Heptavir 100mg Tablet

Brand Name Heptavir 100mg Tablet
Salt Composition Lamivudine (100mg)
Strength 100mg
Product Form Tablet
Storage Store at room temperature (10-30°C)
Category Hepatitis
Country of Origin India
Manufacturer Hetero Drugs Limited
Manufacturer/Marketer AddressHetero Drugs Limited,Hetero House, H. No. 8-3-166/7/1, Erragadda, Hyderabad, Andhra Pradesh, 500018 India
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M.R.P : Rs.80.00       Price : Rs.60.00

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    Medical Description of Heptavir 100mg Tablet

    Heptavir Tablet contains Lamivudine 100mg. Heptavir (Lamivudine (100mg)) tablet is an antiviral medicine used in the treatment of Human Immunodeficiency Virus (HIV) – 1 infection. It is a nucleoside reverse transcriptase inhibitor.Heptavir tablet improves your immune system and reduces the risk of conditions associated with HIV infection. Heptavir tablet is used in combination with other antivirals for efficiency. It is not used in cases of HBV.


    Heptavir 100mg Tablet Uses

    Heptavir (Lamivudine (100mg)) tablet is used to treat adults and children above 14kgs weight who are infected by HIV-1. It must be taken in combination with other anti-HIV medicines. Your doctor will discuss which combination of medicines is best for you.


    Heptavir 100mg Tablet Benefits

    Heptavir 100mg Tablet used in the treatment for the following condition like 

    Chronic hepatitis B virus infection:

    It is a chronic liver infection that is caused by the hepatitis B virus. It usually occurs when our body cannot fight against the virus and it is a communicable disease. It is caused by sexual contact with an infected person, sharing needles, and it also spread from mother to child during pregnancy and breastfeeding.


    Heptavir 100mg Tablet Indication

    Heptavir (Lamivudine (100mg)) tablet is indicated in the treatment of HIV-1 infection that causes AIDS in humans. Heptavir tablet is used with other antiviral medications to boost the immunity of the affected hosts. It is indicated in ages above 14Kgs of body weight.


    Mechanism of action of Heptavir 100mg Tablet

    Heptavir (Lamivudine (100mg)) tablet is HIV-1 nucleoside reverse transcriptase inhibitor. Lamivudine is phosphorylated to its active forms Heptavir tablet triphosphate that incorporated into the nucleotide and inhibits the action of HIV-1 reverse transcriptase. Thus, the active HIV molecule becomes inactive and further reproduction and multiplication process is stopped.


    How Heptavir 100mg Tablet works

    Heptavir (Lamivudine (100mg)) tablet inhibits the action of HIV-1 reverse transcriptase enzyme by incorporating themselves into the nucleotide sequence thus inhibits the action of the reverse transcriptase of HIV-1, thereby preventing the formation of mature virus particles into infectious virions that spreads the infection and improves immunity.


    Heptavir 100mg Tablet Contraindication

    Absolute contraindications:

    • if you are allergic to Heptavir (Lamivudine (100mg)) tablet
    • if you have a liver disorder like hepatitis B or C or Child-Pugh disease
    • if you have pancreatitis
    • if you have renal diseases

    Relative contraindication:

    • if you are pregnant
    • if you are diabetic


    Heptavir 100mg Tablet Side Effects

    Common side effects that occur 1:10 patients: Headache, insomnia, Cough, nausea, vomiting, abdominal pain or cramps, diarrhea, Rash, alopecia, Arthralgia, Fatigue, malaise, fever.

    Uncommon side effects that occur 1:100 patients: Neutropenia and anemia, thrombocytopenia, raise in AST, ALT levels

    Rare side effects that occur 1:1000 patients: Pure red cell aplasia, Lactic acidosis, Pancreatitis, elevations in serum amylase, Hepatitis, Angioedema, Rhabdomyolysis

    Very rare side effects that occur 1:10,000 patients: Peripheral neuropathy


    FAQs for Heptavir 100mg Tablet

    Is Heptavir (Lamivudine (100mg)) tablet safe during pregnancy?

    Yes, taking Heptavir tablet during pregnancy has decreased the transmission of HIV from mother to fetus. Consult your physician.

    Can Heptavir tablet be taken while breastfeeding?

    No, in general HIV virions can pass via breastfeeding thus it is suspected that antivirals can also pass via breastfeeding.

