L Aspinase 5000IU Injection

L-Aspinase 5000IU Injection contains Asparaginase 5000IU used to treat Acute lymphocytic leukemia and Lymphoblastic lymphoma. It is an enzyme that works by interfering in the process which is required for the growth of cancer cells. It is used in combination with other cancer medications.

It is used in the treatment of the following conditions as acute lymphocytic leukemia and Lymphoblastic lymphoma.

Acute lymphoblastic leukemia

It is a cancer of blood and bone marrow that affects white blood cells. It usually occurs when a cell in bone marrow develops changes in its DNA. Symptoms include fever, joint pain, severe nosebleeds, pale skin, shortness of breath, fatigue, and bleeding from the gums.

Lymphoblastic lymphoma

It is a rare type of aggressive non-Hodgkins lymphoma mostly found in younger adults and teenagers. It usually occurs when your white blood cells become abnormal. It is associated with exposure to radiation, congenital or acquired immunosuppression. Symptoms include shortness of breath, cough, chest pain, weight loss, fever, and night sweats.

 

The L-Aspinase 5000IU Injection is prescribed in the following indications to treat acute lymphoblastic leukemia and Lymphoblastic lymphoma.

L-Aspinase 5000IU Injection contains Asparaginase 5000IU is an anti-cancer medication, it is a nonessential amino acid present in DNA and RNA structure and it is also derived from E. coli which leads to a decrease in levels of asparagine levels thus inhibiting DNA and RNA replication. Thus, causes the formation of an impaired DNA sequence containing abnormal cells where apoptosis occurs and results in cell death.

L-Aspinase 5000IU Injection contains Asparaginase 5000IU is an anti-cancer medication, It is enzymes that alter the natural process which is necessary for a cancer cell to grow which kills and inhibit the growth of cancer cells.

• Do not take this medicine if you are allergic to Asparaginase
• It is contraindicated to use this medicine in patients with serious pancreatitis, thrombosis, and hemorrhagic events during previous asparaginase therapy

• Abnormal liver test
• Nausea
• Fatigue
• Infection
• Headache
• Loss of appetite
• Bleeding
• Abdominal pain
• Tachycardia
• Diarrhea
• Constipation
• Dehydration
• Cough
• Insomnia

• How to get relief from diarrhea while on treatment with L-Aspinase 5000IU Injection?

Take the foods that help to absorb excess fluid from your body such as banana, orange, boiled potatoes, white rice, curd, and oatmeal. Drink plenty of water to avoid dehydration.

• Can the use of L-Aspinase 5000IU Injection cause hyperglycemia?

Yes, the use of this medicine may cause increased blood glucose levels. Kindly monitor the blood sugar level while you are in treatment.

• I am noticing swelling and frequent muscle cramps. Should I inform my doctor?

Yes, the use of this medicine may cause swelling and frequent muscle cramps this occurs due to a decreased level of albumin. Kindly monitor the patient albumin level in your body

Alcohol

It is not clear that consuming alcohol is safe while you are receiving this medicine. Kindly consult with your doctor.

Driving or operating machinery

It is considered safe to drive while you are receiving this medicine it does not affect your ability to drive. Kindly consult with your doctor.

Pregnancy

The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor

Breast Feeding

The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor

Kidney Problem

It is considered safe to use this medicine in patients who are with renal impairment. Kindly consult with your doctor.

Liver Disease

Limited information is available regarding the use of this medicine in patients who are with hepatic impairment. Kindly consult with your doctor.

L-Aspinase 5000IU Injection comes in a liquid solution as an intravenous and intramuscular. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.

It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.

 

It is considered unsafe to use this medicine in children who are below 1 year old. Kindly consult with your doctor.

L-Aspinase 5000IU Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.

• Therapy should be administered with caution in patients with pancreatitis, thrombotic events including sagittal sinus thrombosis and pulmonary embolism, bleeding, and hepatotoxicity were reported.
• The use of this medicine increases the risk of developing infection and glucose intolerance

• You are not responding to the treatment
• You have experienced any allergic reaction like rashes and itching
• You have a receiving any concomitant medication and disease
• You develop shortness of breath

Asparaginase 5000IU is used to treat Acute lymphocytic leukemia and Lymphoblastic lymphoma. It is enzymes that alter the natural process which is necessary for a cancer cell to grow which kills and inhibit the growth of cancer cells.

Drug-Drug Interaction

No information is available regarding the use of this medicine. Kindly consult with your doctor if you are receiving any concomitant medications

Drug-Food Interaction

Alcohol

Consuming alcohol may increase the risk of developing liver damage. Kindly inform your doctor if you have experienced upper quadrant pain, abdominal pain, fever, rash, itching, loss of appetite, fatigue, nausea, vomiting, dark urine, and yellow skin.

Drug-Disease Interaction

Coagulation abnormalities

Therapy should be administered with caution in patients with coagulation disorder because the use of this medicine impairs the production of fibrinogen and also decrease the serum level of clotting factors.

Pancreatic dysfunction

The use of this medicine decreases the synthesis of insulin and cause inflammation and cell necrosis so it is contraindicated to use this medicine in a patient who is with the history of pancreatitis

Hepatic dysfunction

Therapy should be administered with caution in patients with hepatic impairment because the use of this medicine may cause an increase in liver enzymes.

Myelosuppression

Therapy should be administered with caution in patients with severe bone marrow suppression because the use of this medicine may cause transient myelosuppression.

Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.

Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).

• Stored at 2-8°C in a refrigerator.
• Do not freeze
• Protect from light and heat.
• Keep away from children and pets. Otherwise, it becomes toxic to them.
• Disposed of properly in a suitable bag.

• Asparaginase 5000IU is an anti-cancer medication, an enzyme
• It is used to treat Acute lymphocytic leukemia and Lymphoblastic lymphoma
• Do not withdraw the medicine without consulting with a doctor
• Kindly use birth control to avoid pregnancy while you are receiving this medicine.
• Kindly consult with your doctor if you have experienced shortness of breath, chest pain, loss of appetite, and dark urine while you are receiving this medicine