Forstavir-EM Tablet

Brand Name Forstavir-EM Tablet
Salt Composition Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)
Strength 300mg + 200mg
Product Form Tablet
Storage Store at room temperature (10-30°C)
Category HIV
Country of Origin India
Manufacturer Aurobindo Pharma Limited
Manufacturer/Marketer AddressAurobindo Pharma Limited,Plot No:# 2, Maitrivihar, Ameerpet Hyderabad - 500 038, Andhra Pradesh, India
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Forstavir-EM Tablet, Emtricitabine 200mg, Tenofovir Disoproxil fumarate 300mg, price, Uses, Side Effects - Drugcarts watermark
M.R.P : Rs.1813.19       Price : Rs.1541.21

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    Medical Description of Forstavir-EM Tablet

    Forstavir-EM tablet contains Tenofovir disoproxil fumarate 300mg and Emtricitabine 200mg. Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is an antiviral medicine used in the treatment of Human Immunodeficiency Virus (HIV)-1 infection. Forstavir-EM tablet is a nucleotide reverse transcriptase inhibitor. Forstavir-EM tablet acts on HIV reverse transcriptase enzyme thus interfere with their reproduction cycle.


    Forstavir-EM Tablet Uses

    Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is used to treat adults and adolescence above 18 years of age who are infected by HIV. Forstavir-EM tablet is used in caution with liver and renal impairment patients.


    Forstavir-EM Tablet Benefits

    Forstavir-EM (Tenofovir disoproxil fumarate 300 mg + Emtricitabine 200 mg) is used with other anti-HIV medication to help control HIV infection. Forstavir-EM tablet helps to decrease the amount of HIV virus in your body thus your immunity works better by reducing your chance of getting HIV complications like co-infections and other cancers. Forstavir-EM tablet is not a cure for HIV infection, it improves immunity that results in longevity of life; thus, precautions are necessary while sexual intercourse, surgery etc. Forstavir-EM tablet is safely used in adolescence above 35 kgs of weight. Forstavir-EM tablet is used as a pre prophylactic to exposure in a previously negative HIV test.


    Forstavir-EM Tablet Indication

    Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is indicated in the treatment of HIV infection that causes AIDS in humans. Forstavir-EM tablet is used with other antiviral medications to boost immunity of the affected hosts by reducing the viral load of the infected cells. Forstavir-EM tablet is safely used in adolescence above 35 kgs of weight. Forstavir-EM tablet is used as a pre prophylactic to exposure in a previously negative HIV test.


    Mechanism of action of Forstavir-EM Tablet

    Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is a nucleotide reverse transcriptase inhibitor. Tenofovir disoproxil fumarate present in Forstavir-EM tablet is an analogue of adenosine 5-monophosphate which is converted to tenofovir after hydrolysis after which tenofovir inhibits HIV-1 reverse transcriptase and HBV reverse transcriptase. Tenofovir competes with AMP as a substrate and competes to incorporate themselves into the DNA strand thus stops the replication of viral particles. Emtricitabine present in Forstavir-EM tablet is an analogue of cytidine is phosphorylated to its active form. Emtricitabine 5 triphosphate inhibits the activity of HIV-1 reverse transcriptase and incorporates themselves into the DNA thus results in the termination of replication process. Thus, the active HIV molecule becomes inactive and further reproduction and multiplication process is stopped by the use of Forstavir-EM tablet.


    How Forstavir-EM Tablet works

    Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet competes with AMP and cytidine respectively and incorporates themselves into DNA strand and thus replication process of viral particle is terminated. Thus, the active HIV molecule becomes inactive and further reproduction and multiplication process is stopped.


    Forstavir-EM Tablet Contraindication

    • if you are a positive HIV case
    • if you are allergic to Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet and its combinate
    • if you have liver disease like hepatitis B or C or hepatomegaly with steatosis
    • if you have kidney impairment
    • if <35 kgs of weight
    • if you are breastfeeding


    Forstavir-EM Tablet Side Effects

    Common side effects that occur 1:10 patients: diarrhea, nausea, fatigue, headache, dizziness, depression, insomnia, abnormal dreams, and rash

    Rare side effects that occur 1:1,000 patients: hepatomegaly, worsening hepatitis B infection, decreased bone density,

    Very rare side effects that occur 1:10,000 patients: lactic acidosis, immune reconstitution syndrome, Interstitial Nephritis, peripheral neuropathy, Fanconi syndrome, renal tubular necrosis, inflammatory hepatitis, angioedema


    FAQs for Forstavir-EM Tablet

    Is Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet safe during pregnancy?

