Mahacloxin 250 mg/250 mg Capsule

Mahacloxin 250 mg/250 mg Capsule contains Ampicillin 250mg and Dicloxacillin 250mg used to treat bacterial infections such as urinary tract infections, endocarditis, genitourinary tract infections, Gonorrhea, respiratory tract infection, bacterial meningitis in children. Mainly this medicine targets infections of the lungs, throat, airways, skin and soft tissue, bone, ear, nose, heart, and blood. Ampicillin is a penicillin derivative that is effective against both gram-negative and gram-positive bacteria and helps to kill the bacteria. Dicloxacillin is an antibiotic used to treat the bacterial infection which mainly targets the lungs, ear, nasal sinus, urinary tract, and skin infections. The combination of this medicine helps to fight against the infection that is caused by bacteria. This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial infections.

It is used in the treatment of the following conditions as Bacterial infections, urinary tract infections, endocarditis, genitourinary tract infections, Gonorrhea, respiratory tract infection, bacterial meningitis.

Bacterial infections:

Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

Urinary tract infection

It is a type of infection that affects the urethra, kidneys, and bladder. It is caused by Escherichia coli (E.coli). Symptoms include abdominal pain, frequent urination, dysuria, blood in urine, foul-smell while urinating

Acute bronchitis

It is a viral infection that causes inflammation in the bronchial tubes. It is mostly caused by rhinovirus, adenovirus, influenza A and B, and parainfluenza virus. Symptoms include cough, fatigue, breathing difficulty, fever and chills, and chest discomfort.

Lower respiratory tract infections:

Infection in the lungs especially in the lower airways Common infections are Bronchiolitis and Pneumonia which are caused by Streptococcus pneumonia. Symptoms include runny nose, dry cough, sore throat, low-grade fever, and headache.

Acute sinusitis

It is also called acute rhinosinusitis.  It is an inflammation inside your nose which is called sinusitis. It is usually caused by the common cold, or by any viral or bacterial infection. Symptoms include runny nose, postnasal drainage, congestion, swelling around your eyes, ear pressure, headache, cough, bad breath, fatigue, and fever.

Ear, Nose and Throat infection:

Ear, Nose, and Throat infection includes Tonsillitis, Ear infections, Sinus infections.

Tonsillitis:

Inflammation of tonsils is called tonsillitis which causes server throat pain and is caused by Streptococcus pyogenic. Symptoms include inflamed tonsils, sore throat, difficulty in swallowing, bad breath, headache, and inflamed lymph nodes

Ear infection:

It usually occurs when the bacterial or viral infection affects your middle ears. It is caused by colds, sinus infections, smoking, allergies, and inflamed adenosis. Symptoms include pain, hearing loss, pus-like drainage.

Genitourinary tract infection

It is a type of infection that affects the urethra, kidneys, and bladder. It is caused by Escherichia coli (E.coli). Symptoms include abdominal pain, frequent urination, dysuria, blood in urine, foul-smell while urinating

Skin infection

It is usually caused by bacteria, fungi, viruses, and parasites. Common skin infection includes cellulitis, impetigo. Symptoms include red skin, blisters, swelling, pain, red spots, and tenderness

Bacterial meningitis

Infection and inflammation to the meninges (in the brain). It is caused by Streptococcus pneumonia, Neisseria meningtidis, Haemophilus influenza. Symptoms include high fever, stiff neck, severe headache, confusion, and sensitivity to light.

Bacterial septicemia

Infection of the blood caused by bacteria leads to increased toxins in the bloodstream passes to the entire body develops organ damage. It occurs due to urinary tract infections, lung infections, kidney infections, and infection in the abdominal area. Symptoms include irregular heartbeat, fever, chills, breathing fast, reduces urine volume, red dots, and shock.

Mahacloxin 250 mg/250 mg Capsule is prescribed in the following indications such Bacterial infections, urinary tract infections, endocarditis, genitourinary tract infections, Gonorrhea, respiratory tract infection, bacterial meningitis.

The Mahacloxin 250 mg/250 mg Capsule contains Ampicillin and Dicloxacillin it is a combination of two medicines. Ampicillin and Dicloxacillin is a penicillin derivative that has a bactericidal effect that produces its action by killing the bacterial cell wall which is needed for the multiplication of bacteria.

The Mahacloxin 250 mg/250 mg Capsule contains Ampicillin and Dicloxacillin it is a combination of two medicines. Ampicillin and Dicloxacillin is a penicillin derivative that has a bactericidal effect that produces its action by killing the bacterial cell wall which is needed for the multiplication of bacteria.

