that forms in the artery of your lungs and travels to other parts of the body. Symptoms include shortness of breath, chest pain, cough, dizziness, excessive sweating, irregular heartbeat, and skin discolouration.


    Eliquis 5mg Tablet Indication

    Eliquis 5mg Tablet is used in the treatment of stroke prophylaxis with atrial fibrillation, deep vein thrombosis, and pulmonary embolism by inhibiting the action of a certain natural substance that helps in the formation of blood clots in the body.


    Mechanism of action of Eliquis 5mg Tablet

    Apixaban is a factor Xa inhibitor that produces its action by inhibiting the platelet activation and reversibly inhibiting the active site of factor Xa without a cofactor and it also inhibits the free and clot-bound factor Xa and the activity of prothrombinase and it indirectly inhibits the aggregation of platelet which is induced by thrombin. Blood coagulation depends upon the activation of factor X to factor Xa through the intrinsic and extrinsic pathways which play an important role in the blood coagulation cascade.


    How Eliquis 5mg Tablet works

    Apixaban is a factor Xa inhibitor that produces its action by inhibiting the platelet activation and reversibly inhibiting the active site of factor Xa without a cofactor and it also inhibits the free and clot-bound factor Xa and the activity of prothrombinase and it indirectly inhibits the aggregation of platelet which is induced by thrombin. Blood coagulation depends upon the activation of factor X to factor Xa through the intrinsic and extrinsic pathways which play an important role in the blood coagulation cascade.


    Eliquis 5mg Tablet Contraindication

    If the patient is allergic to the composition of the medicines

    It is contraindicated in patients with active pathological bleed


    Eliquis 5mg Tablet Side Effects

    • Postural hypotension
    • Thrombocytopenia
    • Respiratory disorders
    • Haemorrhage
    • Hematuria
    • Hypersensitivity reactions
    • Syncope


    FAQs for Eliquis 5mg Tablet

    What if I miss a dose of Eliquis 5mg (Apixaban 5mg) tablet?

    If you missed the dose take the medicine as soon as you remember. If it is time for a subsequent dose skip the missed dose and continue with a daily dose

    What is the Eliquis 5mg tablet used for?

    Eliquis 5mg tablet contains apixaban is in a class of medication called factor Xa inhibitors which are meant for oral use only. It is used in the treatment of stroke prophylaxis with atrial fibrillation, deep vein thrombosis, and pulmonary embolism by inhibiting the action of a certain natural substance that helps in the formation of blood clots in the body.

    Do I need to stop the Eliquis 5mg tablet before surgery?

    Before surgery kindly consult with your doctor whether you have to stop the treatment or not. It depends upon the type of procedure you are undergoing


    Precautions and general warning of Eliquis 5mg Tablet

    Alcohol

    The use of alcohol may affect the effectiveness of the drug. Kindly consult with your doctor

    Driving or operating machinery

    It is safe to drive or operate heavy machinery while receiving this medication. Kindly consult with your doctor.

    Pregnancy

    It is considered safe to use this medicine in patients during pregnancy it does not produce a harmful effect on the fetus. Kindly consult with your doctor.

    Breast Feeding

    It is considered unsafe to use this medicine in patients during breastfeeding it may excrete via breast milk. Kindly consult with your doctor.

    Kidney Problem

    Eliquis 5mg tablet should be administered with caution in patients with renal impairment. Kindly consult with your doctor.

    Liver Disease

    Eliquis 5mg tablet should be administered with caution in patients with hepatic impairment. Kindly consult with your doctor.


    How to Take Eliquis 5mg Tablet

    The tablet is taken orally with or without food. You should not chew, cut or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Eliquis 5mg Tablet in Adult

    It is considered safe to use this medicine in an adult patient if it is prescribed by your doctor


    Use of Eliquis 5mg Tablet in children

    Information regarding the use of this medicine in children is not available. Kindly consult with your doctor.


    Use of Eliquis 5mg Tablet in Elderly Patients

    It is considered safe to use this medicine in an elderly patient if it is prescribed by your doctor


    Other general warnings

    The use of this drug may increase the risk of thrombotic events, epidural and spinal hematoma

    The use of this drug may prolong the prothrombin time

    The use of this drug increases the risk of bleeding

    It is not recommended as an alternative to unfractionated heparin for the initial treatment of pulmonary embolism.


    Talk to your doctor if

    If the patient is allergic to the composition of the medicines

    If you’re using any concomitant medications

    If you’re not responding to the corresponding treatment


    General instructions

    Apixaban should be taken at the same time every day. Take this medicine as per your doctor prescription. Do not take the medicine without consulting with the doctor. Follow the dose and duration as per the doctor’s advice do not consume more or less dose than prescribed by the doctor.


    Drug Interaction of Eliquis 5mg Tablet

    Drug-Drug Interaction

    Betrixaban + Apixaban

    The use of this drug is contraindicated because the combination of this drug either increases the effect of the other by anticoagulation.

    Carbamazepine + Apixaban

    The use of this drug is contraindicated because the use of carbamazepine will decrease the effect of apixaban by affecting patient hepatic and intestinal enzyme metabolism.

    Defibrotide + Apixaban

    The use of this drug is contraindicated because the use of defibrotide increases the effect of apixaban by pharmacodynamic synergism.

    Warfarin + Apixaban

    The use of this drug is contraindicated because the combination of this drug increases the effect of anticoagulation.

    Enoxaparin + Apixaban

    Use alternative drugs because the combination of this drug increases the effect of anticoagulation.

    Berotralstat + Apixaban

    Therapy should be administered with caution because the use of berotralstat will increase the effect of apixaban by P-glycoprotein efflux transporter.

    Drug-Food Interaction

    Information regarding the food interaction is not available. Kindly consult with your doctor.

    Drug-Disease Interaction

    Bleeding:

    Therapy should be administered with caution in patients who are at increased risk for developing bleeding. The use of apixaban is contraindicated in patients with active pathological bleeding because it may increase the risk of thrombotic events, and bleeding.

    Hepatic impairment:

    The use of factor Xa inhibitor is not recommended in patients with moderate and severe hepatic impairment because it may increase the risk of bleeding.

    Valvular heart disease:

    The safety and efficacy are not studied in patients with prosthetic heart valves. The use of apixaban is not recommended in patients with prosthetic heart valves.


    Over Dose

    Consuming more quantity than the prescribed dose may cause an overdose. Kindly use the medicine as per you’re doctor advice


    Missed Dose

    If you missed the dose take the medicine as soon as you remember. If it is time for a subsequent dose skip the missed dose and continue with a daily dose


    Storage and Disposal

    Store the drugs in a closed container at room temperature, and keep the medicines away from heat, moisture, and direct daylight

    Do not keep the medicine reaching out to children’s

    Do not keep outdated medicine

    Ask your doctor or pharmacist the way to eliminate the medicine that’s not in use

    Store below 30°C


    Fast Tag

    Apixaban is in a class of medication called factor Xa inhibitor (anticoagulant)

    The drug is employed in the treatment of stroke prophylaxis with atrial fibrillation, deep vein thrombosis, and pulmonary embolism

    The tablet is taken orally by mouth with or without food

    Do not use this medicine if the patient is allergic to the composition of the medicine