    This medication is not recommended in pregnancy unless pros outweigh the cons. Consult your physician.

    Can Forstavir-EM tablet be taken while breastfeeding?

    There is no specific study to detail this. But in general HIV virions can pass via breastfeeding thus it is suspected that antivirals can also pass via breastfeeding. Thus, consult your physician.

    Can Forstavir-EM tablet be taken while alcohol consumption?

    The interaction is unknown but this medication causes dizziness. Thus, consult your physician.

    Can I take drive or operate heavy machineries while on Forstavir-EM tablet?

    This medication causes dizziness and instability thus caution is used while driving or operating machineries.

    Can Forstavir-EM tablet be taken as a prophylactic?

    Yes, only if you are tested negative immediately after exposure. Please consult a physician before use.


    Precautions and general warning of Forstavir-EM Tablet

    Alcohol

    Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

    Driving or operating machinery

    It is preferred to drive or operate heavy machinery with caution as Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet causes side effects. For further queries, consult your physician.

    Pregnancy

    Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is cautiously used during pregnancy as it may cause some side effects on the fetus. Thus, consult your physician.

    Breast Feeding

    The use of Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet during breastfeeding is not recommended as evidence shows less amount of the medication passes via breastfeeding to the baby that may cause adverse effect in newborn.

    Kidney Problem

    Inform your physician if you have compromised kidney function as Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet may cause renal disorders that results in end-stage kidney failure

    Liver Disease

    Inform your physician if you have hepatitis B or C

    Hepatomegaly with steatosis


    How to Take Forstavir-EM Tablet

    Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is taken orally with or without food.

    Forstavir-EM tablet should be taken at a specific time every day.

    Don’t chew or break the tablet.

    Swallow Forstavir-EM tablet as a whole.

    After therapy has been initiated, do not take more or less of this drug than prescribed or stop taking it without your physicians’ approval. Skipping or changing your dose without approval would increase the viral load making the infection more difficult to treat, or worsen side effects. For further queries consult your physician.


    Use of Forstavir-EM Tablet in Adult

    The recommended dosage is a single dose of Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet taken once per day with or without food


    Use of Forstavir-EM Tablet in children

    The recommended dosage of Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet in single dose taken once per day orally with or without food


    Use of Forstavir-EM Tablet in Elderly Patients

    Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.


    Other general warnings

    • Bone density loss
    • Pancreatitis
    • Lactic acidosis
    • Hepatic decompensation
    • Musculoskeletal problems - Osteonecrosis that causes joint stiffness and pain in larger joints like shoulder, hip, and knee
    • Accumulation or Redistribution of body fat
    • immune reconstitution syndrome.


    Talk to your doctor if

    If you have any allergy

    If you have a liver problem

    If you have any kidney diseases

    If you are pregnant or breastfeeding


    General instructions

    Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is taken at specific time regularly with food. If Forstavir-EM tablet is taken without food the efficiency of medicine is reduced significantly, thus it is ill advised.


    Drug Interaction of Forstavir-EM Tablet

    Drug-Drug Interaction

    Atazanavir/Acyclovir/Amikacin/Amphotericin B

    Carbamazepine/Clarithromycin

    Didanosine/Deferoxime/

    Probenecid/Phenobarbital/Phenytoin

    Ibuprofen

    Ketorolac/Ketoconazole

    Mefenamic acid/ Methadone

    Naproxen

    Fluconazole

    Rifampin

    Drug-Food Interaction

    Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet can be safely taken with any type of food, if doubts arise kindly refer to your physician. Forstavir-EM tablet generally causes known side-effects thus it is advised not to be taken with alcohol.


    Over Dose

    Symptoms of overdose include dizziness, palpitations etc. Contact your doctor immediately.


    Missed Dose

    You can take the missed dosage if you notice within 12 hours if you take them once a day. If it is more than 12 hours, then skip the dosage and take the next doses as usual. Don’t take a double dose for a forgotten dose.


    Storage and Disposal

    Store them at <30°C

    Keep the medication out of children’s reach

    Keep the medication away from pets

    Once expired dispose immediately


    Fast Tag

    Forstavir-EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is a nucleotide reverse transcriptase inhibitor

    It is used to control and treat HIV infection

    Do not use this medication while pregnant and lactation period.

    Don’t use this medication with liver disease and kidney disease.

    Do not use this medication as a prophylactic, consult a physician before use

    This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury etc.