Gcef S 500mg/250mg Injection

Brand Name Gcef S 500mg/250mg Injection
Salt Composition Ceftriaxone (500mg) + Sulbactam (250mg)
Strength 500mg + 250mg
Product Form Injection
Pack 1 Injection in 1 Vial
Storage Store at room temperature (10-30°C)
Category Antibiotic
Country of Origin India
Manufacturer Greenray Pharmaceuticals
Manufacturer/Marketer AddressGreenray Pharmaceuticals Greenray House,Devti Pandru Ghanta,Jalesuar 756032.
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M.R.P : Rs.70.00    

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1 Injection in 1 Vial

Availability : In Stock

  Online Payment Only



    Medical Description of Gcef S 500mg/250mg Injection

    Gcef S 500mg/250mg Injection contains Ceftriaxone 500mg and Salbactum 250mg used to treat conditions like Bacterial infections such as Urinary tract infection, Bronchitis, Community-Acquired Pneumonia, Otitis media, Gonorrhoea, Skin, and soft tissue infection, bone and joint infection, Bacterial meningitis, Bacterial septicemia, Pelvic inflammatory disease, Intra-abdominal infections, Bacteremia, Bacterial endocarditis, Lyme disease. Ceftriaxone is an antibiotic used to treat infections. Mainly bacterial infection targets the ear, eyes, nose, throat, lungs, skin, gastrointestinal tract, and urinary tract. Sulbactam is a β lactamase inhibitor. It should be given with antibiotic, which works by inhibiting the β lactamase enzyme(destroys the action of antibiotics) produced by bacteria. The combination of this medicine helps to fight against microbes and also prevents the growth of bacteria. This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial infections.


    Gcef S 500mg/250mg Injection Uses

    It is used in the treatment of the following conditions as Bacterial infections such as Urinary tract infection, Bronchitis, Community-Acquired Pneumonia, Otitis media, Gonorrhoea, Skin, and soft tissue infection, bone and joint infection, Bacterial meningitis, Bacterial septicemia, Pelvic inflammatory disease, Intra-abdominal infections, Bacteremia, Bacterial endocarditis, Lyme disease.


    Gcef S 500mg/250mg Injection Benefits

    Bacterial infections

    Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

    Pneumonia

    It is a lung infection that causes inflammation in the alveoli. It is usually caused by Streptococcus pneumonia. Symptoms include chest pain, fatigue, fever, sweating, nausea, vomiting, diarrhea, breathing difficulty, cough, and confusion

    Bacterial meningitis

    Infection and inflammation to the meninges (in the brain). It is caused by Streptococcus pneumonia, Neisseria meningtidis, Haemophilus influenza. Symptoms include high fever, stiff neck, severe headache, confusion, and sensitivity to light.

    Intra-abdominal infections

    It is an accumulation of fluid surrounded by inflamed tissue which is present inside your bellies such as peritonitis, pancreatitis, diverticulitis, cholecystitis, and cholangitis. It is caused by Enterobacteriaceae, Enterococci, and Bacteroides fragilis. Symptoms include lack of appetite, belly pain, fever, change in bowel movements, and rectal tenderness.

    Bacteremia

    The presence of bacteria in your bloodstream. It is caused by Staphylococcus aureus, E.coli, Pneumococcal bacteria, Salmonella, and Pseudomonas aeruginosa. Symptoms include fever, chills, and shivering.

    Bacterial endocarditis

    Infection in the inner lining of the heart. It usually occurs when the bacteria enter your bloodstream by destroying your immune system. Symptoms include muscle pain, fatigue, fever, chills, night sweats, shortness of breath, heart murmur, and swelling.

    Lyme disease

    It is also called Borrelia burgdorferi. It usually gets from the bite of an infected tick. Symptoms include red rash, fever, headache, fatigue, muscle pain, and inflamed lymph nodes.

    Bacterial septicemia

    Infection of the blood caused by bacteria leads to increased toxins in the bloodstream passes to the entire body develops organ damage. It occurs due to urinary tract infections, lung infections, kidney infections, and infection in the abdominal area. Symptoms include irregular heartbeat, fever, chills, breathing fast, reduces urine volume, red dots, and shock.

    Pelvic inflammatory disease

    Infection of the female reproductive organs. It usually occurs when sexually transmitted diseases like chlamydia trachomatis, Neisseria gonorrhea spread from your vagina to uterus, fallopian tubes. Symptoms include pain, abnormal vaginal discharge, uterine bleeding, pain during intercourse, and difficulty in urinating.

