Loxitin P 100mg/100mg Suspension

Loxitin P 100mg/100mg Suspension contains Norfloxacin 100mg and Tinidazole 100mg used to treat bacterial and parasitic infections such as Diarrhoea and Dysentery. Mainly this bacterial infection targets the urinary tract, nose, throat, skin and soft tissues, and lungs. Norfloxacin 100mg is an antibiotic that helps to inhibit the growth of infection. Tinidazole 100mg is antihelmintic which kills the parasites and anaerobic bacteria. This combination of medicine helps to kill microorganisms. This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial infections.

It is used in the treatment of the following conditions as bacterial and parasitic infections such as Diarrhoea and Dysentery

Bacterial infections

Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

Diarrhea

Infection to the digestive tract leads to increased frequency of bowel movements or loose watery bowel movements caused by bacteria called diarrhea. It leads to worsening the patient’s health condition. This medicine is used to treat this bacterial infection.

Dysentery

It is also called infectious diarrhea. Inflammation of the gut (intestine) leads to bloody stools or watery stools. It is most often caused by shigella bacteria (shigellosis) or an amoeba (parasite), spreading through contaminated food or water. This medicine is used to treat this bacterial infection.

The Loxitin P 100mg/100mg Suspension is prescribed in the following indications as bacterial, parasitic infections, Diarrhoea and Dysentery

Loxitin P 100mg/100mg Suspension contains Norfloxacin 100mg and Tinidazole 100mg is a combination of two medicines. Norfloxacin 100mg is a quinolone antibiotic that produces its action by inhibiting the activity of a bacterial enzyme called DNA gyrase and preventing the bacterial cell from reproduction and repairing themselves and killing the bacteria which is responsible for the infection.

Tinidazole 100mg is antihelmintic that produces its action by damaging their DNA and killing the parasites and anaerobic bacteria which is responsible for infections.

Loxitin P 100mg/100mg Suspension contains Norfloxacin 100mg and Tinidazole 100mg is a combination of two medicines. Norfloxacin 100mg is a quinolone antibiotic that produces its action by inhibiting the activity of a bacterial enzyme called DNA gyrase and preventing the bacterial cell from reproduction and repairing themselves and killing the bacteria which is responsible for the infection.

Tinidazole 100mg is antihelmintic that produces its action by damaging their DNA and killing the parasites and anaerobic bacteria which is responsible for infections.

• Do not take this medicine if you are allergic to Norfloxacin, and Tinidazole
• It is contraindicated to use the medicine that may prolong the QT interval
• It is contraindicated to use this medicine if you have a history of tendon infection or tendon rupture, nerve-related problems, myasthenia gravis, and blood disorders

• Photosensitivity
• Tendon rupture
• Thrombocythemia
• Platelets increased
• Neutropenia
• Dizziness
• Increased transaminases
• Headache
• Constipation
• Dyspepsia
• Dizziness

• Can the use of Loxitin P 100mg/100mg Suspension cause a metallic taste?

Yes, the use of this medicine may cause a temporary metallic taste and it can be treated by chewing sugar-free gum or mints and by keeping you hydrated.

• Can I take a higher them the recommended dose of this medicine to get quick relief?

No, you should not take higher than the recommended dose it may cause unwanted effects. Kindly consult with your doctor if your symptoms persist even after you complete the course of treatment

• Can a diabetic patient take a Loxitin P 100mg/100mg Suspension?

The use of this medicine may decrease the blood glucose level. So kindly consult with your doctor before taking the medicine

Alcohol

The use of alcohol may cause flushing, increased heartbeat, nausea, thirst, chest pain, and low blood pressure while you are receiving this medication. Kindly consult with your doctor

Driving or operating machinery

It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

Pregnancy

The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects on the fetus. Kindly consult with your doctor

Breast Feeding

The use of this medicine is considered unsafe during breastfeeding because it may excrete via breast milk. Kindly consult with your doctor

Kidney Problem

The medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

Liver Disease

It is considered safe to use this medicine in patients with hepatic impairment and it does not require dose modification. Kindly consult with your doctor.

Loxitin P 100mg/100mg Suspension is taken orally with or without food. You can measure the dose with the help of a measuring cup and shake well before using this suspension. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.

It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.

It is considered unsafe to use this medicine in children who are below 3 years. Kindly consult with your doctor.

Loxitin P 100mg/100mg Suspension should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.

