Entaliv 0.5mg Tablet

Entaliv 0.5mg Tablet contains its active substance called Entecavir. Entecavir is an antiviral medicine used in the treatment of chronic hepatitis B infection. It is a guanine nucleoside analogue. It is used in compensated and decompensated liver diseases.

Entaliv 0.5mg Tablet is used to treat adults and children above 2 years of age who are infected by Hepatitis B virus. Entaliv 0.5mg Tablet should not be taken separately if you are HIV positive. Entaliv 0.5mg Tablet can be taken with other anti-HIV medications. Entaliv 0.5mg Tablet can be used in cases with compensated and decompensated liver diseases.

Entaliv 0.5mg Tablet is used to treat chronic hepatitis B infection who have compensated and decompensated liver disease. Entaliv 0.5mg Tablet is guanine nucleoside analogue. Entaliv 0.5mg Tablet is not a cure for HIV infection, it is used to treat chronic HBV. Entaliv 0.5mg Tablet is not recommended for use in children less than 2 years of age due to the increased risk of serious side effects.

Entaliv 0.5mg Tablet is indicated in case of chronic HBV infection. Entaliv 0.5mg Tablet is co-administered safely with other antiretrovirals for HIV. Entaliv 0.5mg Tablet is indicated in ages above 2 years of age.

Entaliv 0.5mg Tablet contains its active substance called Entecavir. Entecavir is guanosine nucleoside analogue. Entecavir acts against HBV polymerase. It competes with deoxyguanosine triphosphate and entecavir triphosphate inhibits all functions of HBV polymerase which is required for replication of virus. Thus, treats HBV infection.

Entaliv 0.5mg Tablet is HIV-1 guanosine nucleoside analogue. Entaliv 0.5mg Tablet inhibits the action of HBV polymerase by incorporating themselves into the nucleotide sequence thus inhibits the action of HBV polymerase, thereby preventing the formation of mature virus particles. Thus, controls and treats HBV infection.

Absolute contraindications:

• if you are allergic to Entaliv 0.5mg Tablet.
• if you have renal diseases
• if you are pregnant
• if you are diabetic
• if you have liver metabolism disorders

Common side effects that occur 1:100 patients: headache, insomnia, fatigue, dizziness, somnolence, vomiting, diarrhoea, nausea, dyspepsia, and increased blood levels of liver enzymes. Decreased levels of neutrophils

Uncommon side effects that occur 1:1000 patients: rash, hair loss, hematuria

Rare side effects that occur 1:10,000 patients: severe allergic reaction, lactic acidosis

• Is Entaliv 0.5mg Tablet safe during pregnancy?

No, taking Entaliv 0.5mg Tablet during pregnancy is not recommended. Consult your physician.

• Can Entaliv 0.5mg Tablet be taken while breast feeding?

No, taking Entaliv 0.5mg Tablet is not recommended during breast feeding. Consult your physician.

• Can Entaliv 0.5mg Tablet be taken while alcohol consumption?

The interaction is unknown but this medication causes side effects. Thus, consult your physician.

• Can I take drive or operate heavy machineries while on Entaliv 0.5mg Tablet?

This medication causes side effects thus caution is used while driving or operating machineries.

• Can Entaliv 0.5mg Tablet be taken as a treatment for HIV?

No, Entaliv 0.5mg Tablet is not an antiretroviral but it can be used with other antiretrovirals that treat HIV infection

Alcohol

Entaliv 0.5mg Tablet generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

Driving or operating machinery

It is preferred to drive or operate heavy machinery with caution as Entaliv 0.5mg Tablet causes side effects. For further queries, consult your physician.

Pregnancy

The use of Entaliv 0.5mg Tablet is not recommended during pregnancy.

Breast Feeding

The use of Entaliv 0.5mg Tablet during breastfeeding is not recommended.

Kidney Problem

Renal filtration impairment – monitor function. For further queries, consult your physician.

