Lesovir Tablet
Brand Name | Lesovir Tablet |
Salt Composition |
Ledipasvir (90mg) + Sofosbuvir (400mg) |
Strength | 400mg + 90mg |
Product Form | Tablet |
Pack | 28 Tablet(s) in Bottle |
Storage | Store below 30°C |
Category |
Hepatitis |
SubCategory |
Hepatitis-C |
Country of Origin | India |
Manufacturer |
Zuventus Healthcare Ltd |
Manufacturer/Marketer Address | Zuventus Healthcare Ltd, Office No. 5119, 5th Floor, 'D' Wing, Oberoi Garden Estates, Chandivili, Andheri (E), Mumbai - 400 072. |
You Save : Rs.710.90 Inclusive of all taxes
- Tiredness
- Headache
- Blurred vision
- Dizziness
- Diarrhea
- Nausea
- Vomiting
- Decreased appetite
- Fatigue
- Difficulty in sleeping (Insomnia)
- Anemia
- Liver disorders – used with caution in hepatic impairment and cirrhosis. Consult a physician before use
- Kidney disorders – used with caution in renal impairment. Consult a physician before use
- Cardiac disorders – used with caution in bradycardia and arrythmia. Consult a physician before use
- Respiratory disorders – used with caution in respiratory disorder. Consult a physician before use
Medical Description of Lesovir Tablet
Lesovir Tablet consists of two antiviral combinations. This prescription medicine is used in the treatment of Chronic Hepatitis C virus (HCV) infection. It is used in combination with another medicine, to prevent the spread of HCV throughout the body. It should be taken in the adequate dose and duration. It should not be administered in children under 12 years of age. In case of adults, one tablet is prescribed to be taken every day for about 12 weeks. It remains for 24hrs in our body. Continue the course of medications until the next visit of doctor.
This medicine should be used with caution in patients with liver disease, kidney disease and are on dialysis treatment. Consult the doctor if you have any other health issues and taking medicines to treat them.
Lesovir Tablet Uses
Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet is used to treat the infection such as Chronic Hepatitis C virus (HCV) infection
Lesovir Tablet Benefits
Lesovir Tablet used in the treatment for the following condition like
Chronic hepatitis C virus infection:
It is a chronic liver infection that is caused by the hepatitis C virus. It usually occurs when our body cannot fight against the virus and it is a communicable disease. It occurs when our body fluids get contaminated by the hepatitis C virus. Symptoms include fatigue, bleeding easily, jaundice, dark-coloured urine, itchy skin, weight loss, and hepatic encephalopathy.
Lesovir Tablet Indication
Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet should be taken in the prescribed dose and duration. It should be taken with or without food, but take it at the equal time intervals. It is advices not to consume more than the recommended dose. It is important to inform your doctor if you have any health conditions such as liver issues or kidney disease, and are undergoing dialysis not recommended to take this medicine. Inform your doctor while you have any other health issues, taking medicines to treat them.
Mechanism of action of Lesovir Tablet
Lesovir inhibits an important viral phosphoprotein, Nonstructural protein 5A (NS5A), which is involved in viral replication, assembly secretion and production of RNA viral infection. Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet itself binds to NS5A (viral phosphoprotein to stop the secretion, replication, assembly and production of RNA viral infection. This improves your health and feels cured of the infection.
How Lesovir Tablet works
Lesovir Tablet consists of two antiviral medicines. Lesovir tablet itself binds to NS5A (viral phosphoprotein to stop the secretion, replication, assembly and production of RNA viral infection. This improves your health and feels like cured from the infection.
Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet is taken as a whole tablet and should not chew or crush the tablet. It should be taken with water. With or without food. Do not take with fresh juice that may reduce the medicine Absorption. As per doctor prescribed take the tablet usual dose, not more than the usual dose that may lead to side effects. Do not take with fatty meals it reduces the effect on our body mechanism. Try to take the medicine in the correct interval of time and do not miss the dose or overdose the tablet that cause major effects.
Lesovir Tablet Contraindication
Interaction with medicine
Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet can cause various side effects on interaction with medicines. Some interactions are
Carbamazepine
It is an anticonvulsant used to treat the pain of trigeminal neuralgia. It may induce the hepatic metabolism.
Rifampicin
Rifampicin is an antibiotic. This medicine alters the action of rifampicin. Ask your doctor and then take for better quality of life.
Fosphenytoin
Fosphenytoin is used in the treatment of epilepsy. It induces the hepatic metabolism.
Amiodarone
It is an antiarrhythmic medicine used to treat arrhythmias. This medicine alters the action of amiodarone. Ask your doctor and then take for better quality of life.
Lesovir Tablet Side Effects
FAQs for Lesovir Tablet
1. Does Lesovir Tablet have habit-forming medicine?
No Lesovir Tablet is not a habit-forming medicine.
