Lilxapla 50mg Injection

Brand Name Lilxapla 50mg Injection
Salt Composition Oxaliplatin (50mg)
Strength 50mg
Product Form Injection
Pack 1 Injection in 1 Vial
Storage Store at room temperature (10-30°C)
Category Anti-Cancer
Country of Origin India
Manufacturer Eli Lilly and Company India Pvt Ltd
Manufacturer/Marketer AddressEli Lilly and Company India Pvt Ltd, Plot# 92, Sector 32, Institutional Area, Gurgaon-122001, HARYANA, INDIA
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M.R.P : Rs.3068.00       Price : Rs.2454.40

You Save : Rs.613.60    Inclusive of all taxes

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1 Injection in 1 Vial

Availability : In Stock


    Medical Description of Lilxapla 50mg Injection

    Lilxapla 50mg Injection contains Oxaliplatin 50mg used to treat cancer of the colon and rectum. It works by inhibiting the growth and multiplication of cancer cells by damaging the DNA and RNA of cancer cells. It is not recommended in children and adolescents who are below 18 years old.


    Lilxapla 50mg Injection Uses

    It is used in the treatment of the following conditions as Colorectal cancer


    Lilxapla 50mg Injection Benefits

    Colorectal cancer

    It is also called colon cancer. It is a type of cancer that starts from the large intestine and it usually affects older adults. It occurs when there is a change in the DNA of the normal cells. Symptoms include a change in bowel movement, rectal bleeding, fatigue, and weight loss. This medicine helps to inhibit the multiplication of cancer cells.


    Lilxapla 50mg Injection Indication

    The Lilxapla 50mg Injection is prescribed in the following indications as colorectal cancer. It is used as an orphan drug in the case of

    • Non-Hodgkin Lymphoma
    • Chronic Lymphocytic Leukemia
    • Esophageal Cancer
    • Neoplasm of Stomach
    • Neuroendocrine Tumor
    • Testicular Cancer
    • Ovarian Cancer
    • Pancreatic Adenocarcinoma
    • Cholangiocarcinoma


    Mechanism of action of Lilxapla 50mg Injection

    Lilxapla 50mg Injection contains Oxaliplatin 50mg is an anti-cancer medication, an alkylating agent produces its action by causing intra- and inter-strand crosslinks between DNA bases causing a break in DNA strand thus apoptosis is induced resulting in cell death of abnormal DNA containing cancer cells.

     


    How Lilxapla 50mg Injection works

    Lilxapla 50mg Injection contains Oxaliplatin 50mg is an anti-cancer medication, an alkylating agent produces its action by causing fragmentation in the DNA base pair which leads to inhibition of further synthesis and transcription of DNA. Thus it inhibits proliferation and induces apoptosis (cell death) of these abnormal cancer cells.


    Lilxapla 50mg Injection Contraindication

    • Do not take this medicine if you are allergic to Oxaliplatin
    • It is contraindicated to use this medicine in patients who are pregnant, with myelosuppression, peripheral neuropathy, and chronic kidney disease


    Lilxapla 50mg Injection Side Effects

    • Anemia
    • Fatigue
    • Diarrhea
    • Abdominal pain
    • Constipation
    • Fever
    • Leukopenia
    • Cough
    • Edema
    • Pulmonary fibrosis
    • Thrombocytopenia
    • Leukopenia


    FAQs for Lilxapla 50mg Injection

    • Is Lilxapla 50mg Injection safe?

    Yes, the use of this medicine is considered safe if you have taken the medicine as per the dose and duration advised by the doctor.

    • I am experiencing nausea and fatigue. Is this due to Lilxapla 50mg Injection?

    Yes, the common side effect of this medicine is nausea and fatigue so it is better to eat more frequent meals to decrease nausea and also avoid foods that are salty, spicy, fatty. Drink plenty of rest and do light exercise to keep yourself active

    • Does Lilxapla 50mg Injection cause hair loss?

    Yes, one of the common side effects of this medicine is hair loss. This will get treated once you stop the treatment.


