Inbec Tablet 30s Pack

Brand Name Inbec Tablet 30s Pack
Salt Composition Abacavir (600mg) + Dolutegravir (50mg) + Lamivudine (300mg)
Strength 600mg + 50mg + 300mg
Product Form Tablet
Pack 30 Tablet(s) in 1 Bottle
Storage Store at room temperature (10-30°C)
Category HIV
Country of Origin India
Manufacturer Emcure Pharmaceuticals Ltd
Manufacturer/Marketer AddressEmcure Pharmaceuticals Ltd, 255/2, Hinjawadi, Pune - 411057, India.
-15%
Viropil Tablet, Abacavir 600mg, Dolutegravir 50mg, Lamivudine 300mg, Price, Uses, Side Effects - Drugcarts watermark
M.R.P : Rs.5307.45       Price : Rs.4511.33

You Save : Rs.796.12    Inclusive of all taxes

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30 Tablet(s) in 1 Bottle

Availability : In Stock

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    Medical Description of Inbec Tablet 30s Pack

    Inbec Tablet contains Abacavir 600mg, Dolutegravir 50mg and Lamivudine 300mg. Inbec tablet is an antiviral medicine used in the treatment of Human Immunodeficiency Virus (HIV) – 1 infection. Dolutegravir is an integrase strand transfer inhibitor. Lamivudine and Abacavir is a nucleoside analogue. This tablet combination works by reducing the viral load of HIV in your body &  improves your immune system to reduces the risk of conditions associated with HIV infection. 


    Inbec Tablet 30s Pack Uses

    Inbec tablet is used to treat adults and adolescence above the weight class 40kg only who are infected by HIV-1.


    Inbec Tablet 30s Pack Benefits

    Inbec tablet is used to help control HIV infection. This tablet helps to decrease the amount of HIV in your body thus your immunity works better by reducing your chance of getting HIV complications like co-infections and other cancers. Inbec tablet is not a cure for HIV infection, it improves immunity that results in longevity of life. It is recommended for use in children from 40kgs and in adults.


    Inbec Tablet 30s Pack Indication

    Inbec tablet is indicated in the treatment of HIV-1 infection that causes AIDS in humans. It boosts the immunity of the affected hosts and is indicated in adults and children above 40kgs. Caution is used in the case of HLA-B5701 allele carriers and hepatitis B virus.


    Mechanism of action of Inbec Tablet 30s Pack

    Inbec tablet combination dolutegravir is a inhibits strand transfer activity of integrase in DNA thus blocks replication of HV-1. Lamivudine is an analogue that is phosphorylated to its active forms lamivudine triphosphate that is incorporated into the nucleotide and inhibits the action of HIV-1 reverse transcriptase. Abacavir is an analogue that is phosphorylated to its active forms lamivudine triphosphate that is incorporated into the nucleotide and inhibits the action of HIV-1 reverse transcriptase. Thus, the active HIV molecules become inactive and further reproduction and multiplication process is stopped.


    How Inbec Tablet 30s Pack works

     Dolutegravir inhibits the transfer of integrase in DNA and Lamivudine and abacavir incorporates themselves into the DNA thus stops the replication of viral particles. Thereby preventing the formation of mature virus particles into infectious virions that spreads the infection.


    Inbec Tablet 30s Pack Contraindication

    Absolute contraindications:

    • if you are allergic to Inbec (Abacavir (600mg) + Dolutegravir (50mg) + Lamivudine (300mg)) tablet and its contents
    • if you are HLA-B5701 allele carrier
    • if you are pregnant
    • if you are breastfeeding
    • if you have kidney disease

    Relative contraindications:

    • if you have a liver disease like hepatitis B or C
    • if you are diabetic
    • if you have a bleeding disorder like haemophilia
    • if you have heart diseases


    Inbec Tablet 30s Pack Side Effects

    Very common side effects that occurs in more than 1:10 patients: headache, diarrhoea, nausea, hypersensitivity

    Common side effects that occur 1:10 patients: pruritus, vomiting, abdominal pain, flatulence, insomnia, abnormal dreams, depression dizziness, tiredness, changes in LFT and increased creatine kinase, insomnia, Cough, vomiting, abdominal pain or cramps, Rash, alopecia, Arthralgia, Fatigue, malaise, fever, hypophosphataemia, asthenia, alopecia, hyperlactataemia

    Uncommon side effects that occur 1:100 patients: hepatitis, suicidal thoughts and behaviours, joint and muscle pain, Neutropenia and anaemia, thrombocytopenia, hypokalaemia, proximal renal tubulopathy 

    Rare side effects that occur 1:1000 patients: osteonecrosis, Pure red cell aplasia, Lactic acidosis, Peripheral neuropathy, Rhabdomyolysis, pancreatitis, cardiomyopathy, convulsions, rhabdomyolysis, raise in AST and ALT levels

    Very rare side effects that occur 1:10,000 patients: erythema multiform, Stevens-Johnson syndrome, toxic epidermal necrolysis, lactic acidosis, pure red cell aplasia, paresthesia


    FAQs for Inbec Tablet 30s Pack

    Is Inbec (Abacavir (600mg) + Dolutegravir (50mg) + Lamivudine (300mg)) tablet safe during pregnancy?

    No, Inbec tablet is not safe during pregnancy. Consult your physician.

    Can Inbec tablet be taken while breastfeeding?

    No, in general HIV virions can pass via breastfeeding thus it is suspected that antivirals can also pass via breastfeeding.

