Brand Name Esiloc 40mg Tablet
Salt Composition Esomeprazole (40mg)
Strength 40mg
Product Form Tablet
Storage Store at room temperature (10-30°C)
Category Gastro Intestional Tract
Country of Origin India
Manufacturer Cadila Pharmaceuticals
Manufacturer/Marketer AddressCadila Pharmaceuticals,,Cadila Corporate Campus, Sarkhej Dholka road, Bhat, India
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M.R.P : Rs.54.80       Price : Rs.46.58

You Save : Rs.8.22    Inclusive of all taxes

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Availability : In Stock


    Medical Description of Esiloc 40mg Tablet

    Esiloc 40mg  Tablet contains Esomeprazole 40mg is used in the treatment of Gastroesophageal reflux disease (GERD) and peptic ulcer disease. It helps to give relief from acid-related indigestion and heartburn. It works by decreasing acid secretion in the parietal cells of the stomach. It should be taken on an empty stomach preferably in the morning. Avoid spicy, fatty and caffeinated drinks such as tea, coffee and soft drinks.


    Esiloc 40mg Tablet Uses

    Used for the treatment of Gastroesophageal reflux disease (GERD) and peptic ulcer disease. It helps to give relief from acid-related indigestion and heartburn. It decreases the acid secretion in the stomach


    Esiloc 40mg Tablet Benefits

    Gastroesophageal reflux disease (GERD)

    GERD occurs due to stomach acid frequently flows backward direction from stomach to the oesophagus. Heartburn and acid indigestion are the symptoms of GERD. Esomeprazole is used to treat the backflow acid secretion in the stomach. Also, need sometimes surgery.

    Peptic ulcer disease

    It is a disease caused by Helicobacter pylori bacteria. It causes gastritis and peptic ulcer disease. H.Pylori bacteria mainly affects the lining of the stomach and has less effect on acid secretion. Esomeprazole with an antibiotic combination is used to treat this condition.

    Zollinger-Ellison syndrome

    It is a condition where tumours form in the pancreas and duodenum. These forming tumours secrete gastrin hormone, which in turn causes more acid secretion in the stomach. Esomeprazole is used to treat acid suppression in the stomach due to tumours.

    Erosive esophagitis

    The swelling of esophagus (the muscular tube that helps food moves from the throat to the stomach) is called Esophagitis. It is caused due to excess acid production back flow from stomach to esophagus, resulting in a condition called Erosive esophagitis; it should irritate, and damages the lining of the esophagus. This medicine is used to treat this acid suppression in the stomach.


    Esiloc 40mg Tablet Indication

    This medicine is prescribed for the treatment of Gastroesophageal reflux disease (GERD) and peptic ulcer disease. It helps to give relief from acid-related indigestion and heartburn. It works by decreasing acid secretion in the parietal cells of the stomach.

    It should be taken one hour before the meal. Better to take on an empty stomach as prescribed by the doctor. It should be swallowed the whole tablet at once. Do not chew, crush and break it.


    Mechanism of action of Esiloc 40mg Tablet

    Esiloc 40mg (Esomeprazole) acts on the final step of gastric acid secretion; it blocks the acid releasing gastric parietal cells of the stomach. The parietal cell of the stomach contains H+/K+ ATP Pumps, which helps in acid secretion and then inhibits acid production by blocking these H+K+ ATP pumps. This action will last up to 24 hours, in between, more pumps will be produced by the stomach, which indicates the need to take the next dose to prevent the acid production in the stomach.


    How Esiloc 40mg Tablet works

    Esomeprazole is a proton pump inhibitor used to treat acid secretion from the parietal cells of the stomach. Mainly proton pump inhibitors act on sodium-potassium pumps located in the inner lining of the stomach, these pumps release acid secretion into the stomach. Esomeprazole blocks the effect of acid secreted cells, which decreases acidity in the stomach. It gives relief from the acidity.


    Esiloc 40mg Tablet Contraindication

    This medicine is contraindicated to allergic symptoms such as skin rashes, itching, swelling, breathing difficulties etc, liver dysfunction, vitamin, and mineral deficiency.