    Skin infection

    It is usually caused by bacteria, fungi, viruses, and parasites. Common skin infection includes cellulitis, impetigo. Symptoms include red skin, blisters, swelling, pain, red spots, and tenderness


    Gcef S 500mg/250mg Injection Indication

    Gcef S 500mg/250mg Injection is prescribed in the following indications as Urinary tract infection, Bronchitis, Community-Acquired Pneumonia, Otitis media, Gonorrhoea, Skin, and soft tissue infection, bone and joint infection, Bacterial meningitis, Bacterial septicemia, Pelvic inflammatory disease, Intra-abdominal infections, Bacteremia, Bacterial endocarditis, Lyme disease.


    Mechanism of action of Gcef S 500mg/250mg Injection

    Gcef S 500mg/250mg Injection contains Ceftriaxone 500mg and Salbactum 250mg is a third-generation cephalosporin antibiotic that produces its action by preventing bacterial cell wall formation. It helps in preventing the growth and multiplication of microorganisms by killing them Sulbactam is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of Ceftriaxone. The combination with Subactum helps to reduce the development of resistance and increase the action of Ceftriaxone against bacteria.


    How Gcef S 500mg/250mg Injection works

    Gcef S 500mg/250mg Injection contains Ceftriaxone 500mg and Salbactum 250mg is a third-generation cephalosporin antibiotic that produces its action by preventing bacterial cell wall formation. It helps in preventing the growth and multiplication of microorganisms by killing them Sulbactam is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of Ceftriaxone. The combination with Subactum helps to reduce the development of resistance and increase the action of Ceftriaxone against bacteria.


    Gcef S 500mg/250mg Injection Contraindication

    • Do not take this medicine if you are allergic to penicillins, cephalosporins, and Carbapenems
    • The use of this medicine increases the risk of developing bacterial or fungal superinfections
    • It is contraindicated to use this medicine if you are having a previous history of cholestatic jaundice, hepatic dysfunction
    • The use of this medicine may cause toxic epidermal necrolysis, Stevens-Johson syndrome, dermatitis exfoliative.


    Gcef S 500mg/250mg Injection Side Effects

    • Diarrhea
    • Rash
    • Abnormal liver function tests
    • Decreased blood cells (red cells, white cells, and platelets)
    • Fever
    • Chest pain
    • Black or tarry stools
    • Difficulty or painful urination
    • Sore throat
    • Abdominal pain
    • Dizziness
    • Acid or sour taste
    • Swelling Excessive air or gas in the stomach
    • Pain, swelling, and redness at the injection site


    FAQs for Gcef S 500mg/250mg Injection

    • How long does the Gcef S 500mg/250mg Injection take to work?

    Usually, it starts to work as soon as you consume the medicine. But, it may take some days to kill the microbes which are responsible for infection and make you feel better.

    • What if I don’t get better after using the Gcef S 500mg/250mg Injection?

    If you don’t feel better after you finish the full course of treatment. Kindly inform your doctor before your symptoms get worsen.

    • Can I stop taking the Gcef S 500mg/250mg Injection when I feel better?

    No, without completing the full course of treatment you should not withdraw your treatment even if you feel better. Because your symptoms may get worsen


    Precautions and general warning of Gcef S 500mg/250mg Injection

    Alcohol

    The use of alcohol does not produce harmful effects while you are receiving this treatment. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered safe during pregnancy because it does not produce a harmful effect on the developing fetus. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine should be administered with caution during breastfeeding. Kindly stop feeding your child while you are receiving this treatment until the drug is eliminated from the body.

    Kidney Problem

    The medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    The use of this medicine is considered safe in patients with hepatic diseases and it does not require dose modification. Kindly consult with your doctor.


    How to Take Gcef S 500mg/250mg Injection

    Gcef S 500mg/250mg Injection comes in a liquid solution as an intramuscular, intravenous injection. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Gcef S 500mg/250mg Injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.


    Use of Gcef S 500mg/250mg Injection in children

    Gcef S 500mg/250mg Injection is not prescribed in children who are below 28 days. Kindly consult with your doctor.


