Brand Name Limus 1mg Tablet
Salt Composition Sirolimus (1mg)
Strength 1mg
Product Form Tablet
Pack 10 Tablet(s) in Strip
Storage Store at room temperature (10-30°C)
Category Immunosuppressant
Country of Origin India
Manufacturer Claris Lifesciences Ltd
Manufacturer/Marketer AddressClaris Lifesciences Ltd,Corporate Tower, Parimal Railway Crossing, Ahmedabad, GUJARAT, 380006 India
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M.R.P : Rs.1365.00       Price : Rs.1092.00

You Save : Rs.273.00    Inclusive of all taxes

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10 Tablet(s) in Strip

Availability : In Stock

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    Medical Description of Limus 1mg Tablet

    Limus 1mg tablet contains Sirolimus 1mg an Immunosuppressant used to prevent organ rejection in patients who have undergone kidney transplants. It produces its action by reducing the activity of our immune system so that it will not attack the transplanted organs


    Limus 1mg Tablet Uses

    Limus 1mg tablet is used to prevent organ rejection in the kidney


    Limus 1mg Tablet Benefits

    Organ rejection:

    It occurs when the immune system attacks the organ donated and started to destroy the transplanted organs. It is caused by antibodies that act against the organ and it begins within minutes to hours as soon as organ transplantation.


    Limus 1mg Tablet Indication

    The Limus 1mg tablet is prescribed for the following indications to prevent organ rejection


    Mechanism of action of Limus 1mg Tablet

    Limus 1mg tablet contains Sirolimus 1mg is an Immunosuppressant that produces its action by decreasing your body's immune response following an organ transplant like liver, kidney, and heart. The use of this medicine helps your body to accept the new organ.


    How Limus 1mg Tablet works

    Limus 1mg tablet contains Sirolimus 1mg is an Immunosuppressant that produces its action by decreasing your body's immune response following an organ transplant like liver, kidney, and heart. The use of this medicine helps your body to accept the new organ.


    Limus 1mg Tablet Contraindication

    • Do not take this medicine if you are allergic to Sirolimus
    • It is contraindicated to use this medicine along with live vaccines


    Limus 1mg Tablet Side Effects

    • Constipation
    • Rash
    • Thrombocytopenia
    • Abdominal pain
    • Diarrhea
    • Urinary tract infection
    • Anemia
    • Edema
    • Infection


    FAQs for Limus 1mg Tablet

    • What should I be aware of before I start taking the Limus 1mg tablet?

    This medicine decreases the immune system so it increases the risk of infection. Kindly consult with your doctor before initiating the medicine.

    • Which vaccines should not be taken while taking Limus 1mg tablet?

    You should avoid taking any live vaccines while you are receiving this medicine. Vaccines include measles, mumps, rubella, BCG, yellow fever, chickenpox, and typhoid. 

    • Does Limus 1mg tablet have an abuse potential?

    No, the use of this medicine does not have abuse potential, it does not come under a controlled substances


    Precautions and general warning of Limus 1mg Tablet

    Alcohol

    It is not clear whether it is safe to consume alcohol while you are receiving this medicine. Kindly consult with your doctor

    Driving or operating machinery

    It is considered safe to drive while you are using this medicine. Kindly consult with the doctor

    Pregnancy

    It is considered unsafe during pregnancy it may produce harmful effects on the fetus. Kindly consult with your doctor.

    Breast Feeding

    It is considered unsafe to use this medicine during breastfeeding it may excrete via breast milk. Kindly consult with your doctor.

    Kidney Problem

    It is considered safe to use this medicine in patients with renal impairment. Kindly consult with your doctor.

    Liver Disease

    This medicine should be used with caution in patients with severe liver impairment. The use of this medicine required dose modification. Kindly consult with your doctor.


    How to Take Limus 1mg Tablet

    The tablet is taken orally with or without food but it is better to take this medicine at a fixed time. You should not chew, cut or crush the tablet. Take this medicine as per the dose and duration advised by your doctor. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Limus 1mg Tablet in Adult

    It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.


    Use of Limus 1mg Tablet in children

    Limus 1mg tablet is considered safe to use this medicine in children. Kindly consult with your doctor.