Liver Disease

• Compensated and decompensated liver disease
• Monitor liver function before and during therapy, especially in patients with other
• Exacerbation of hepatitis after completion of treatment

• Entaliv 0.5mg Tablet is taken orally without food for best result.
• Entaliv 0.5mg Tablet must be taken at the same time once a day as prescribed by your physician.
• Entaliv 0.5mg Tablet is always taken with other antiretrovirals for treating HIV infection.
• After therapy has been initiated, do not take more or less of this drug than prescribed or stop taking it without your physicians’ approval. Skipping or changing your dose without approval may cause the amount of the virus to increase making the infection more difficult to treat, or worsen side effects.

• If you are pregnant or breastfeeding inform your physician as they are not advisable.
• The recommended dosage of Entaliv 0.5mg Tablet in compensated liver disease is 0.5mg/d in naïve cases
• The recommended dosage of Entaliv 0.5mg Tablet in compensated liver disease is 1mg/d in pre-exposed cases
• The recommended dosage of Entaliv 0.5mg Tablet in decompensated liver disease is 1mg/d
• Entaliv can be taken with other antiretrovirals as prescribed by the physician without fail. These drugs must be taken with or without food on a regular time basis.

Entaliv 0.5mg Tablet is used in children above 2 years of age or 10 Kgs of weight in naïve cases

                Upto 30 kgs – 0.5mg/d

                >30 kgs – 1mg/d

Entaliv 0.5mg Tablet used in children above 2 years of age or 10 Kgs of weight in pre-exposed cases, the dosage is doubled.

Entaliv 0.5mg Tablet can be taken with other antiretrovirals as prescribed by the physician without fail. These drugs must be taken with or without food on a regular time basis.

Entaliv 0.5mg Tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.

• If you have any allergy
• If you have a liver problem
• If you have a kidney problem
• If you are diabetic
• If you are pregnant or breastfeeding

Entaliv 0.5mg Tablet is taken orally as prescribed dosage at specific time regularly. It can be safely used in cases of HIV cases who are on a regime

Drug-Drug Interaction

Alendronate/amikacin/amiloride/azilsartan

benazepril

candesartan/captopril/cidofovir/creatine /cyclosporine

diflunisal

enalapril/eprosartan/ethacrynic acid/etidronate

foscarnet/fosinopril

gallium nitrate/ganciclovir/gentamicin

ibandronate/irbesartan

kanamycin

letermovir/lisinopril/losartan

mannitol/mefenamic acid/mesalamine

neomycin

Olmesartan/oxaliplatin

Pamidronate /pentamidine/perindopril/pindolol /polymyxin B/procainamide

quinapril

ramipril/risedronate/

sacubitril/streptomycin/sulindac

tacrolimus/telavancin/telmisartan/tobramycin/trandolapril/triamterene

valganciclovir/valsartan

zoledronic acid/zonisamide

Drug-Food Interaction

Entaliv 0.5mg Tablet can be safely taken with any type of food, if doubts arise kindly refer to your physician. Entaliv 0.5mg Tablet generally causes side effects thus it is advised not to be taken with alcohol. It is preferred to drive or operate heavy machinery with caution.

Contact your doctor, pharmacist or nurse immediately.

• If you take once a day dosage, then the missed dosage if you notice within 12 hours. If it is more than 12 hours, then skip the dosage and take the next doses as usual.
• If you take twice a day dosage, then the missed dosage if you notice within 6 hours. If it is more than 6 hours, then skip the dosage and take the next doses as usual.
• Always take with other antiretrovirals Don’t take a double dose for a forgotten dose.

• Keep the medication out of children’s reach
• Keep the medication away from pets
• Once expired dispose immediately
• Store at 30C

• Entaliv 0.5mg Tablet contains its active substance called entecavir.
• It is a nucleoside guanosine analogue.
• It is used to control and treat HBV infection
• Do not use this medication while lactation period.
• Don’t use this medication with liver disease and kidney diseases.