Macromycin Tablet

Brand Name Macromycin Tablet
Salt Composition Spiramycin (3 Million IU)
Strength 3 Million IU
Product Form Tablet
Pack 10 Tablet(s) in Strip
Storage Store at room temperature (10-30°C)
Category Antibiotic
Country of Origin India
Manufacturer Macleods Pharmaceuticals Pvt Ltd
Manufacturer/Marketer AddressMacleods Pharmaceuticals Pvt Ltd,Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
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M.R.P : Rs.499.00    

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10 Tablet(s) in Strip

Availability : In Stock

  Online Payment Only



    Medical Description of Macromycin Tablet

    Macromycin Tablet contain Spiramycin 3 Million IU used to treat bacterial and parasitic infections such as severe bacterial infections as Bacterial infections, Toxoplasmosis during pregnancy, and Gonorrhoea. Spiramycin is an antibiotic used to treat a parasitic infection called Toxoplasmosis in pregnant women and it also helps to reduce the risk of transmission of toxoplasma infection from the mother to the fetus and it is also used to treat gonorrhea in patients who are allergic to penicillin. Mainly this bacterial infection targets the respiratory tract, buccal cavity, skin and skin structures, and sexually transmitted infections. This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial and parasitic infections.


    Macromycin Tablet Uses

    It is used in the treatment of the following conditions as Bacterial infections, Toxoplasmosis during pregnancy, and Gonorrhoea


    Macromycin Tablet Benefits

    Bacterial infections

    Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

    Toxoplasmosis during pregnancy

    It is caused by the Toxoplasma gondi parasite. It usually occurs by eating undercooked contaminated meat, infected cat feces, or mother-to-child transmission during pregnancy. It may lead to miscarriage, stillbirth, and preterm birth. This medicine helps pregnant women to prevent toxoplasma infections (chances of transmission of infection to the fetus). Used as a second-line treatment drug for toxoplasmosis during pregnancy.

    Gonorrhea

    It is a sexually transmitted infection that infects both men and women caused by Neisseria gonorrhea bacteria. This medicine is used to treat this bacterial infection who are allergic to penicillin treatment.


    Macromycin Tablet Indication

    The Macromycin Tablet is prescribed in the following indications as Bacterial infections, Toxoplasmosis during pregnancy, and Gonorrhoea


    Mechanism of action of Macromycin Tablet

    Macromycin Tablet contains Spiramycin 3 Million IU is a macrolide antibiotic that produces its action by preventing the protein synthesis which is essential for the bacteria to function and it also prevents the infection from spreading.


    How Macromycin Tablet works

    Macromycin Tablet contains Spiramycin 3 Million IU is a macrolide antibiotic that produces its action by preventing the protein synthesis which is essential for the bacteria to function and it also prevents the infection from spreading.


    Macromycin Tablet Contraindication

    • Do not take this medicine if you are allergic to Spiramycin
    • It is contraindicated to use this medicine in patients who are having Bacterial meningitis and Toxoplasma encephalitis
    • Kindly avoid taking this medicine if you have a history of cholestatic jaundice or any hepatic dysfunction


    Macromycin Tablet Side Effects

    • Diarrhea
    • Abnormal liver function
    • Skin rash
    • Swelling of eyelids, face, lips, tongue
    • Peeling and skin blisters
    • Vasculitis
    • Burning and stinging
    • Irregular heart rate
    • Abnormal blood counts
    • Hypotension


    FAQs for Macromycin Tablet

    • Can the use of Macromycin Tablet cause infertility?

    There is no scientific information that the use of this medicine will cause infertility in both male and female

    • How long should I take the Macromycin Tablet?

    Normally the duration of this medicine depends upon the severity of the disease. You should take this according to your doctor advice

    • Is the Macromycin Tablet is effective?

    Yes, it is considered effective when you have taken the medication as per the dose and duration advised by the doctor. If you stop the medicine without completing the course of treatment it may worsen the conditions


    Precautions and general warning of Macromycin Tablet

    Alcohol

    The use of alcohol does not produce harmful effects while you are receiving this treatment. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered safe to drive while you are receiving this medicine it does not affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered safe during pregnancy because it does not produce any harmful effects on the fetus. Kindly consult with your doctor

    Breast Feeding

    Limited information is available regarding the use of this medicine during breastfeeding. Kindly consult with your doctor

    Kidney Problem

    It is considered safe to use this medicine in patients who are having kidney diseases and it does not require dose modification. Kindly consult with your doctor.

