Isentress 400mg Tablet

Brand Name Isentress 400mg Tablet
Salt Composition Raltegravir (400mg)
Strength 400mg
Product Form Tablet
Pack 60 Tablet(s) in Bottle
Storage Store at room temperature (10-30°C)
Category HIV
Country of Origin India
Manufacturer MSD Pharmaceuticals Pvt Ltd
Manufacturer/Marketer AddressMSD Pharmaceuticals Pvt Ltd,Platina, 8th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) , Mumbai - 400098,
-20%
Isentress 400mg Tablet, Raltegravir 400mg, price, Uses, Side Effects - Drugcarts watermark
M.R.P : Rs.8689.00       Price : Rs.6951.20

You Save : Rs.1,737.80    Inclusive of all taxes

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Availability : In Stock


    Medical Description of Isentress 400mg Tablet

    Isentress Tablet contains Raltegravir 400mg. Isentress (Raltegravir (400mg)) tablet is an antiviral medicine used in the treatment of HIV-1 infection. Isentress tablet is an HIV-1 integrase inhibitor. Isentress tablet is used in combination with other antivirals to treat HIV. Isentress tablet is also used in treatment as post-exposure for occupational exposure to HIV therapy.


    Isentress 400mg Tablet Uses

    Isentress (Raltegravir (400mg)) tablet is used to treat adults and children above 2 years of age or weight class above 10 Kgs who are infected by HIV-1 infection. Isentress tablet should be taken with other anti-HIV medications.


    Isentress 400mg Tablet Benefits

    Isentress (Raltegravir (400mg)) tablet is used to treat HIV-1 infection. Isentress tablet is an HIV-1 integrase inhibitor. Isentress tablet is not a cure for HIV infection, it helps manage and treat HIV. Isentress tablet improves the immune system thus prevents co-infection and cancers. Isentress tablet is not recommended for use in children less than 2 years of age or weight lesser than 10 Kgs due to the increased risk of serious side effects.


    Isentress 400mg Tablet Indication

    Isentress (Raltegravir (400mg)) tablet is indicated in the treatment of HIV-1 infection. Isentress tablet is co-administered safely with other antivirals for HIV. Isentress tablet is indicated in ages above 2 years of age or weight above 10Kgs. Caution is used in the case of diagnosed phenylketonuria.


    Mechanism of action of Isentress 400mg Tablet

    Isentress (Raltegravir (400mg)) tablet is an integrase inhibitor. Isentress tablet acts as an inhibitor of HIV-1 catalytic activity. Thus inhibits the replication of virus. Thus, in combination with other antivirals.


    How Isentress 400mg Tablet works

    Isentress (Raltegravir (400mg)) tablet is an HIV-1 integrase inhibitor. Isentress tablet inhibits the action of HIV-1 viruses’ catalytic action, thereby preventing the formation of mature virus particles. Thus, controls HIV infection and improves immunity.


    Isentress 400mg Tablet Contraindication

    Absolute contraindication:

    • if you are allergic to Isentress (Raltegravir (400mg)) tablet
    • if you are lactating
    • if you are pregnant

    Relative contraindication:

    • if you have renal diseases like phenylketonuria
    • if you have mental disorders
    • if you are diabetic
    • if you have liver diseases


    Isentress 400mg Tablet Side Effects

    Very common side effects that occur 1:10 patients: Rash, nausea, vomiting, abdominal pain, diarrhea, somnolence

    common side effects that occur 1:100 patients: headache, insomnia, fatigue, dizziness, dyspepsia, and increased liver enzymes, Decreased levels of neutrophils

    uncommon side effects that occur 1:1000 patients: rash, hair loss, hematuria, jaundice, osteonecrosis, severe allergic reaction, lactic acidosis


    FAQs for Isentress 400mg Tablet

    Is Isentress (Raltegravir (400mg)) tablet safe during pregnancy?

    No, taking Isentress tablet during pregnancy is not recommended. Consult your physician.

    Can Isentress tablet be taken while breastfeeding?

    No, taking Isentress tablet is not recommended during breast feeding. Consult your physician.

    Can Isentress tablet be taken while alcohol consumption?

    The interaction is unknown but this medication causes side effects. Thus, consult your physician.

    Can I take a drive or operate heavy machineries while on Isentress tablet?

    This medication causes side effects thus caution is used while driving or operating machineries.

    Can Isentress tablet be taken as monotherapy for HIV?