    Use of Limus 1mg Tablet in Elderly Patients

    Limus 1mg tablet should be used with caution in patients in an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The use of this medicine may cause a hypersensitivity reaction and it also increases the risk of infection and lymphoma
    • The patients who are receiving immunosuppressants are at increased risk of developing infections
    • The use of this medicine may cause hypertension, mild-severe hyperkalemia, myocardial hypertrophy, QT prolongation, gastrointestinal perforation, and posterior reversible encephalopathy


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reactions like rashes and itching
    • You are suffering from anemia
    • You have watery diarrhea, stomach pain, and fever


    General instructions

    Sirolimus 1mg an Immunosuppressant used to prevent organ rejection in patients who have undergone kidney transplants. It produces its action by reducing the activity of our immune system so that it will not attack the transplanted organs


    Drug Interaction of Limus 1mg Tablet

    Drug-Drug Interaction

    Anthrax vaccine + Sirolimus

    Sirolimus decreases the effect of the anthrax vaccine by pharmacodynamic antagonism. Immunosuppressants increase the risk of infection in combination with live vaccines

    Atazanavir + Sirolimus

    Atazanavir will increase the effect of sirolimus by affecting hepatic or intestinal enzymes. The use of this drug is contraindicated

    Conivaptan + Sirolimus

    Conivaptan will increase the effect of sirolimus by affecting hepatic or intestinal enzymes. The use of this drug is contraindicated

    Fluconazole + Sirolimus

    Fluconazole will increase the effect of sirolimus by affecting hepatic or intestinal enzymes. The use of this drug is contraindicated

    Adalimumab + Sirolimus

    The combination of this drug increases the effect of immunosuppressants and increases the risk of infection. Use alternative drug

    Anakinra + Sirolimus

    The combination of this drug increases the effect of immunosuppressants and increases the risk of infection. Use alternative drug

    Drug-Food Interaction

    The use of grapefruit can increase the effect of sirolimus and increase the side effect on the kidney, liver, and nervous systems. Consult with your doctor if you have the following symptoms such as fever, rash, nausea, vomiting, dark urine, and jaundice.

    Drug-Disease Interaction

    Infections

    Patients who are receiving immunosuppressants are at higher risk of developing bacterial, viral, fungal, and protozoal diseases. Therapy with immunosuppressants should be administered with caution in diseased patients.

    Progressive multifocal leukoencephalopathy

    The use of immunosuppressants may increase the risk of progressive multifocal leukoencephalopathy. Closely monitor the patient new symptoms of PML.

    Angioedema

    Patients who are taking sirolimus along with ACE inhibitors may have an increased risk of developing angioedema. Closely monitor the patient.

    Hyperlipidemia

    The use of sirolimus may increase serum cholesterol and triglycerides levels. Therapy should be administered with caution to the patients who are receiving both sirolimus and hyperlipidemic agent. Closely monitor the patient cholesterol and triglycerides level

    Liver diseases:

    Sirolimus metabolized in the intestinal wall and liver undergoes counter-transport from enterocytes of the small intestine into the gut lumen. Therapy should be administered with caution to the patient with hepatic impairment.

    Liver transplantation:

    The use of sirolimus is contraindicated to the patient who has undergone liver transplantation because there is no information regarding its safety and efficacy.

    Lung dysfunction:

    Patients who are receiving sirolimus are more prone to develop interstitial lung diseases like pneumonitis, bronchiolitis, and pulmonary fibrosis. Discontinue the drug if the patient develops interstitial lung diseases.

    Lung transplant:

    The use of sirolimus is contraindicated to the patient who has undergone lung transplantation because there is no information regarding its safety and efficacy.

    Renal dysfunction:

    Patients who are receiving both sirolimus and cyclosporine for a long duration are more prone to develop impaired renal function. Closely monitor the patient's renal function


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose on this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • Limus 1mg tablet contains Sirolimus 1mg an Immunosuppressant used to prevent organ rejection in patients who have undergone kidney transplants.
    • It produces its action by reducing the activity of our immune system so that it will not attack the transplanted organs
    • Kindly avoid consuming grapefruit while you are receiving this medicine
    • Kindly monitor your kidney and liver function while you are receiving this medicine
    • Without consulting with a doctor do not take this medicine
    • Inform your doctor if you have experienced bruising, bleeding, sore throat, mouth ulcers, fever and illness