Fludocyte 50mg Injection

Brand Name Fludocyte 50mg Injection
Salt Composition

Fludarabine (50mg)

Strength 50mg
Product Form Injection
Pack 1 x 2ml in 1 Vial
Category

Anti-Cancer

SubCategory

Blood Cancer

Country of Origin India
Manufacturer

Intas Pharmaceuticals Ltd

Manufacturer/Marketer Address Intas Pharmaceuticals Ltd,Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
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M.R.P : Rs.10277.13       Price : Rs.8221.70

You Save : Rs.2,055.43    Inclusive of all taxes

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1 x 2ml in 1 Vial

Availability : In Stock

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    Medical Description of Fludocyte 50mg Injection

    Fludocyte 50mg Injection contains Fludarabine 50mg used to treat chronic lymphocytic leukemia. It works by inhibiting the growth and multiplication by interfering in the DNA and RNA of cancer cells. It is used alone or with a combination. It is not recommended in children.


    Fludocyte 50mg Injection Uses

    It is used in the treatment of the following conditions chronic lymphocytic leukemia.


    Fludocyte 50mg Injection Benefits

    Chronic lymphatic leukemia

    It is a type of blood and bone marrow cancer. The exact cause is unknown but it is assumed that some changes happen in the DNA of blood-producing cells. It progresses more slowly when compared with other leukemia. Symptoms include inflamed lymph nodes, fever, night sweats, weight loss, enlarged spleen, fatigue, and frequent infections.


    Fludocyte 50mg Injection Indication

    The Fludocyte 50mg Injection is prescribed in the following indications as chronic lymphocytic leukemia

     


    Mechanism of action of Fludocyte 50mg Injection

    Fludocyte 50mg Injection contains Fludarabine 50mg is an anti-cancer medication, an antimetabolite. It is a fluorinated nucleotide that is actively dephosphorylated to 2-fluoro-ara-A and it is further phosphorylated by deoxycytidine kinas to 2-fluoro-ara-ATP which produces its action by inhibiting the DNA polymerase alpha, ribonucleotide reductase, and DNA primase which results in inhibition of DNA synthesis and leads to cell death.


    How Fludocyte 50mg Injection works

    Fludocyte 50mg Injection contains Fludarabine 50mg is an anti-cancer medication, an antimetabolite. It produces its action by interfering with the growth of DNA and RNA of cancer cells and preventing the growth and multiplication of abnormal cells

     


    Fludocyte 50mg Injection Contraindication

    • Do not take this medicine if you are allergic to Fludarabine
    • Do not use this medicine along with pentostatin because the combination of this medicine increases the risk of pulmonary toxicity


    Fludocyte 50mg Injection Side Effects

    • Fever
    • Thrombocytopenia
    • Infection
    • Injection site pain
    • Cough
    • Pain
    • Pneumonia
    • Edema
    • Rash
    • Diarrhea
    • Visual disturbances
    • GI bleeding
    • Abdominal pain
    • Hearing loss
    • Hair loss

     


    FAQs for Fludocyte 50mg Injection

    • When can I plan a pregnancy if I am taking a Fludocyte 50mg Injection?

    Avoid planning for pregnancy while you are receiving this medicine and also use an effective contraceptive for at least 1 month after taking the last medicine.

    • When should I call my doctor right away?

    If you have experienced muscle cramping, muscle weakness, confusion, vision loss, blindness, seizures, headaches, shortness of breath, swelling of your feet, high blood pressure, tiredness, fainting, tightness in the chest.

    • I am experiencing nausea and fatigue. Is this due to the Fludocyte 50mg Injection?

    Yes, the common side effect of this medicine is nausea and fatigue so it is better to eat more frequent meals to decrease nausea and also avoid foods that are salty, spicy, fatty. Drink plenty of rest and do light exercise to keep yourself active


    Precautions and general warning of Fludocyte 50mg Injection

    Alcohol

    It is not clear that consuming alcohol is safe while you are receiving this medicine. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor

    Kidney Problem

    The medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    The medicine should be used with caution in patients with hepatic impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

     


    How to Take Fludocyte 50mg Injection

    Fludocyte 50mg Injection comes in a liquid solution as an intravenous. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Fludocyte 50mg Injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor


    Use of Fludocyte 50mg Injection in children

    Safety and efficacy were not established in children who are below 18 years old. Kindly consult with your doctor.


    Use of Fludocyte 50mg Injection in Elderly Patients

    Fludocyte 50mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • In elderly patients, bone marrow depression and renal impairment may occur
    • The use of this medicine increases the risk of developing autoimmune hemolytic anemia
    • Kindly avoid pregnancy while you are receiving this medicine it may cause fetal harm


    Talk to your doctor if

    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have a receiving any concomitant medication and disease
    • You develop shortness of breath


    General instructions

    Fludarabine 50mg is used to treat chronic lymphocytic leukemia. It produces its action by interfering with the growth of DNA and RNA of cancer cells and preventing the growth and multiplication of abnormal cells.


    Drug Interaction of Fludocyte 50mg Injection

    Drug-Drug Interaction

    Tofacitinib

    Use alternative drug because the combination of this medicine either increases the toxicity of the other by immunosuppressive effects and it also increases the risk for developing an infection

    Dichlorphenamide

    Therapy should be administered with caution because the combination of this medicine either increases the toxicity of the other by pharmacodynamic synergism.

    Hydroxyurea

    Therapy should be administered with caution because the combination of this medicine increases the risk of myelosuppression

    Drug-Food Interaction

    No data is available. Kindly consult with your doctor

    Drug-Disease Interaction

    Infections

    The use of this medicine is contraindicated in patients who are having the infectious disease because of their cytotoxic effect their induce myelosuppression.

    Myelosuppression

    Therapy should be administered with caution in patients with bone marrow suppression because the use of this medicine induces dose-related myelosuppression, leucopenia, thrombocytopenia, and anemia

    Hemolytic anemia

    Therapy should be administered with caution in patients with anemia and a history of the hemolytic syndrome because the use of this medicine itself may cause autoimmune hemolytic anemia.

    Renal dysfunction

    The use of this medicine is not recommended in patients who are with severe renal impairment. The patients with moderate renal dysfunction reduce the dose by 20% and monitor closely.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).

     


    Storage and Disposal

    • Stored at 2-8°C in a room temperature.
    • Do not freeze
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • Fludarabine 50mg is an anti-cancer medication, antimetabolite
    • It is used to treat chronic lymphocytic leukemia.
    • Do not withdraw the medicine without consulting with a doctor
    • Use non-hormonal methods of contraception to avoid pregnancy because the use of this medicine may cause fetal harm
    • Kindly consult with your doctor if you have experienced shortness of breath, chest pain, loss of appetite, and dark urine while you are receiving this medicine