2. Is it safe to consume alcohol while taking this medicine?
No. it is not safe with alcohol consumption. Ask your doctor and then take for better quality of life.
3. How long will Lesovir Tablet sustain in our body?
It remains for 24hrs in our body
4. What happens when we take Lesovir Tablet with Amiodarone?
It is an antiarrhythmic medicine used to treat arrhythmias. This medicine alters the action of amiodarone. Ask your doctor and then take for better quality of life.
5. Can we take Lesovir Tablet over years of time?
Consult your doctor for the usage of medicines. Generally, it will give 12 OR 24 weeks duration. However, have to take one tablet each day for 12 weeks; it remains 24 hours in our body.
Precautions and general warning of Lesovir Tablet
Alcohol
No. it is not safe with alcohol consumption. Ask your doctor and then take for better quality of life.
Driving or operating machinery
No. It is not safe to drive. It causes dizziness, blurred vision and alters the ability to drive. Ask your doctor and then take for better quality of life.
Pregnancy
Yes. It is safe during pregnancy. It doesn’t shows any effects to the foetus. Ask your doctor and then take for better quality of life.
Breast Feeding
Yes. It is safe during breast-feeding. It doesn’t shows any effects to the foetus. Ask your doctor and then take for better quality of life.
Kidney Problem
It should be used with caution in patients with severe kidney disease. Inform to the doctor, dose adjustment or replacement are suggested. Please consult your doctor if your noticed any side effects. No need of dose adjustment in patients with mild to moderate kidney disease.
Liver Disease
Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet is safe to use in patients with liver disease. Ask your doctor and then take for better quality of life.
How to Take Lesovir Tablet
Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet is taken orally with or without food.
It should be taken at a specific time
Don’t chew or break the tablet.
Swallow this tablet as whole.
It must be taken with other antiviral medicines.
After therapy has been initiated, do not take more or less of this prescribed or stop taking it without your physicians’ approval. Skipping or changing this dose without approval would increase the viral load making the infection more difficult to treat, or worsen side effects. For further queries consult your physician.
Use of Lesovir Tablet in Adult
The recommended dose of Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet is taken orally once a day with or without food for 12-24 weeks with or without ribavirin.
Use of Lesovir Tablet in children
Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet is not recommended for children below age 3.
Other general warnings
Should not chew or crush the tablet. It should be taken with water. With or without food. Do not take with fresh juice that may reduce the medicine absorption. As per doctor prescribed take the tablet, not more than the usual dose that may lead to side effects. Do not take with fatty meals it reduces the effect on our body mechanism. Try to take the medicine in the correct interval of time and do not miss the dose or overdose the tablet that cause major effects. Increase in dosage will don't give effective results that may cause double side effects so don't change your dosage as prescribed continue the medicine for better result.
Talk to your doctor if
If you have any allergy/ hypersensitivity
If you have a liver problem
If you are pregnant or breastfeeding
General instructions
Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet consists of two antiviral medicine combination used to treat the Chronic Hepatitis C virus (HCV) infection. It is used in combination with another medicine, to prevent the spread of HCV throughout the body. It should be taken in the adequate dose and duration. It should not be administered in children under 12 years of age.
Drug Interaction of Lesovir Tablet
Drug-Drug Interaction
Increase serum concentration by folic acid, Chondroitin sulfate, Clove oil
Decrease serum concentration by St. John's Wort
Metabolism is decreased by Tretinoin
increase bradycardic activity by Amiodarone and beta blockers
Drug-Food Interaction
Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet can be safely taken with any type of food, if doubts arise kindly refer to your physician. It is best to avoid eating grapefruit and drinking grape juice. It generally causes dizziness and instability thus it is advised not to be taken with alcohol.
Drug-Disease Interaction
Over Dose
Take the doses properly as directed by the doctor. Do not be taken as overdose. If you are taken unfortunately, immediately consult the doctor for better quality of life.
Missed Dose
Do not skip the dose of Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet as directed by the doctor. If your skipped the dose, take immediately. If your skipped the dose, its nearer to next dose, take properly one dose, do not be taken as double the dose. It leads to overdose, immediately consult the doctor.
Storage and Disposal
Should be stored in dry and cool place 10-30 °C
Keep reach out of children
Discard the unused and expired tablets properly
Do not through the tablets in empty ground that may cause harmfulness to environment.
Do not flush the used tablet strips follow FDA guidelines on how to safe dispose of unused medicine.
Fast Tag
Lesovir (Sofosbuvir (400mg) + Ledipasvir (90mg)) tablet consists of two antiviral medicine combination. This prescription medicine is used in the treatment of Chronic Hepatitis C virus (HCV) infection. It is used in combination with another medicine, to prevent the spread of HCV throughout the body. It should be taken in the adequate dose and duration. It should not be administered in children under 12 years of age.
This medicine should be used with caution in patients with liver disease, kidney disease and are on dialysis treatment. Consult the doctor if you have any other health issues and taking medicines to treat them.