• Therapy should be administered with caution in patients who are having a history of blood dyscrasias and hepatic impairment
• Kindly avoid using this medicine if you have peripheral neuropathy and seizure
• The use of this medicine may increase the risk for developing bacterial overgrowth with long term treatment

              Tendinitis and Tendon rupture (Muscle damage)

• This medicine causes tendinitis and tendon rupture, which mainly affects your shoulder, hands, ankles, or other joint parts of your body. And muscle damage also occurs usually on the tendons surrounding the muscles. It may experience pain, numbness, or tingling sensations in your muscles. It should be a risk in patients of more than 60 years of age or undergone a transplant of kidney, heart, or lung. If necessary, then needs dose adjustment or replacement

             Diarrhea

• This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. It leads to worsening the patient’s health condition. Better to take probiotics with this medicine to avoid diarrhea.

               Antibiotic resistance

• Finish the complete course of antibiotics even if you feel better. Otherwise, it will lead to Antibiotic resistance (the bacteria may be resistant to antibiotics)

• You have a history of gastrointestinal disease
• You are not responding to the treatment
• You have experienced any allergic reaction like rashes and itching
• You have a history of joint issues
• You have a Glucose-6 phosphate dehydrogenase

• Norfloxacin 100mg is a quinolone antibiotic that produces its action by inhibiting the activity of a bacterial enzyme called DNA gyrase and preventing the bacterial cell from reproduction and repairing themselves and killing the bacteria which is responsible for the infection.
• Tinidazole 100mg is antihelmintic that produces its action by damaging their DNA and killing the parasites and anaerobic bacteria which is responsible for infections.

Drug-Drug Interaction

BCG vaccine live

The use of this drug is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism

Aluminum hydroxide

Use alternative drugs because the use of aluminum hydroxide decreases the effect of norfloxacin by inhibiting the GI absorption

Escitalopram

Therapy should be administered with caution because the use of escitalopram increase the toxicity of norfloxacin by QTc interval

Estradiol

Therapy should be administered with caution because the use of norfloxacin decreases the effect of estradiol by altering the intestinal flora and it also lowers the risk of contraceptive failure.

Anti-diabetic drug

Therapy should be administered with caution because the use of norfloxacin increases the effect of glimepiride by pharmacodynamic synergism.

Haloperidol

It should be administered with caution because the combination of this medicine increases the QTc interval.

Dronabinol

The use of this drug is contraindicated because the use of tinidazole increases the toxicity of dronabinol by inhibiting aldehyde dehydrogenase

Ketoconazole

Use alternative drugs because the use of ketoconazole increases the effect of tinidazole by affecting its hepatic or intestinal metabolism

Drug-Food Interaction

No interaction was found while using this medicine

Drug-Disease Interaction

Central nervous system disorders

Using this medicine is needs caution in patients with seizures, other central nervous system abnormalities, or fits. It causes hallucinations, anxiety, confusion, and restlessness, etc. Inform the doctor, then will do dose adjustment or replacement is needed. If necessary to take this medicine with seizure medications.

Colitis

This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This drug should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient’s health condition.

QT prolongation

This drug should be used with caution in patients with heart-related problems such as irregular heart rate, in which this drug alters the heart rate.

Kidney diseases

It should be used with caution in a patient with renal impairment or kidney disease. Then it leads to the risk of kidney damage. Based on the patient clinical condition, adjust the dose accordingly.

Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.

Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).

• Stored at 10-30°C room temperature.
• Protect from light and heat.
• Keep away from children and pets. Otherwise, it becomes toxic to them.
• Disposed of properly in a suitable bag.

• Loxitin P 100mg/100mg Suspension contains Norfloxacin 100mg and Tinidazole 100mg used to treat bacterial and parasitic infections such as Diarrhoea and Dysentery. Mainly this bacterial infection targets the urinary tract, nose, throat, skin and soft tissues, and lungs.
• Norfloxacin 100mg is a quinolone antibiotic used to treat bacterial infection by preventing bacteria reproduction and repairing themselves. Tinidazole 100mg is an antihelmintic used to kill other infectious microorganisms in addition to bacteria by binding their DNA. This drug combination prevents bacterial infections effectively.
• This medicine is not used for common flu and cold symptoms. And not treat viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial and parasitic infections.
• This medicine is contraindicated to allergic symptoms such as skin rash, itching, swelling, and breathing difficulties.