    Esiloc 40mg Tablet Side Effects

    Diarrhoea

    Stomach pain

    Headache

    Nausea

    Vomiting

    Dizziness

    Drowsiness

    Sleepiness


    FAQs for Esiloc 40mg Tablet

    Does Esiloc 40mg (Esomeprazole 40mg) Tablet contain habit-forming drugs?

    No, Esiloc 40mg Tablet doesn’t have habit forming tendency.

    what is the time duration for Esiloc 40mg Tablet to react on the body?

    Esiloc 40mg Tablet shows its action within one hour after administration. It will take 2 to 3 days for better relief and 4 to 5 weeks will take for complete relief.

    How long Esiloc 40mg Tablet will sustain in our body?

    Esiloc 40mg Tablet remains for 24hrs in our body.

    Is it safe during pregnancy?

    No. It is not safe during pregnancy. It shows an effect on the fetus. Ask your doctor, and then take for a better quality of life.

    Can we take over years of time?

    Long-term use of this medicine leads to develop atrophic gastritis, vitamin, and mineral deficiencies. Ask your doctor, and then take for a better quality of life.


    Precautions and general warning of Esiloc 40mg Tablet

    Alcohol

    No results were found, not get proper information. By using alcohol leads to develop acidity, which leads to worsening the patient health conditions. Ask your doctor, and then take for a better quality of life.

    Driving or operating machinery

    No. Esiloc 40mg Tablet is not safe to drive after administration. It causes dizziness, sleepiness, and alters the ability to drive. Ask your doctor, and then take for a better quality of life.

    Pregnancy

    No. This tablet is not safe during pregnancy. It shows the effect on the fetus. Ask your doctor, and then take for a better quality of life.

    Breast Feeding

    No. Esiloc 40mg Tablet is not safe during breastfeeding. It shows the effect on the babies, secreted through breast milk. Ask your doctor, and then take for a better quality of life.

    Kidney Problem

    Yes. It is safe in patients with kidney diseases. It doesn’t show the effect on the kidneys. Ask your doctor, and then take for a better quality of life.

    Liver Disease

    This tablet should be used with caution in patients with hepatic dysfunction; hepatic impairment, or liver diseases. Then it leads to the risk of liver dysfunction or liver damage. Inform your doctor, and then take for a better life. Based on the patient clinical conditions, dose adjustment or replacement is needed.


    How to Take Esiloc 40mg Tablet

    Esiloc 40mg Tablet should be taken on an empty stomach, at least one hour before the meal as prescribed by the doctor. Take this medicine at a fixed time intervals. It is better, try to finish your dinner three hours before going to bed, for reducing the acid secretion in the stomach.

    Take the correct dose and duration of medicine as prescribed by the doctor. Swallow the whole capsule at once. Don’t break, chewed or crushed the capsule.


    Use of Esiloc 40mg Tablet in Adult

    It is considered safe to use this medicine in adults. Kindly consult with your doctor.


    Use of Esiloc 40mg Tablet in children

    No information is available regarding the use of this medicine in children who are below 1 year old. Kindly consult with the doctor.


    Use of Esiloc 40mg Tablet in Elderly Patients

    It is considered safe to use this medicine and dose adjustment is not required in an elderly patient. Kindly consult with your doctor.


    Other general warnings

    If you are allergic to Esomeprazole. Informed the doctor before prescribing this medicine. If you noticed any allergic symptoms such as skin rashes, itching, swelling, breathing difficulties, etc. Immediately meet your doctor, for a better quality of a life.


    Talk to your doctor if

    If you’re allergic to the composition of the medicines

    If you’re using any concomitant medications

    If you’re not responding to the treatment


    General instructions

    Esomeprazole is used for the treatment of Gastroesophageal reflux disease (GERD) and peptic ulcer disease. It helps to give relief from acid-related indigestion and heartburn. It works by decreasing acid secretion in the parietal cells of the stomach.

    It starts its action within one hour after administration. It shows its effect within 2-3 days after administering this drug, then 4-5 weeks taken for total better relief.

