Falcigo Plus injection

Brand Name Falcigo Plus injection
Salt Composition Artesunate (50mg) + Mefloquine (250mg)
Strength 50mg + 250mg
Product Form Injection
Pack 1 Injection in 1 Vial
Storage Store at room temperature (10-30°C)
Category Antimalarial
Country of Origin India
Manufacturer Zydus Cadila
Manufacturer/Marketer AddressZydus Cadila,Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
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M.R.P : Rs.348.01    

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1 Injection in 1 Vial

Availability : In Stock

  Online Payment Only



    Medical Description of Falcigo Plus injection

    Falcigo Plus Injection contains Artesunate 50mg and Mefloquine 250mg used to treat parasitic infections such as Malaria. Mefloquine 250mg is an antimalarial drug that results in interacting with certain substances which are required for the malarial parasitic cells present in our blood for their vital functions. It is usually effective against plasmodium vivax, and Plasmodium ovale strains of malarial parasites and it is also used to treat the infections caused by chloroquine-resistant strains of malarial parasites. Artesunate 50mg is an antimalarial drug, results in interacting with certain substances which are required for the malarial parasite present in the blood to do its vital functions. Then it eradicates the malarial infection caused by Plasmodium falciparum strains of malarial parasite. It is particularly used to treat malaria disease (resistant to other antimalarial medicines). Also, used to treat uncomplicated malaria disease with a combination of other antimalarial medicines. The combination of this medicine produces its action by killing the parasite that causes infection and also helps to prevent the infections.


    Falcigo Plus injection Uses

    It is used in the treatment of the following conditions as parasitic infections such as Malaria


    Falcigo Plus injection Benefits

    Parasitic infections

    It is an organism that lives in another organism like your body for its food and place to survive. You can get a parasitic infection from contaminated water, food, bug bites o sexual contact. It is a one-celled organism called protozoa which can be seen in the naked eye. Symptoms include stomach pain, nausea, vomiting, dehydration, weight loss, inflamed lymph nodes, constipation, diarrhea, rashes, eczema, hives, muscle, and joint pain.

    Malaria

    Falcigo Plus Injection is used to treat malaria disease caused by plasmodium falciparum strains of malarial parasite. Also, used to treat the malaria disease (resistant to other antimalarial medicines) which leads to developing a fever, chills, nausea, vomiting, headache, muscle pain, etc.


    Falcigo Plus injection Indication

    The Falcigo Plus Injection is prescribed in the following indications as Malaria


    Mechanism of action of Falcigo Plus injection

    The Falcigo Plus Injection contains Artesunate 50mg and Mefloquine 250mg it is a combination of two medicines. Artesunate 50mg is an antiparasitic medicine that produces its action by producing the free radicals (harmful substances) within the malarial parasite present in the blood this helps to kill the parasite. Mefloquine 250mg is an antimalarial drug that produces its action by increasing the time (a toxic substance to parasites) in your blood. This kills the parasite that is present in your blood and inhibits the growth of bacteria that cause infections.


    How Falcigo Plus injection works

    The Falcigo Plus Injection contains Artesunate 50mg and Mefloquine 250mg it is a combination of two medicines. Artesunate 50mg is an antiparasitic medicine that produces its action by producing the free radicals (harmful substances) within the malarial parasite present in the blood this helps to kill the parasite. Mefloquine 250mg is an antimalarial drug that produces its action by increasing the time (a toxic substance to parasites) in your blood. This kills the parasite that is present in your blood and inhibits the growth of bacteria that cause infections.


    Falcigo Plus injection Contraindication

    • Do not take this medicine if you are allergic to Artesunate, Mefloquine, Quinine, and Quinidine
    • It is contraindicated to use this medicine if you have psychiatric disorders and seizures
    • Kindly avoid using this medicine if you have taken the antifungal medicine recently
    • It is contraindicated to use this medicine as a prophylaxis in patients who are having a history of depression, generalized anxiety disorder, psychosis, schizophrenia, and convulsions


    Falcigo Plus injection Side Effects

    • Nausea
    • Vomiting
    • Dizziness
    • Sleepiness
    • Abdominal pain
    • Diarrhea
    • Headache
    • Fatigue
    • Palpitation
    • Yellow-colored skin, and eyes


    FAQs for Falcigo Plus injection

    • How long should I take the Falcigo Plus Injection?

    Normally the duration of this medicine depends upon the severity of the disease. You should take this according to your doctor advice

    • Is the Falcigo Plus Injection is safe?

    Yes, it is considered safe when you have taken the medication as per the dose and duration advised by the doctor. If you stop the medicine without completing the course of treatment it may worsen the conditions

    • What if I do not get better after using the Falcigo Plus Injection?

    If you do not feel better after completing the full course of treatment kindly inform your doctor.


    Precautions and general warning of Falcigo Plus injection

    Alcohol

    The use of alcohol may produce harmful effects while you are receiving this treatment. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects on the fetus. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered safe during breastfeeding because it does not excrete via breast milk. Kindly consult with your doctor

    Kidney Problem

    Limited information is available regarding the use of this medicine in patients who are having a renal impairment. Kindly consult with your doctor.

    Liver Disease

    Falcigo Plus Injection should be used with caution in patients with hepatic impairment. The use of this medicine required dose modification. Kindly consult with your doctor.