    Precautions and general warning of Lilxapla 50mg Injection

    Alcohol

    It is not clear that consuming alcohol is safe while you are receiving this medicine. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive because Oxaliplatin will increase the risk for developing dizziness, nausea, and vomiting. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor

    Kidney Problem

    Therapy should be administered with caution in patients who are having a renal impairment. Adjust the dose as per the requirement. Kindly consult with your doctor.

    Liver Disease

    Therapy should be administered with caution in patients who are having hepatic impairment. Adjust the dose as per the requirement. Kindly consult with your doctor.

     


    How to Take Lilxapla 50mg Injection

    Lilxapla 50mg Injection comes in a liquid solution as an intravenous. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Lilxapla 50mg Injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.


    Use of Lilxapla 50mg Injection in children

    It is considered unsafe to use this medicine in children who are below 18 years old. Kindly consult with your doctor.


    Use of Lilxapla 50mg Injection in Elderly Patients

    Lilxapla 50mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • Therapy should be administered with caution in patients with renal impairment and elderly patients with neuropathy.
    • Kindly avoid taking this medicine with aluminum needles
    • Avoid breathing cold air
    • The use of this medicine can cause fetal harm, so it is advised to females to use effective contraception to avoid pregnancy
    • The use of this medicine along with fluorouracil may increase the gastrointestinal effects
    • Pulmonary fibrosis and Cardiovascular toxicity was reported
    • The use of this medicine may cause reversible posterior leukoencephalopathy syndrome and rhabdomyolysis


    Talk to your doctor if

    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have a receiving any concomitant medication and disease
    • You develop shortness of breath


    General instructions

    Oxaliplatin 50mg is used to treat cancer of the colon and rectum. It produces its action by causing fragmentation in the DNA base pair which leads to inhibition of further synthesis and transcription of DNA. Thus it inhibits proliferation and induces apoptosis (cell death) of these abnormal cancer cells.


    Drug Interaction of Lilxapla 50mg Injection

    Drug-Drug Interaction

    Cidofovir

    Use alternative drugs because the combination of this medicine increases the nephrotoxicity and ototoxicity

    Fingolimod

    Use alternative drugs because the use of oxaliplatin increases the effect of fingolimod by immunosuppressive effect and it also increases the risk for developing an infection

    Chlorambucil

    Therapy should be administered with caution because the combination of this medicine either increases the toxicity of the other by pharmacodynamic synergism

    Ciprofloxacin

    Therapy should be administered with caution because the use of Oxaliplatin will increase the effect of ciprofloxacin by prolonging the QT interval

    Fosphenytoin

    Therapy should be administered with caution because the use of oxaliplatin decreases the effect of fosphenytoin by increasing its metabolism.

    Drug-Food Interaction

    No data is available kindly consult with your doctor.

    Drug-Disease Interaction

    Arrhythmia

    Therapy should be administered with caution in patients with congestive heart failure, bradyarrhythmia and electrolyte abnormalities because the use of this medicine is associated with QT prolongation and ventricular arrhythmias

    Pulmonary toxicity

    Therapy should be administered with caution in patients with a history of interstitial pneumonitis and pulmonary fibrosis because the use of this medicine associated with pulmonary toxicity

    Neutropenia

    Therapy should be administered with caution in patients with neutropenia because the use of this medicine is associated with sepsis, neutropenic sepsis, and septic shock

    Renal impairment

    Therapy should be administered with caution in patients with renal impairment because the route of elimination is from renal so it is advised to reduce the dose in patients with severe renal impairment

    Thrombocytopenia

    Therapy should be administered with caution in patients with bone marrow suppression because the use of this medicine can cause thrombocytopenia


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 25°C at room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • Oxaliplatin 50mg is an anti-cancer medication, an alkylating agent
    • It is used to treat colorectal cancer
    • Do not withdraw the medicine without consulting with a doctor
    • Kindly consult with your doctor if you have experienced shortness of breath, chest pain, loss of appetite, and dark urine while you are receiving this medicine