Heptavir 10mg Syrup

Heptavir Syrup contains Lamivudine 10mg. Heptavir (Lamivudine (10mg)) syrup is an antiviral medicine used in the treatment of Human Immunodeficiency Virus (HIV) – 1 infection. It is a nucleoside reverse transcriptase inhibitor.Heptavir syrup improves your immune system and reduces the risk of conditions associated with HIV infection. Heptavir syrup is used in combination with other antivirals for efficiency. It is not used in cases of HBV.

Heptavir (Lamivudine (10mg)) syrup is used to treat adults and children above 14kgs weight who are infected by HIV-1. It must be taken in combination with other anti-HIV medicines. Your doctor will discuss which combination of medicines is best for you.

Heptavir 10mg Tablet used in the treatment for the following condition like 

Chronic hepatitis B virus infection:

It is a chronic liver infection that is caused by the hepatitis B virus. It usually occurs when our body cannot fight against the virus and it is a communicable disease. It is caused by sexual contact with an infected person, sharing needles, and it also spread from mother to child during pregnancy and breastfeeding.

Heptavir (Lamivudine (10mg)) syrup is indicated in the treatment of HIV-1 infection that causes AIDS in humans. Heptavir syrup is used with other antiviral medications to boost the immunity of the affected hosts. It is indicated in ages above 14Kgs of body weight.

Heptavir (Lamivudine (10mg)) syrup is HIV-1 nucleoside reverse transcriptase inhibitor. Lamivudine is phosphorylated to its active forms Heptavir syrup triphosphate that incorporated into the nucleotide and inhibits the action of HIV-1 reverse transcriptase. Thus, the active HIV molecule becomes inactive and further reproduction and multiplication process is stopped.

Heptavir (Lamivudine (10mg)) syrup inhibits the action of HIV-1 reverse transcriptase enzyme by incorporating themselves into the nucleotide sequence thus inhibits the action of the reverse transcriptase of HIV-1, thereby preventing the formation of mature virus particles into infectious virions that spreads the infection and improves immunity.

Absolute contraindications:

• if you are allergic to Heptavir (Lamivudine (10mg)) syrup
• if you have a liver disorder like hepatitis B or C or Child-Pugh disease
• if you have pancreatitis
• if you have renal diseases

Relative contraindication:

• if you are pregnant
• if you are diabetic

Common side effects that occur 1:10 patients: Headache, insomnia, Cough, nausea, vomiting, abdominal pain or cramps, diarrhea, Rash, alopecia, Arthralgia, Fatigue, malaise, fever.

Uncommon side effects that occur 1:100 patients: Neutropenia and anemia, thrombocytopenia, raise in AST, ALT levels

Rare side effects that occur 1:1000 patients: Pure red cell aplasia, Lactic acidosis, Pancreatitis, elevations in serum amylase, Hepatitis, Angioedema, Rhabdomyolysis

Very rare side effects that occur 1:10,000 patients: Peripheral neuropathy

Is Heptavir (Lamivudine (10mg)) syrup safe during pregnancy?

Yes, taking Heptavir syrup during pregnancy has decreased the transmission of HIV from mother to fetus. Consult your physician.

Can Heptavir syrup be taken while breastfeeding?

No, in general HIV virions can pass via breastfeeding thus it is suspected that antivirals can also pass via breastfeeding.

Can Heptavir syrup be taken while alcohol consumption?

The interaction is unknown but this medication causes side effects. Thus, consult your physician.

Can I take a drive or operate heavy machineries while on Heptavir syrup?

This medication causes side effects thus caution is used while driving or operating machineries.

Can Heptavir syrup be taken as monotherapy in HIV treatment?

No, Heptavir syrup must be taken with other antivirals.

Alcohol

Heptavir (Lamivudine (10mg)) syrup generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

Driving or operating machinery

It is preferred to drive or operate heavy machinery with caution as Heptavir (Lamivudine (10mg)) syrup causes side effects. For further queries, consult your physician.

Pregnancy

The use of Heptavir (Lamivudine (10mg)) syrup is recommended during pregnancy.

Breast Feeding

The use of Heptavir (Lamivudine (10mg)) syrup during breastfeeding is not recommended as evidence shows less amount of the medication passes via breastfeeding to the baby that may cause adverse effect in newborn.

Kidney Problem

Renal filtration impairment – monitor function. For further queries, consult your physician.

Liver Disease

Liver disorders and diseases like hepatitis B or C, Child Pugh disease

Monitor liver function before and during therapy, especially in patients with other

Heptavir (Lamivudine (10mg)) syrup must be taken with other antivirals as prescribed by the physician without fail. These medicines must be taken with or without food on a regular time basis.

Heptavir (Lamivudine (10mg)) syrup has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.

• Skin reactions - It can be mild to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.
• Musculoskeletal problems - Osteonecrosis that causes joint stiffness and pain in larger joints like shoulder, hip, and knee
• New onset diabetes mellitus or hyperglycemia – Monitor blood glucose and insulin levels. When needed add oral hypoglycemic and insulin
• Accumulation or Redistribution of body fat or
• immune reconstitution syndrome.
• Any sign of infection – fever or lymph node enlargement

If you have any allergy

If you have a liver problem

If you have a kidney problem

If you are pregnant or breastfeeding

Heptavir (Lamivudine (10mg)) syrup is taken with other antivirals orally as prescribed dosage at specific time regularly.

Drug-Drug Interaction

Serum concentration decreased by Acetazolamide, Potassium citrate

Serum concentration increased by Aceclofenac, Acetaminophen, Alprazolam

severity of adverse effects is increased by Acyclovir, Amphotericin B, Baclofen

Drug-Food Interaction

Heptavir (Lamivudine (10mg)) syrup can be safely taken with any type of food, if doubts arise kindly refer to your physician. Heptavir syrup generally causes side effects thus it is advised not to be taken with alcohol.

Drug-Disease Interaction

• Liver disorders – used with caution in severe liver diseases. Consult a physician before use
• Kidney disorders – used with caution in severe kidney diseases. Consult a physician before use
• Cardiac disorders – used with caution in heart failure and MI. Consult a physician before use
• Respiratory disorders – used with caution in respiratory distress. Consult a physician before use
• Pancreases disorders – used with caution in pancreatitis. Consult a physician before use

Contact your doctor, pharmacist, or nurse immediately.

If you take once a day dosage, then the missed dosage if you notice within 12 hours. If it is more than 12 hours, then skip the dosage and take the next doses as usual. If you take twice a day dosage, then the missed dosage if you notice within 6 hours. If it is more than 6 hours, then skip the dosage and take the next doses as usual. Always take with other antivirals Don’t take a double dose for a forgotten dose.

Keep the medication out of children’s reach

Keep the medication away from pets

Once expired dispose immediately

Store at 30°C

Heptavir syrup contains Lamivudine 10mg.

It is a nucleoside reverse transcriptase inhibitor.

It is used to control and treat HIV infection with other antivirals

Do not use this medication while the lactation period.

Don’t use this medication with liver disease and kidney diseases.

This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury, etc.