    It should be taken one hour before a meal with water. Do not take spicy, fatty foods, alcohol, caffeinated drinks or beverage such as coffee, tea, and cola while taking this medicine. Take an adequate balanced diet. Avoid late-night dinners, it reduces the acidity. Better to take food for 3 hours before going to bed.


    Drug Interaction of Esiloc 40mg Tablet

    Drug-Drug Interaction

    Fluconazole

    Fluconazole is an antifungal drug used to treat fungal infection. This drug need acidic condition to absorb in the intestine. By using this medicine with esomeprazole affects the absorption of drug in intestine.

    Methotrexate

    Methotrexate is an anti-rheumatic drug. Methotrexate with esomeprazole can cause increased methotrexate levels, leads to toxic. Consult the doctor before giving these two-drug combinations at a time. Mostly avoid these combinations, managed by giving time gap between them

    Warfarin

    Warfarin is an anticoagulant. Warfarin with esomeprazole combination can cause increased bleeding. Monitor frequently, consult the doctor immediately if taking both at a time.  If it needs to give, adjust the time gap between them.

    Nelfinavir

    It is an antiretroviral drug. It needs acidic condition to absorb drug in the intestine. In combination with esomeprazole can affects the absorption of drug in the intestine.

    Clopidogrel

    Esomeprazole with clopidogrel leads to decreases the levels of clopidogrel in the blood. It leads to the risk of blood clots. 

    Drug-Food Interaction

    It should be taken one hour before a meal with water. Do not take spicy, fatty foods, alcohol, caffeinated drinks or beverage such as coffee, tea, and cola while taking this medicine. Remember to try to finish your dinner three hours before going to bed. Then only it should prevent acid secretion in the stomach while taking with foods. Avoid acid-containing foods to relieve symptoms easily.

    Drug-Disease Interaction

    Hypomagnesemia

    Esomeprazole long term causes magnesium deficiency (hypomagnesemia). If you’re noticed dizziness, shivering, muscle pin, irregular heartbeat, seizures or fits, immediately consult the doctor. Monitor magnesium levels at regular intervals.

    Lupus erythematosus

    It is an autoimmune disease shows mainly affecting the joints, brain, kidneys, skin and other organs. By using esomeprazole, it can be occurred. If you experienced any of these side effects tiredness, painful joints, rashes or lesions on the skin by using esomeprazole, immediately consult the doctor for better life.

    Bone fractures

    Long-term use of esomeprazole can cause calcium deficiency, leads to show effects on bone. By overcoming this condition, add vitamin D supplements with esomeprazole helps to increase calcium absorption in the body.

    Vitamin and mineral deficenecy

    Long term use of rabeprazole leads to vitamin and mineral deficiency. To overcome this, adequate vitamin and mineral supplements with esomeprazole is needed.


    Over Dose

    Take the doses properly as directed by the doctor. Do not be taken as an overdose. If you are taken, unfortunately, immediately consult the doctor for a better quality of life.


    Missed Dose

    Do not skip the dose of esomeprazole as directed by the doctor. If you skipped the dose, take it immediately. If you skipped the dose, it's nearer to the next dose, take properly one dose, do not be taken as double the dose. It leads to overdose, immediately consult the doctor.


    Storage and Disposal

    Stored at  Below 30C degrees in a tightly closed container.

    Protect from light and heat.

    Keep away from children and pets. Unless it becomes toxic to them.

    Disposed of properly in suitable dustbins.


    Fast Tag

    Esomeprazole is used for the treatment of Gastroesophageal reflux disease (GERD) and peptic ulcer disease. It helps to give relief from acid-related indigestion and heartburn. It works by decreasing acid secretion in the parietal cells of the stomach.

    It should be taken one hour before a meal with water. Do not take spicy, fatty foods, alcohol, caffeinated drinks or beverage such as coffee, tea, and cola while taking this medicine. Remember to try to finish your dinner three hours before going to bed.

    Long term use of this medicine produces bone fractures, vitamin and mineral deficiencies. If necessary, consult the doctor and take.

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