Ledifos Tablet

Brand Name Ledifos Tablet
Salt Composition Ledipasvir (90mg) + Sofosbuvir (400mg)
Strength 400mg + 90mg
Product Form Tablet
Pack 28 Tablet(s) in Bottle
Storage Store at room temperature (10-30°C)
Category Hepatitis
Country of Origin India
Manufacturer Hetero Drugs Limited
Manufacturer/Marketer AddressHetero Drugs Limited,Hetero House, H. No. 8-3-166/7/1, Erragadda, Hyderabad, Andhra Pradesh, 500018 India
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Ledifos Tablet, Sofosbuvir 400mg, Ledipasvir 90mg, Price, Uses, Side Effects - Drugcarts watermark
M.R.P : Rs.25000.00       Price : Rs.18750.00

You Save : Rs.6,250.00    Inclusive of all taxes

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Availability : In Stock


    Medical Description of Ledifos Tablet

    Ledifos Tablet consists of two antiviral combinations. This prescription medicine is used in the treatment of Chronic Hepatitis C virus (HCV) infection. It is used in combination with another medicine, to prevent the spread of HCV throughout the body. It should be taken in the adequate dose and duration. It should not be administered in children under 12 years of age. In case of adults, one tablet is prescribed to be taken every day for about 12 weeks.  It remains for 24hrs in our body. Continue the course of medications until the next visit of doctor.

    This medicine should be used with caution in patients with liver disease, kidney disease and are on dialysis treatment. Consult the doctor if you have any other health issues and taking medicines to treat them.


    Ledifos Tablet Uses

    Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet is used to treat the infection such as Chronic Hepatitis C virus (HCV) infection


    Ledifos Tablet Benefits

    Ledifos Tablet used in the treatment for the following condition like 

    Chronic hepatitis C virus infection:

    It is a chronic liver infection that is caused by the hepatitis C virus. It usually occurs when our body cannot fight against the virus and it is a communicable disease. It occurs when our body fluids get contaminated by the hepatitis C virus. Symptoms include fatigue, bleeding easily, jaundice, dark-coloured urine, itchy skin, weight loss, and hepatic encephalopathy.


    Ledifos Tablet Indication

    Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet should be taken in the prescribed dose and duration. It should be taken with or without food, but take it at the equal time intervals. It is advices not to consume more than the recommended dose. It is important to inform your doctor if you have any health conditions such as liver issues or kidney disease, and are undergoing dialysis not recommended to take this medicine. Inform your doctor while you have any other health issues, taking medicines to treat them.


    Mechanism of action of Ledifos Tablet

    Ledifos inhibits an important viral phosphoprotein, Nonstructural protein 5A (NS5A), which is involved in viral replication, assembly secretion and production of RNA viral infection. Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet itself binds to NS5A (viral phosphoprotein to stop the secretion, replication, assembly and production of RNA viral infection. This improves your health and feels cured of the infection.


    How Ledifos Tablet works

    Ledifos Tablet consists of two antiviral medicines. Ledifos tablet itself binds to NS5A (viral phosphoprotein to stop the secretion, replication, assembly and production of RNA viral infection. This improves your health and feels like cured from the infection.

    Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet is taken as a whole tablet and should not chew or crush the tablet. It should be taken with water. With or without food. Do not take with fresh juice that may reduce the medicine Absorption. As per doctor prescribed take the tablet usual dose, not more than the usual dose that may lead to side effects. Do not take with fatty meals it reduces the effect on our body mechanism. Try to take the medicine in the correct interval of time and do not miss the dose or overdose the tablet that cause major effects.


    Ledifos Tablet Contraindication

    Interaction with medicine

    Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet can cause various side effects on interaction with medicines. Some interactions are

    Carbamazepine

    It is an anticonvulsant used to treat the pain of trigeminal neuralgia. It may induce the hepatic metabolism.

    Rifampicin

    Rifampicin is an antibiotic. This medicine alters the action of rifampicin. Ask your doctor and then take for better quality of life.

    Fosphenytoin

    Fosphenytoin is used in the treatment of epilepsy. It induces the hepatic metabolism.

    Amiodarone

    It is an antiarrhythmic medicine used to treat arrhythmias. This medicine alters the action of amiodarone. Ask your doctor and then take for better quality of life.


    Ledifos Tablet Side Effects

    • Tiredness
    • Headache
    • Blurred vision
    • Dizziness
    • Diarrhea
    • Nausea
    • Vomiting
    • Decreased appetite
    • Fatigue
    • Difficulty in sleeping (Insomnia)
    • Anemia


    FAQs for Ledifos Tablet

    1. Does Ledifos Tablet have habit-forming medicine?

    No Ledifos Tablet is not a habit-forming medicine.

    2. Is it safe to consume alcohol while taking this medicine?

    No. it is not safe with alcohol consumption. Ask your doctor and then take for better quality of life.

    3. How long will Ledifos Tablet sustain in our body?

    It remains for 24hrs in our body

    4. What happens when we take Ledifos Tablet with Amiodarone?

    It is an antiarrhythmic medicine used to treat arrhythmias. This medicine alters the action of amiodarone. Ask your doctor and then take for better quality of life.