    Can Heptavir tablet be taken while alcohol consumption?

    The interaction is unknown but this medication causes side effects. Thus, consult your physician.

    Can I take a drive or operate heavy machineries while on Heptavir tablet?

    This medication causes side effects thus caution is used while driving or operating machineries.

    Can Heptavir tablet be taken as monotherapy in HIV treatment?

    No, Heptavir tablet must be taken with other antivirals.


    Precautions and general warning of Heptavir 100mg Tablet

    Alcohol

    Heptavir (Lamivudine (100mg)) tablet generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

    Driving or operating machinery

    It is preferred to drive or operate heavy machinery with caution as Heptavir (Lamivudine (100mg)) tablet causes side effects. For further queries, consult your physician.

    Pregnancy

    The use of Heptavir (Lamivudine (100mg)) tablet is recommended during pregnancy.

    Breast Feeding

    The use of Heptavir (Lamivudine (100mg)) tablet during breastfeeding is not recommended as evidence shows less amount of the medication passes via breastfeeding to the baby that may cause adverse effect in newborn.

    Kidney Problem

    Renal filtration impairment – monitor function. For further queries, consult your physician.

    Liver Disease

    liver disorders and diseases like hepatitis B or C, Child Pugh disease

    Monitor liver function before and during therapy, especially in patients with other


    Use of Heptavir 100mg Tablet in children

    Heptavir (Lamivudine (100mg)) tablet must be taken with other antivirals as prescribed by the physician without fail. These medicines must be taken with or without food on a regular time basis.


    Use of Heptavir 100mg Tablet in Elderly Patients

    Heptavir (Lamivudine (100mg)) tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.


    Other general warnings

    • Skin reactions - It can be mild to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.
    • Musculoskeletal problems - Osteonecrosis that causes joint stiffness and pain in larger joints like shoulder, hip, and knee
    • New onset diabetes mellitus or hyperglycemia – Monitor blood glucose and insulin levels. When needed add oral hypoglycemic and insulin
    • Accumulation or Redistribution of body fat or
    • immune reconstitution syndrome.
    • Any sign of infection – fever or lymph node enlargement


    Talk to your doctor if

    If you have any allergy

    If you have a liver problem

    If you have a kidney problem

    If you are pregnant or breastfeeding


    General instructions

    Heptavir (Lamivudine (100mg)) tablet is taken with other antivirals orally as prescribed dosage at specific time regularly.


    Drug Interaction of Heptavir 100mg Tablet

    Drug-Drug Interaction

    Serum concentration decreased by Acetazolamide, Potassium citrate

    Serum concentration increased by Aceclofenac, Acetaminophen, Alprazolam

    severity of adverse effects is increased by Acyclovir, Amphotericin B, Baclofen

    Drug-Food Interaction

    Heptavir (Lamivudine (100mg)) tablet can be safely taken with any type of food, if doubts arise kindly refer to your physician. Heptavir tablet generally causes side effects thus it is advised not to be taken with alcohol.

    Drug-Disease Interaction

    • Liver disorders – used with caution in severe liver diseases. Consult physician before use
    • Kidney disorders – used with caution in severe kidney diseases. Consult physician before use
    • Cardiac disorders – used with caution in heart failure and MI. Consult physician before use
    • Respiratory disorders – used with caution in respiratory distress. Consult physician before use
    • Pancreases disorders – used with caution in pancreatitis. Consult physician before use


    Over Dose

    Contact your doctor, pharmacist or nurse immediately.


    Missed Dose

    If you take once a day dosage, then the missed dosage if you notice within 12 hours. If it is more than 12 hours, then skip the dosage and take the next doses as usual. If you take twice a day dosage, then the missed dosage if you notice within 6 hours. If it is more than 6 hours, then skip the dosage and take the next doses as usual. Always take with other antivirals Don’t take a double dose for a forgotten dose.


    Storage and Disposal

    Keep the medication out of children’s reach

    Keep the medication away from pets

    Once expired dispose immediately

    Store at 30°C


    Fast Tag

    Heptavir tablet contains Lamivudine 100mg.

    It is a nucleoside reverse transcriptase inhibitor.

    It is used to control and treat HIV infection with other antivirals

    Do not use this medication while the lactation period.

    Don’t use this medication with liver disease and kidney diseases.

    This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury, etc.