Innotubilin 20mg Injection

Brand Name Innotubilin 20mg Injection
Salt Composition Docetaxel (20mg)
Strength 20mg
Product Form Injection
Pack 0.5ml in 1 Vial
Category Anti-Cancer
Country of Origin India
Manufacturer Innova Formulations Pvt Ltd
Manufacturer/Marketer AddressInnova Formulations Pvt Ltd, INNOVA HOUSE, Plot No- 1020 , Behind Metro Depot, Mundka, New Delhi-41, India – 110041
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M.R.P : Rs.2022.00       Price : Rs.1617.60

You Save : Rs.404.40    Inclusive of all taxes

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0.5ml in 1 Vial

Availability : In Stock

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    Medical Description of Innotubilin 20mg Injection

    Innotubilin 20mg Injection contains Docetaxel 20mg used to treat breast cancer, non-small cell lung cancer, gastric cancer, head and neck cancer, and prostate cancer. Docetaxel helps to inhibit the growth and multiplication of cancer cells. Do not self administer this medicine.


    Innotubilin 20mg Injection Uses

    It is used in the treatment of the following conditions as breast cancer, non-small cell lung cancer, gastric cancer, head and neck cancer, and prostate cancer.


    Innotubilin 20mg Injection Benefits

    Breast cancer

    It is a type of cancer that forms in the breast cells. It is common among women. Symptoms include breast lump, change in breast size, redness, pitting of the skin, color change, and peeling surrounding the breast skin or nipple. This medicine helps to inhibit the multiplication of cancer cells.

    Non-small cell lung cancer

    It is the common type of lung cancer and it grows, spreads slowly when compared with small lung cell cancer. Smoking is the common cause of non-small cell lung cancers. Symptom includes fatigue, weight loss, shortness of breath, loss of appetite, coughing up with cough or phlegm, and cough. This medicine helps to inhibit the multiplication of cancer cells.

    Gastric cancer

    It is an abnormal growth of cells that starts in the stomach. Stomach cancer is also called gastric cancer it will affect any part of your stomach. Symptoms include difficulty in swallowing, bloating, heartburn, indigestion, stomach pain, weight loss, and vomiting. This medicine helps to inhibit the multiplication of cancer cells.

    Head and Neck cancer

    It is also called throat cancer. Alcohol and Smoking are considered major risk factors for head and neck cancer. Symptoms include swelling in the jaw, lump, trouble in speaking and breathing, pain in ears, headache, nose bleeding, and pain in the upper teeth. This medicine helps to inhibit the multiplication of cancer cells.

    Prostate cancer

    It is cancer that occurs in a man’s prostate. Usually, it grows slowly and is confined to the prostate gland. Symptoms include difficulty in urinating, blood in urine, semen, bone pain, weight loss, and erectile dysfunction. This medicine helps to inhibit the multiplication of cancer cells.


    Innotubilin 20mg Injection Indication

    The Innotubilin injection is prescribed in the following indications as

    • Breast cancer which is locally advanced or metastatic and failure to respond to chemotherapy
    • Non-small cell lung cancer which is locally advanced or metastatic and failure to respond to platinum-based chemotherapy
    • Advanced gastric adenocarcinoma
    • Advanced adenocarcinoma of the gastroesophageal junction
    • Head and neck cancer which is locally advanced squamous cell carcinoma
    • Metastatic Prostate cancer is hormone-based


    Mechanism of action of Innotubilin 20mg Injection

    Innotubilin 20mg Injection contains Docetaxel 20mg is an anti-cancer agent called Antimicrotubular inhibitor that produces its action by interfering in the function of the growth phase of microtubules at G2/M phase of cell cycle disrupting mitotic spindle formation and apoptosis is induced. 


    How Innotubilin 20mg Injection works

    Innotubilin 20mg Injection contains Docetaxel 20mg is an anti-cancer agent called Antimicrotubular inhibitor that produces its action by interfering in the function of the growth phase of microtubules at G2/M phase of cell cycle disrupting mitotic spindle formation and apoptosis is induced. 


    Innotubilin 20mg Injection Contraindication

    • Do not take this medicine if you are allergic to Docetaxel
    • It is contraindicated to use this medicine in patients with solid tumors, AIDS-related Kaposi’s sarcoma with neutrophils count less than 1,500 cells/mm3


    Innotubilin 20mg Injection Side Effects

    • Alopecia
    • Anemia
    • Leukopenia
    • Neutropenia
    • Infections
    • Fluid retention
    • Hypersensitivity
    • Diarrhea
    • Sensory neuropathy
    • Myalgia
    • Thrombocytopenia


    FAQs for Innotubilin 20mg Injection

    • What blood tests are required before administration of Innotubilin 20mg Injection?

