Hertab 250mg Tablet 30s Pack

Brand Name Hertab 250mg Tablet 30s Pack
Salt Composition

Lapatinib (250mg)

Strength 250mg
Product Form Tablet
Pack 30 Tablet(s) in Bottle
Storage Store below 30°C
Category

Anti-Cancer

SubCategory

Breast Cancer

Country of Origin India
Manufacturer

Hetero Drugs Limited

Manufacturer/Marketer Address Hetero Drugs Limited,Hetero House, H. No. 8-3-166/7/1, Erragadda, Hyderabad, Andhra Pradesh, 500018 India
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Hertab 250mg Tablet, Lapatinib, price, uses, side effects - Drugcarts watermark
M.R.P : Rs.6545.00       Price : Rs.3861.55

You Save : Rs.2,683.45    Inclusive of all taxes

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30 Tablet(s) in Bottle

Availability : In Stock


    Medical Description of Hertab 250mg Tablet 30s Pack

    Hertab 250mg Tablet contains Lapatinib 250mg used to treat breast cancer by inhibiting the growth of cancer cell and it also used along with other combination to cure advanced-stage breast cancer. It shrinks and stops the progression of abnormal cancer cells. This medication is recommended only for adults.


    Hertab 250mg Tablet 30s Pack Uses

    It is used in the treatment of the following conditions as breast cancer.


    Hertab 250mg Tablet 30s Pack Benefits

    Breast cancer

    It is a type of cancer that forms in the breast cells. It is common among women. Symptoms include breast lump, change in breast size, redness, pitting of the skin, color change, and peeling surrounding the breast skin or nipple. This medicine helps to inhibit the multiplication of cancer cells.


    Hertab 250mg Tablet 30s Pack Indication

    The Hertab 250mg Tablet is prescribed in the following indications as breast cancer and it also used as an orphan drug for treatment of gastric and esophageal cancer.


    Mechanism of action of Hertab 250mg Tablet 30s Pack

    Hertab 250mg Tablet contains Lapatinib 250mg is an anti-cancer agent called atyrosine kinase inhibitor. It produces its effect by attaching to epidermal growth factor receptors type 1 and 2. Lapatinib 250mg inhibits signalling process required for angiogenesis and proliferation of abnormal cells are inhibited.  It shrinks the abnormal cells and minimises metastasis thus treats and controls cancers or tumors.


    How Hertab 250mg Tablet 30s Pack works

    Hertab 250mg Tablet contains Lapatinib 250mg is an anti-cancer agent called tyrosine kinase inhibitor. It produces its effect by inhibiting the human epidermal growth factor receptor protein receptor and epidermal growth factor receptor which are responsible for over-production of cells and it also inhibit the growth of cancer cells that cause downstrean signaling pathways.


    Hertab 250mg Tablet 30s Pack Contraindication

    • Do not take this medicine if you are allergic to Lapatinib
    • It is contraindicated to use this medicine in patients who are having a cardiac disorder


    Hertab 250mg Tablet 30s Pack Side Effects

    • Diarrhea
    • Anemia
    • Increased Lived function test
    • Rash
    • Vomiting, nausea
    • Pain
    • Neutropenia
    • Thrombocytopenia
    • Mucositis
    • Stomatitis
    • Dyspnea
    • Dyspepsia
    • Insomnia


    FAQs for Hertab 250mg Tablet 30s Pack

    • Can Hertab 250mg Tablet be given in combination with other anti-cancer drug?

    Yes, this medicine can be used along with other anticancer drug Capecitabine to treat advanced breast cancer in patients who are having who are already treated with chemotherapy. It is also used along with letrozole to treat breast cancer in post-menopausal women.

    • How should I manage diarrhea while taking Hertab 250mg Tablet?

    If you are suffering from diarrhea drink plenty of fluids like water, sports drink, or clear liquids. You should eat low-fat, high protein rich foods instead of fatty and spicy foods. Kindly avoid consuming milk and milk products.

    • How long after Hertab 250mg Tablet can I plan pregnancy?

    Use effective contraceptive to avoid pregnancy while you are receiving this medicine for at least one week after the last dose.