    5. Can we take Ledifos Tablet over years of time?

    Consult your doctor for the usage of medicines. Generally, it will give 12 OR 24 weeks duration. However, have to take one tablet each day for 12 weeks; it remains 24 hours in our body.


    Precautions and general warning of Ledifos Tablet

    Alcohol

    No. it is not safe with alcohol consumption. Ask your doctor and then take for better quality of life.

    Driving or operating machinery

    No. It is not safe to drive. It causes dizziness, blurred vision and alters the ability to drive. Ask your doctor and then take for better quality of life.

    Pregnancy

    Yes. It is safe during pregnancy. It doesn’t shows any effects to the foetus. Ask your doctor and then take for better quality of life.

    Breast Feeding

    Yes. It is safe during breast-feeding. It doesn’t shows any effects to the foetus. Ask your doctor and then take for better quality of life.

    Kidney Problem

    It should be used with caution in patients with severe kidney disease. Inform to the doctor, dose adjustment or replacement are suggested. Please consult your doctor if your noticed any side effects. No need of dose adjustment in patients with mild to moderate kidney disease.

    Liver Disease

    Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet is safe to use in patients with liver disease. Ask your doctor and then take for better quality of life.


    How to Take Ledifos Tablet

    Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet is taken orally with or without food.

    It should be taken at a specific time

    Don’t chew or break the tablet.

    Swallow this tablet as whole.

    It must be taken with other antiviral medicines.

    After therapy has been initiated, do not take more or less of this prescribed or stop taking it without your physicians’ approval. Skipping or changing this dose without approval would increase the viral load making the infection more difficult to treat, or worsen side effects. For further queries consult your physician.


    Use of Ledifos Tablet in Adult

    The recommended dose of Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet is taken orally once a day with or without food for 12-24 weeks with or without ribavirin.


    Use of Ledifos Tablet in children

    Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet is not recommended for children below age 3.

     


    Other general warnings

    Should not chew or crush the tablet. It should be taken with water. With or without food. Do not take with fresh juice that may reduce the medicine absorption. As per doctor prescribed take the tablet, not more than the usual dose that may lead to side effects. Do not take with fatty meals it reduces the effect on our body mechanism. Try to take the medicine in the correct interval of time and do not miss the dose or overdose the tablet that cause major effects. Increase in dosage will don't give effective results that may cause double side effects so don't change your dosage as prescribed continue the medicine for better result.


    Talk to your doctor if

    If you have any allergy/ hypersensitivity

    If you have a liver problem

    If you are pregnant or breastfeeding


    General instructions

    Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet consists of two antiviral medicine combination used to treat the Chronic Hepatitis C virus (HCV) infection. It is used in combination with another medicine, to prevent the spread of HCV throughout the body. It should be taken in the adequate dose and duration. It should not be administered in children under 12 years of age.


    Drug Interaction of Ledifos Tablet

    Drug-Drug Interaction

    Increase serum concentration by folic acid, Chondroitin sulfate, Clove oil

    Decrease serum concentration by St. John's Wort

    Metabolism is decreased by Tretinoin

    increase bradycardic activity by Amiodarone and beta blockers

    Drug-Food Interaction

    Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet can be safely taken with any type of food, if doubts arise kindly refer to your physician. It is best to avoid eating grapefruit and drinking grape juice. It generally causes dizziness and instability thus it is advised not to be taken with alcohol.

    Drug-Disease Interaction

    • Liver disorders – used with caution in hepatic impairment and cirrhosis. Consult a physician before use
    • Kidney disorders – used with caution in renal impairment. Consult a physician before use
    • Cardiac disorders – used with caution in bradycardia and arrythmia. Consult a physician before use
    • Respiratory disorders – used with caution in respiratory disorder. Consult a physician before use


    Over Dose

    Take the doses properly as directed by the doctor. Do not be taken as overdose. If you are taken unfortunately, immediately consult the doctor for better quality of life.


    Missed Dose

    Do not skip the dose of Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet as directed by the doctor. If your skipped the dose, take immediately. If your skipped the dose, its nearer to next dose, take properly one dose, do not be taken as double the dose. It leads to overdose, immediately consult the doctor.


    Storage and Disposal

    Should be stored in dry and cool place 10-30 °C

    Keep reach out of children

    Discard the unused and expired tablets properly

    Do not through the tablets in empty ground that may cause harmfulness to environment.

    Do not flush the used tablet strips follow FDA guidelines on how to safe dispose of unused medicine.


    Fast Tag

    Ledifos (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet consists of two antiviral medicine combination. This prescription medicine is used in the treatment of Chronic Hepatitis C virus (HCV) infection. It is used in combination with another medicine, to prevent the spread of HCV throughout the body. It should be taken in the adequate dose and duration. It should not be administered in children under 12 years of age.

    This medicine should be used with caution in patients with liver disease, kidney disease and are on dialysis treatment. Consult the doctor if you have any other health issues and taking medicines to treat them.