    No, Isentress tablet is used with other antivirals that treat HIV infection


    Precautions and general warning of Isentress 400mg Tablet

    Alcohol

    Isentress (Raltegravir (400mg)) tablet generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

    Driving or operating machinery

    It is preferred to drive or operate heavy machinery with caution as Isentress (Raltegravir (400mg)) tablet causes side effects. For further queries, consult your physician.

    Pregnancy

    The use of Isentress (Raltegravir (400mg)) tablet is not recommended during pregnancy.

    Breast Feeding

    The use of Isentress (Raltegravir (400mg)) tablet during breastfeeding is not recommended.

    Kidney Problem

    Like phenylketonuria – monitor function. For further queries, consult your physician.

    Liver Disease

    Like hepatitis B or C

    Monitor liver function before and during therapy, especially in patients with other


    How to Take Isentress 400mg Tablet

    Isentress (Raltegravir (400mg)) tablet is taken orally without food for best result.

    Isentress tablet must be taken at the same time once a day as prescribed by your physician.

    Isentress tablet is always taken with other antivirals for treating HIV infection.

    After therapy has been initiated, do not take more or less of Isentress medicine than prescribed or stop taking it without your physicians’ approval. Skipping or changing Isentress tablet dose without approval may cause the amount of the virus to increase making the infection more difficult to treat, or worsen side effects.


    Use of Isentress 400mg Tablet in Adult

    If you are pregnant or breastfeeding inform your physician as they are not advisable.

    The recommended dosage of Isentress (Raltegravir (400mg)) tablet in HIV infection is 400mg taken orally twice per day

    Isentress tablet must be taken with other antivirals as prescribed by the physician without fail. These medicines must be taken with or without food on a regular time basis.


    Use of Isentress 400mg Tablet in children

    Isentress (Raltegravir (400mg)) tablet must be taken with other antivirals as prescribed by the physician without fail. These medicines must be taken with or without food on a regular time basis.


    Use of Isentress 400mg Tablet in Elderly Patients

    Isentress (Raltegravir (400mg)) tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.


    Other general warnings

    • Skin reactions - It can be mild to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.
    • New onset diabetes mellitus or hyperglycemia – Monitor blood glucose and insulin levels.
    • Immune reconstitution syndrome
    • Lactic acidosis
    • Rhabdomyolysis and myopathy


    Talk to your doctor if

    If you have any allergy

    If you have a liver problem

    If you have a kidney problem

    If you are diabetic

    If you are pregnant or breastfeeding


    General instructions

    Isentress (Raltegravir (400mg)) tablet is taken orally with or without food as prescribed dosage at a specific time regularly. It can be safely used in cases of HIV cases who are on a regime


    Drug Interaction of Isentress 400mg Tablet

    Drug-Drug Interaction

    Side Effects are increased by Atorvastatin, Ciprofloxacin, Ivermectin, Montelukast

    Serum concentration is decreased by Calcium carbonate, Ferrous, Zinc

    Absorption is increased by aluminium hydroxide, esmoprazole, ranitidine

    Drug-Food Interaction

    Isentress (Raltegravir (400mg)) tablet can be safely taken with any type of food, if doubts arise kindly refer to your physician. It generally causes side effects thus it is advised not to be taken with alcohol.

    Drug-Disease Interaction

    • Liver disorders – used with caution in severe liver diseases. Consult a physician before use
    • Kidney disorders – used with caution in severe kidney diseases. Consult a physician before use
    • Cardiac disorders – used with caution in heart failure and MI. Consult a physician before use
    • Respiratory disorders – used with caution in respiratory distress. Consult a physician before use


    Over Dose

    Contact your doctor, pharmacist or nurse immediately.


    Missed Dose

    If you take once a day dosage, then the missed dosage if you notice within 12 hours. If it is more than 12 hours, then skip the dosage and take the next doses as usual. If you take twice a day dosage, then the missed dosage if you notice within 6 hours. If it is more than 6 hours, then skip the dosage and take the next doses as usual. Always take with other antivirals Don’t take a double dose for a forgotten dose.


    Storage and Disposal

    Keep the medication out of children’s reach

    Keep the medication away from pets

    Once expired dispose immediately

    Store at 30?C


    Fast Tag

    Isentress (Raltegravir (400mg)) tabletcontains Raltegravir.

    Isentress tablet is an integrase inhibitor.

    Isentress tablet is used to control and treat HIV infection

    Do not use this medication while the lactation period.

    Don’t use this medication with liver disease and kidney diseases.

    This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury etc.