Drug Interaction of Lapatem 250mg Tablet 120'S
The use of this medicine is contraindicated because the us of lapatinib will increase the effect of dihydroergotamine by affecting its hepatic and intestinal enzyme metabolism
The use of this medicine is contraindicated because the use of lapatinib will increase the effect of everolimus by P-glycoprotein efflux transporter.
The use of this medicine is contraindicated because the use of lapatinib will increase the effect of pimozide by decreasing its metabolism and it also increase the risk for developing QT interval prolongation
Use alternative drug because the combination of this medicine increase QTc interval
Therapy should be admi9nstered with caution because the use of apalutamide decrease the effect of lapatinib by increasing its metabolism.
Therapy should be administered with caution because the use of cimetidine will decrease the effect of laptinib by increasing its gastric Ph.
Lapatinib 250mg should be taken on an empty stomach one hour before the meal or 2 hours after the meal. You should also avoid grapefruit juice while you are receiving this medicine it may increase the Lapatinib in blood levels.
Therapy should be administered with caution in patients who are having a history of left ventricular function because the use of EGFR inhibitor may cause cardiomyopathy
The use of EGFR inhibitors may cause cutaneous reaction. Kindly wear sunscreen and hats to avoid sun exposure while receiving this therapy
Therapy should be administered with caution in patients with a history of interstitial pneumonitis and pulmonary fibrosis, pulmonary symptoms such as dyspnea, cough and fever because the use of EGFR inhibitors itself associated with pulmonary toxicity.
Patients who are having a history of decreased platelet count and patients on anti-coagulant treatment because the use of this medicine may cause thrombocytopenia
Congestive heart failure
Therapy should be administered with caution in patients who are having a history of previous heart conditions because the use of this medicine may decrease the left ventricular ejection fraction and cause congestive heart failure.