    Use of Gcef S 500mg/250mg Injection in Elderly Patients

    Gcef S 500mg/250mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • Therapy should be administered with caution if you have a history of penicillin allergy and gastrointestinal disease
    • Long-term use may cause bacterial or fungal overgrowth
    • The use of this medicine may cause Immune-mediated hemolytic anemia, kindly discontinue the treatment if you have anemia
    • The use of this medicine may increase the INR rate in patients with hepatic or renal dysfunctions
    • Therapy should be administered with caution in patients with the gallbladder, biliary tract, liver, or pancreatic disease


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You are suffering from anemia
    • You have watery diarrhea, stomach pain, and fever

     


    General instructions

    Gcef S 500mg/250mg Injection contains Ceftriaxone 1000mg and Salbactum 250mg used to treat conditions like Bacterial infections such as Urinary tract infection, Bronchitis, Community-Acquired Pneumonia, Otitis media, Gonorrhoea, Skin, and soft tissue infection, bone and joint infection, Bacterial meningitis, Bacterial septicemia, Pelvic inflammatory disease, Intra-abdominal infections, Bacteremia, Bacterial endocarditis, Lyme disease. Ceftriaxone 500mg is an antibiotic used to treat infections. Mainly bacterial infection targets the ear, eyes, nose, throat, lungs, skin, gastrointestinal tract, and urinary tract. Sulbactam 250mg is a β lactamase inhibitor. It should be given with antibiotic, which works by inhibiting the β lactamase enzyme(destroys the action of antibiotics) produced by bacteria.


    Drug Interaction of Gcef S 500mg/250mg Injection

    Drug-Drug Interaction

    BCG vaccine live

    The use of this drug is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism

    Cholera vaccine

    Use alternative drugs, because the use of the cholera vaccine with antibiotics may activate the vaccine strain. So, avoid receiving this combination of medicines before 14 days of vaccination

    Dalteparin

    Use alternative medicine because the use of ceftriaxone increases the effect of dalteparin by anticoagulation and it also increases the activity of prothrombin


    Chloramphenicol

    Therapy should be administered with caution because the use of chloramphenicol decreases the effect of ceftriaxone by pharmacodynamic antagonism

    Furosemide

    The use of Ceftriaxone increases the toxicity of furosemide by pharmacodynamic synergism and it also increases the risk of nephrotoxicity

    Probenecid

    It is primarily used to treat gout and hyperuricemia, it increases uric acid excretion in the urine. This injection alters the action of probenecid.

    Drug-Food Interaction

    It is not clear that food may interact with medicine. Kindly consult with your doctor

    Drug-Disease Interaction

    Colitis

    This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This drug should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient’s health condition.

    Seizures

    Using this medicine is needs caution in patients with seizures. It causes hallucinations, anxiety, confusion, and restlessness, etc. Inform the doctor, they will do dose adjustment or replacement if needed. If necessary to take this medicine with seizure medications.

    Hyperbilirubinemia

    The neonates and premature neonates who are having hyperbilirubinemia should not be treated with ceftriaxone injection because bilirubin binds with serum albumin and leads to an increase in the risk for developing bilirubin encephalopathy.

    Gall bladder disease

    Therapy should be administered with caution in patients with gallbladder disease, biliary tract diseases. Because the use of Ceftriaxone get precipitated in the gallbladder and cause abnormalities in sonographic and worsen the symptoms of gallbladder diseases

    Renal impairment

    It should be used with caution in patients with known kidney diseases. Dose adjustment or replacement is needed in some cases based on the patient's clinical condition.

    Hepatic impairment

    It should be used with caution in patients with severe liver diseases. Mild to moderate liver diseases, no need for dose adjustment. In severe conditions, needs dose adjustment.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    Gcef S 500mg/250mg Injection contains Ceftriaxone 500mg and Salbactum 250mg used to treat conditions like Bacterial infections such as Urinary tract infection, Bronchitis, Community-Acquired Pneumonia, Otitis media, Gonorrhoea, Skin, and soft tissue infection, bone and joint infection, Bacterial meningitis, Bacterial septicemia, Pelvic inflammatory disease, Intra-abdominal infections, Bacteremia, Bacterial endocarditis, Lyme disease.

    Ceftriaxone 500mg is a third-generation cephalosporin antibiotic used to treat bacterial infections caused by bacteria. Sulbactam 250mg is a β lactamase inhibitor. It should be given with antibiotic, to inhibit the β lactamase enzyme produced by bacteria. This enzyme destroys the action of antibiotics. Mainly infection affects the brain, ears, lungs, skin, soft tissues, bone and joints, abdomen, and urinary tract.

    It does not depend upon the food timings. It should not be taken orally. Administered by parenterally. It needs clinical or hospital settings to administer the injection. It should be injected by qualified medical practitioners. It will start its action immediately after administration via intravenous or intramuscularly of this medicine.

    It should not be recommended in neonates (patients less than 28 days).