    How to Take Falcigo Plus injection

    Falcigo Plus Injection comes in an liquid dosage form and shakes well before use. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Falcigo Plus injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.


    Use of Falcigo Plus injection in children

    It is considered unsafe to use this medicine in children who are below 6 months old. Kindly consult with your doctor.


    Use of Falcigo Plus injection in Elderly Patients

    Falcigo Plus Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient


    Other general warnings

    • Therapy should be administered with caution because the use of this medicine may increase the QT interval
    • Long-term use may cause neuropsychiatric effects
    • Therapy should be administered with caution in patients who are having a hepatic impairment
    • The use of this medicine may cause agranulocytosis and aplastic anemia
    • The use of this medicine may cause psychiatric and neurological side effects and it also causes suicidal ideation
    • The use of this medicine may increase the risk of developing epilepsy
    • The use of this medicine may cause hypotension, dyspnea, urticaria, or generalized rash
    • Post-artesunate delayed hemolysis is characterized by a decrease in the level of hemoglobin and leads to cause hemolytic anemia

                Ophthalmic effects

    • It leads to developing ophthalmic abnormalities (vision changes, retina abnormalities, etc.), leading to worsening the patient's health conditions. Regularly monitoring the ophthalmic examination is needed in patients using this medicine.

                 Preventive use

    • If you noticed symptoms of malaria again after administration of this medicine immediately stop taking the medicine, and start treatment with other antimalarial drugs.

                 Drug resistance

    • You may develop resistance to the drug if you withdraw the drug without completing the full course of treatment.

                 Quinine associated blackwater fever

    • It should not be recommended in patients with blackwater fever (a complication of malaria infection) associated quinine drug, leading to worsening the patient's health conditions.


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You are having a concomitant disease or taking any medications


    General instructions

    Falcigo Plus Injection consist of Artesunate 50mg and Mefloquine 250mg is used to treat Malaria diseases (caused by Plasmodium falciparum strains of malarial parasite).

    Artesunate 50mg and Mefloquine 250mg are the antimalarial drug combination together prevents the acute uncomplicated malarial infection effectively. Also, used to treat malaria disease (resistant to other antimalarial medicines), and infections caused by chloroquine-resistant strains of malarial parasites.


    Drug Interaction of Falcigo Plus injection

    Drug-Drug Interaction

    BCG vaccine live

    The use of this drug is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism

    Lefamulin

    The use of this drug is contraindicated because the use of lefamulin will increase the effect of Mefloquine by affecting its hepatic and intestinal enzyme metabolism.

    Afatinib

    Use alternative drug because the use of mefloquine increases the effect of afatinib by P-glycoprotein efflux transporter

    Apomorphine

    Use alternative drug because the combination of this drug increases the QTc interval

    Tepotinib

    Use alternative drugs because the use of sotorasib will decrease the effect of artesunate by P-glycoprotein efflux transporter.

    Carbamazepine
    Therapy should be administered with caution because the use of carbamazepine will decrease the effect of artesunate by increasing its metabolism.

    Diclofenac

    Therapy should be administered with caution because the use of diclofenac will increase the effect of diclofenac by decreasing its metabolism.

    Dapsone

    Use alternative drug because the use of mefloquine increases the toxicity of the dapsone by unspecified interaction mechanism and it also increases the risk for developing hemolytic reactions

    Drug-Food Interaction

    Food may increase the effect of this medicine on your body. So take the medicine as soon you complete your meal.

    Drug-Disease Interaction

    Hematological toxicity

    Therapy should be used with caution in patients with hematological toxicity (leads to developing anemia, leukemia, thrombocytopenia, etc.), which leads to worsening the patient's health conditions. Based on the patient's health conditions, dose adjustment, or replacement is needed.

    Liver diseases

    Therapy should be used with caution in a patient with hepatic impairment or liver diseases. Then it leads to the risk of liver damage. Based on the patient clinical conditions, dose adjustment or replacement is needed.

    Psychiatric disorders

    Therapy should be used with caution in patients with psychiatric disorders (depression, agitation, anxiety, psychoses), which leads to worsening the patient's health conditions. Based on the patient's health conditions, dose adjustment, or replacement is needed.

    Heart diseases

    Therapy should be used with caution in patients with heart diseases (QT Prolongation, irregular heartbeat, breathing difficulty, arrhythmia, etc.), which leads to worsening the patient's health conditions. Based on the patient's health conditions, dose adjustment, or replacement is needed.

    Cutaneous toxicity

    Therapy should be used with caution in patients with cutaneous toxicity (skin diseases), which leads to worsening the patient's health conditions. Based on the patient's health conditions, dose adjustment, or replacement is needed.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    Falcigo Plus Injection contains Artesunate 50mg and Mefloquine 250mg used to treat parasitic infections such as Malaria. Artesunate 50mg and Mefloquine 250mg are antimalarial drugs, result in interacting with certain substances (required for vital functions of the malarial parasite cell) present in the blood. This drug combination together prevents the malarial infection (caused by Plasmodium falciparum strains of malarial parasite) effectively. Also, used to treat malaria disease (resistant to other antimalarial medicines), and infections caused by chloroquine-resistant strains of malarial parasites.