    Liver Disease

    Limited information is available regarding the use of this medicine to patients who are having hepatic impairment. Kindly consult with your doctor:


    How to Take Macromycin Tablet

    Macromycin Tablet is taken orally with or without food. You should not chew, cut or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Macromycin Tablet in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.


    Use of Macromycin Tablet in children

    Macromycin Tablet is considered unsafe to use this medicine in children who are below 3 months old. Kindly consult with your doctor.


    Use of Macromycin Tablet in Elderly Patients

    Macromycin Tablet should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • Therapy should be administered with caution because it is associated with QT interval prolongation and arrhythmias
    • The use of this medicine may cause hepatic dysfunction like increased liver enzyme activity, hepatocellular and cholestatic hepatitis with or without jaundice.
    • Kindly discontinue the treatment if you have noticed dark urine, tender abdomen, jaundice, anorexia, and pruritus
    • The use of this medicine may cause Clostridium difficile associated diarrhea


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching


    General instructions

    Macromycin Tablet contain Spiramycin 3 Million IU used to treat bacterial and parasitic infections such as severe bacterial infections as Bacterial infections, Toxoplasmosis during pregnancy, and Gonorrhoea. Spiramycin 3 Million IU is an antibiotic used to treat a parasitic infection called Toxoplasmosis in pregnant women and it also helps to reduce the risk of transmission of toxoplasma infection from the mother to the fetus and it is also used to treat gonorrhea in patients who are allergic to penicillin. Mainly this bacterial infection targets the respiratory tract, buccal cavity, skin and skin structures, and sexually transmitted infections.


    Drug Interaction of Macromycin Tablet

    Drug-Drug Interaction

    BCG vaccine live

    The use of this drug is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism

    Cabergoline

    The use of this medicine is contraindicated because the use of Spiramycin may increase the effect of cabergoline by decreasing its metabolism.

    Chloroquine

    The use of this medicine is contraindicated because the use of chloroquine increases the toxicity of Spiramycin by QTc interval

    Lovastatin

    The use of Spiramycin will increase the effect of lovastatin by P-glycoprotein efflux transporter

    Aripiprazole

    Use alternative drugs because the use of Spiramycin will increase the effect of aripiprazole by affecting hepatic or intestinal enzyme metabolism

    Digoxin

    Therapy should be administered with caution because the use of Spiramycin will increase the effect of digoxin by P-glycoprotein efflux transporter

    Drug-Food Interaction

    The use of grape juice along with Spiramycin may affect gastrointestinal absorption and it also inhibits the metabolism of Spiroomycin.

    Drug-Disease Interaction

    Gastrointestinal diseases

    It should be used with caution in patients with gastrointestinal diseases, particularly colitis (infection to the inner lining of the colon). It will lead to worsening the patient’s health condition. If you are noticed severe diarrhea, abdominal pain, blood in stools, etc. immediately inform the doctor. Based on the patient clinical condition, dose adjustment is needed.

    QT Prolongation

    Therapy should be administered with caution because the use of Spiramycin may cause prolonged cardiac repolarization, QT interval in patients who are having a history of congenital long QT syndrome, bradyarrhythmias, proarrhythmic conditions such as uncorrected hypokalemia, hypomagnesemia

    Renal dysfunction:

    Spiramycin should be administered with caution because the use of this medicine gets eliminated by the kidney. It is not necessary to adjust the dose in patients with mild to moderate renal impairment.

    Electrolyte imbalance

    It should be used with caution in patients with electrolyte imbalance or fluid retention. It leads to worsening patient health conditions. Based on the patient clinical condition, dose adjustment or replacement is needed.

    Cross-resistance

    This medicine doesn’t show effectiveness in the treatment of infections where resistance developed by causative bacteria due to the usage of erythromycin. It is called cross-resistance. It leads to worsening the patient health condition

    Myasthenia gravis

    Therapy should be administered with caution in patients with a history of myasthenia gravis because the use of macrolide antibiotics may worsen the conditions


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    Macromycin Tablet contain Spiramycin 3 Million IU used to treat bacterial and parasitic infections such as severe bacterial infections as Bacterial infections, Toxoplasmosis during pregnancy, and Gonorrhoea. Spiramycin 3 Million IU is a macrolide antibiotic used to treat bacterial infections. It eradicates bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.

    This medicine is not used for common flu and cold symptoms. And not treat viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial and parasitic infections.

    This medicine is contraindicated to allergic symptoms such as skin rash, itching, swelling and breathing difficulties, bacterial meningitis, and toxoplasma encephalitis.