    Precautions and general warning of Hertab 250mg Tablet 30s Pack

    Alcohol

    It is not clear that consuming alcohol is safe while you are receiving this medicine. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor

    Kidney Problem

    The medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    The medicine should be used with caution in patients with hepatic impairment. The use of this medicine required dose modification. Kindly consult with your doctor.


    How to Take Hertab 250mg Tablet 30s Pack

    Hertab 250mg Tablet is taken orally with or without food. You should not chew, cut or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Hertab 250mg Tablet 30s Pack in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor


    Use of Hertab 250mg Tablet 30s Pack in children

    Safety and efficacy were not established in children who are below 18 years old. Kindly consult with your doctor.


    Use of Hertab 250mg Tablet 30s Pack in Elderly Patients

    Hertab 250mg Tablet should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The use of this medicine may cause diarrhea
    • Therapy should be administered with caution in patients who are having a history of severe hepatic impairment
    • The useof lapatinib along with QT-prolonging drug may increase the risk for developing QT-prolongation
    • The use of this medicine may cause severe cutaneous reactions
    • ‘The use of this medicine may decrease the left ventricular ejection fraction
    • The use of this medicine may increase the risk for developing interstitial lung disease and pneumonitis and cardiac events


    Talk to your doctor if

    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have a receiving any concomitant medication and disease


    General instructions

    Lapatinib 250mg used to treat breast cancer. Lapatinib 250mg is an anti-cancer agent called tyrosine kinase inhibitor. It produces its effect by inhibiting the human epidermal growth factor receptor protein receptor and epidermal growth factor receptor which are responsible for over-production of cells and it also inhibit the growth of cancer cells that cause downstrean signaling pathways.

     


    Drug Interaction of Hertab 250mg Tablet 30s Pack

    Drug-Drug Interaction

    Dihydroergotamine

    The use of this medicine is contraindicated because the us of lapatinib will increase the effect of dihydroergotamine by affecting its hepatic and intestinal enzyme metabolism

    Everolimus

    The use of this medicine is contraindicated because the use of lapatinib will increase the effect of everolimus by P-glycoprotein efflux transporter.

    Pimozide

    The use of this medicine is contraindicated because the use of lapatinib will increase the effect of pimozide by decreasing its metabolism and it also increase the risk for developing QT interval prolongation

    Amiodarone

    Use alternative drug because the combination of this medicine increase QTc interval

    Apalutamide

    Therapy should be admi9nstered with caution because the use of apalutamide decrease the effect of lapatinib by increasing its metabolism.

    Cimetidine

    Therapy should be administered with caution because the use of cimetidine will decrease the effect of laptinib by increasing its gastric Ph.

    Drug-Food Interaction

    Lapatinib 250mg should be taken on an empty stomach one hour before the meal or 2 hours after the meal. You should also avoid grapefruit juice while you are receiving this medicine it may increase the Lapatinib in blood levels.

    Drug-Disease Interaction

    Cardiomyopathy

    Therapy should be administered with caution in patients who are having a history of left ventricular function because the use of EGFR inhibitor may cause cardiomyopathy

    Dermatologic toxicities

    The use of EGFR inhibitors may cause cutaneous reaction. Kindly wear sunscreen and hats to avoid sun exposure while receiving this therapy

    Pulmonary toxicity

    Therapy should be administered with caution in patients with a history of interstitial pneumonitis and pulmonary fibrosis, pulmonary symptoms such as dyspnea, cough  and fever because the use of EGFR inhibitors itself associated with pulmonary toxicity.

    Thrombocytopenia

    Patients who are having a history of decreased platelet count and patients on anti-coagulant treatment because the use of this medicine may cause thrombocytopenia

    Congestive heart failure

    Therapy should be administered with caution in patients who are having a history of previous heart conditions because the use of this medicine may decrease the left ventricular ejection fraction and cause congestive heart failure.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.

     


    Fast Tag

    • Hertab 250mg Tablet contains Lapatinib 250mg used to treat breast cancer by inhibiting the growth of cancer cell and it also used along with other combination to cure advanced-stage breast cancer. It shrinks and stops the progression of abnormal cancer cells. This medication is recommended only for adults.
    • Take this medicine 1 hour before or 2 hours after your meal
    • The use of this medicine can make your skin sensitive so apply sunscreen and wear protective clothing
    • Kindly inform your doctor if you have experienced headache, stomach pain and blood in your stool and urine while you are receiving this medicine.