    Can Inbec tablet be taken while alcohol consumption?

    The interaction is unknown but this medication causes side effects. Thus, consult your physician.

    Can I take a drive or operate heavy machineries while on Inbec tablet?

    This medication causes side effects thus caution is used while driving or operating machineries.

    Can Inbec tablet be taken as a prophylactic to exposure?

    No, Inbec tablet cannot be taken as a prophylactic.


    Precautions and general warning of Inbec Tablet 30s Pack

    Alcohol

    Inbec tablet generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

    Driving or operating machinery

    It is preferred to drive or operate heavy machinery with caution as Inbec tablet causes side effects. For further queries, consult your physician.

    Pregnancy

    The use of Inbec tablet is not recommended during pregnancy.

    Breast Feeding

    The use of Inbec tablet during breastfeeding is not recommended as evidence shows less amount of the medication passes via breastfeeding to the baby that may cause adverse effect in newborn.

    Kidney Problem

    Renal filtration impairment and kidney stone formation – monitor function. For further queries, consult your physician.

    Liver Disease

    Liver disorders and diseases like hepatitis B or C, Child-Pugh disease

    Monitor liver function before and during therapy, especially in patients with other


    How to Take Inbec Tablet 30s Pack

    Inbec (Abacavir (600mg) + Dolutegravir (50mg) + Lamivudine (300mg)) tablet is taken with food at regular time.

    Inbec tablet should not be crushed or chewed it must be swallowed.

    After therapy has been initiated, do not take more or less of Inbec than prescribed or stop taking it without your physicians’ approval. Skipping or changing Inbec tablet dose without approval may cause the amount of the virus to increase making the infection more difficult to treat, or worsen side effects.


    Use of Inbec Tablet 30s Pack in Adult

    If you are pregnant or breastfeeding inform your physician as they are not advisable.

    The recommended dosage for Inbec (Abacavir (600mg) + Dolutegravir (50mg) + Lamivudine (300mg)) tablet is one tablet taken once per day

    These medicines must be taken with food on a regular time basis.


    Use of Inbec Tablet 30s Pack in children

    The recommended dosage of Inbec (Abacavir (600mg) + Dolutegravir (50mg) + Lamivudine (300mg)) tablet above this weight class is one tablet taken once per day.


    Use of Inbec Tablet 30s Pack in Elderly Patients

    Inbec (Abacavir (600mg) + Dolutegravir (50mg) + Lamivudine (300mg)) tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.


    Other general warnings

    • New onset diabetes mellitus or hyperglycemia – Monitor blood glucose and insulin levels. When needed add oral hypoglycemic and insulin
    • Blood disorders Hemophilia, hemolytic anemia
    • Skin reactions - It can be mild to severe like Stevens-Johnson syndrome and toxic epidermal necrolysis.
    • Musculoskeletal problems - Osteonecrosis that causes joint stiffness and pain in larger joints like shoulder, hip, and knee
    • Accumulation or Redistribution of body fat or
    • Immune reconstitution syndrome.
    • Any sign of infection – fever or lymph node enlargement
    • Lactose intolerance or galactose malabsorption


    Talk to your doctor if

    If you have any allergy

    If you have HLA-B5701 allele

    If you have a blood disorder

    If you are pregnant or breastfeeding


    General instructions

    Inbec (Abacavir (600mg) + Dolutegravir (50mg) + Lamivudine (300mg)) tablet is an antiviral taken orally as a prescribed dosage at the specific time regularly with food.


    Drug Interaction of Inbec Tablet 30s Pack

    Drug-Drug Interaction

    Metabolism increased by Carbamazepine, Oxcarbazepine, Phenytoin, Phenobarbital

    Metabolism decreased by Ketoconazole, Fluconazole, Itraconazole

    Serum concentration increased by Clarithromycin, fluconazole, amphotericin B, Aceclofenac

    Serum concentration decreased by - Hydrochlorothiazide, Isosorbide

    Efficacy is decreased by - methadone

    Decreased absorption caused by Magnesium/aluminum-containing antacid

    Risk of cytopenia increased when combined with – Ganciclovir

    St. John's wort

    Drug-Food Interaction

    Inbec tablet can be safely taken with food, if doubts arise kindly refer to your physician. This tablet generally causes side effects thus it is advised not to be taken with alcohol.

    Drug-Disease Interaction

    • Liver disorders – used with caution in severe liver diseases. Consult physician before use
    • Kidney disorders – used with caution in severe kidney diseases. Consult physician before use
    • Cardiac disorders – used with caution in heart failure and MI. Consult physician before use
    • Respiratory disorders – used with caution in respiratory distress. Consult physician before use
    • Blood disorders – used with caution in anemia and hemophilia. Consult physician before use


    Over Dose

    Contact your doctor, pharmacist or nurse immediately.


    Missed Dose

    In general, if you take once a day dosage, the missed single dose of Inbec tablet can be taken within the next 12 hrs, you can take it. If it is more than 12 hrs, skip the dose and take the next dose at the recommended time. Don’t take a double dose for a forgotten dose.


    Storage and Disposal

    Keep the medication out of children’s reach

    Keep the medication away from pets

    Once expired dispose immediately

    Store at 30°C


    Fast Tag

    Inbec  tablet reverses transcriptase and integrase inhibitor.

    Inbec tablet is used to control and treat HIV infection.

    Do not use this medication while pregnant or lactation period.

    Don’t use this medication with liver disease and kidney diseases.

    This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury, etc.