    Before initiating the treatment with Innotubilin you may be asked to have blood tests, liver function tests.

    • Why is dexamethasone used with Innotubilin 20mg Injection?

    The use of this medicine may cause fluid retention and severe hypersensitivity so to control this effect the patients are given corticosteroids for 3 days.

    • Is hair loss caused by Innotubilin 20mg Injection irreversible?

    Hair loss is the common side effect of this medicine but it may get reversed as soon as you stopped taking this injection. Kindly consult with your doctor in cases there is permanent hair loss


    Precautions and general warning of Innotubilin 20mg Injection

    Alcohol

    The use of alcohol may produce harmful effects while you are receiving this treatment. Kindly consult with your doctor.

    Driving or operating machinery

    It is not clear that receiving this medicine will affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor

    Kidney Problem

    It is considered safe to use this medicine in patients who are having a renal impairment. Kindly consult with your doctor.

    Liver Disease

    The medicine should be used with caution in patients with hepatic impairment. The use of this medicine required dose modification. Kindly consult with your doctor.


    How to Take Innotubilin 20mg Injection

    Innotubilin 20mg Injection comes in a liquid solution as an intravenous injection. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Innotubilin 20mg Injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor


    Use of Innotubilin 20mg Injection in children

    Safety and efficacy were not established in children who are below 18 years old. Kindly consult with your doctor.


    Use of Innotubilin 20mg Injection in Elderly Patients

    Innotubilin 20mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The patients who are receiving this injection for breast cancer sepsis were reported
    • The patients who are having abnormalities of transaminases and alkaline phosphatase should not be treated with docetaxel
    • The use of this medicine may cause enterocolitis and neutropenic colitis, severe fluid retention, second primary malignancies, cystoids macular edema, severe asthenia, and Tumor lysis syndrome were reported.
    • In gastric cancer patients, a combination of docetaxel, cisplatin, and fluorouracil febrile neutropenia and neutropenic infection were reported.


    Talk to your doctor if

    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have a receiving any concomitant medication and disease

     


    General instructions

    Docetaxel 20mg is used to treat breast cancer, non-small cell lung cancer, gastric cancer, head and neck cancer, and prostate cancer. Docetaxel is an anti-cancer agent called an Antimicrotubular inhibitor that produces its action by interfering in the function of the growth phase of microtubules at the G2/M phase of the cell cycle disrupting mitotic spindle formation and apoptosis is induced. 


    Drug Interaction of Innotubilin 20mg Injection

    Drug-Drug Interaction

    Apalutamide

    Use alternative drugs because the use of apalutamide will decrease the effect of docetaxel by affecting hepatic and intestinal enzyme metabolism.

    Deferiprone

    Use alternative drugs because the combination of this medicine either increases the toxicity of the other by pharmacodynamic synergism.

    Amiodarone

    Therapy should be administered with caution because the use of amiodarone will increase the effect of docetaxel by P-glycoprotein efflux transporter.

    Cannabidiol

    Therapy should be administered with caution because the use of cannabidiol will increase the effect of docetaxel by decreasing its metabolism

    Ketoconazole

    Therapy should be administered with caution because the use of ketoconazole will increase the level of docetaxel by affecting its hepatic and intestinal enzyme metabolism.

    Drug-Food Interaction

    Kindly avoid consuming grapefruit juice while you are receiving this medicine it may increase the blood level of docetaxel and also increase the risk of side effects such as nausea, diarrhea, hair loss, muscle pain, weakness, nerve damage, and impaired bone marrow functions.

    Drug-Disease Interaction

    Infections

    The use of this medicine is contraindicated in patients with infectious diseases because of their cytotoxic effect it induces myelosuppression.

    Hepatic dysfunction

    Therapy should be administered with caution in patients with hepatic impairment because the use of this medicine may increase the risk of developing hepatotoxicity.

    Myelosuppression

    Therapy should be not be administered in patients who are having a neutrophil count less than 1500/mm3 because docetaxel may induce dose-dependent myelosuppression.

    Eye disorders

    Therapy should be administered with caution in patients with eye disorders because the use of this medicine may cause cystoids macular edema so before initiating the treatment kindly undergo ophthalmologic examination.

    Edema

    Therapy should be administered with caution in patients with fluid retention because the use of this medicine may cause severe fluid retention  like peripheral edema, generalized edema, pleural effusion, dyspnea, and abdominal distention


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    Innotubilin 20mg Injection contains Docetaxel 20mg used to treat breast cancer, non-small cell lung cancer, gastric cancer, head and neck cancer, and prostate cancer. Docetaxel helps to inhibit the growth and multiplication of cancer cells. Do not self administer this medicine.

    Kindly inform your doctor if you have experienced bleeding, sore throat, mouth ulcers, fever, and other infections.