•  It is contraindicated to use this medicine along with live bacterial vaccines
• Do not take this medicine if you are allergic to penicillins, cephalosporins, and Carbapenems
• It is contraindicated to use this medicine in patients who did not have the suspected bacterial infection because it may increase the risk for developing drug-resistance bacteria

• Urticaria
• Diarrhea
• Anemia
• Fever
• Nephritis
• Pseudomembranous colitis
• Rash
• Black hairy tongue
• Diarrhea
• Enterocolitis
• Glossitis
• Oral candidiasis

• Is it safe to give Mahacloxin 250 mg/250 mg Capsules to children suffering from Jaundice?

Kindly avoid taking this medicine if your children have jaundice. Because dicloxacillin present in the medicine may aggravate the symptoms of jaundice in your child.

• Is Mahacloxin 250 mg/250 mg Capsule safe for children suffering from infectious mononucleosis?

No, it is not safe to consume Mahacloxin 250 mg/250 mg Capsule if your child is suffering from mononucleosis and leukemia this may lead to the development of skin rashes.

• Can I get my child vaccinated while on treatment with the Mahacloxin 250 mg/250 mg Capsule?

The use of antibiotics does not interfere with the ingredients in the vaccines. But as a preventive measure do not vaccinate your children until they recover from the illness.

Alcohol

Since it is used in children's no information is available regarding the use of this medicine. Kindly consult with your doctor

Driving or operating machinery

Since it is used in children's no information is available regarding the use of this medicine. Kindly consult with your doctor

Pregnancy

Since it is used in children's no information is available regarding the use of this medicine. Kindly consult with your doctor

Breast Feeding

Since it is used in children's no information is available regarding the use of this medicine. Kindly consult with your doctor

Kidney Problem

The medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

Liver Disease

It is considered safe to use this medicine if you have liver dysfunctions. It does not require dose modification. Kindly consult with your doctor

The Mahacloxin 250 mg/250 mg Capsule is taken orally with or without food. You should not chew, cut or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.

It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.

It is considered to be unsafe to use this medicine in children who are below 3 months old. Kindly consult with your doctor.

Since it is used in children's no information is available regarding the use of this medicine. Kindly consult with the doctor

• Therapy should be administered with caution in patients who are allergic to cephalosporins
• Kindly adjust the dose in patients who are having renal failure
• Use this medicine for only high-risk patients as an endocarditis prophylaxis
• Kindly avoid this medicine if you have developed rash
• Kindly monitor the patient's prothrombin time if there are taking the warfarin concurrently
• In long term, the use of this medicine may cause superinfection
• Therapy should be administered with caution because the elimination of this drug in neonates is slow

Antibiotic resistance

• Finish the complete course of antibiotics even if you feel better. Otherwise, it will lead to Antibiotic resistance (the bacteria may be resistant to antibiotics).

• You have a history of gastrointestinal disease
• You are not responding to the treatment
• You are having any concomitant diseases

Mahacloxin 250 mg/250 mg Capsule contains Ampicillin and Dicloxacillin used to treat bacterial infections such as urinary tract infections, endocarditis, genitourinary tract infections, Gonorrhea, respiratory tract infection, bacterial meningitis.

Ampicillin and Dicloxacillin is a penicillin derivative that has a bactericidal effect that produces its action by killing the bacterial cell wall which is needed for the multiplication of bacteria.

Drug-Drug Interaction

BCG vaccine live

The use of this drug is contraindicated because the use of ampicillin decreases the effect of the BCG vaccine live by pharmacodynamic synergism

Demeclocycline

Use alternative drugs because the use of demeclocycline decreases the effect of ampicillin by pharmacodynamic antagonism

Mycophenolate

Use an alternative drug because the combination of this drug either increases the effect of the other by decreasing its renal clearance.

Aspirin

Therapy should be administered with caution because the combination of this medicine either increases the effect of the other by plasma protein binding competition.

Chloroquine

Therapy should be administered with caution because the use of chloroquine decreases the effect of ampicillin by inhibiting the absorption of GI

Mestranol

Therapy should be administered with caution because the use of dicloxacillin will decrease the effect of mestranol by altering the intestinal flora and it also increases the risk for contraceptive failures

Drug-Food Interaction

Therapy should be administered one hour before or two hours after your food because the use of this medicine may alter the absorption of the medicine

Drug-Disease Interaction

Colitis:

Therapy should be administered with caution in patients with a history of gastrointestinal diseases includes colitis, pseudomembranous colitis. And Clostridioides difficle associated diarrhea was reported while you are using antibacterial drugs.\

Marrow toxicity:

Therapy should be administered with caution in patients who are having a history of blood dyscrasias because the use of this medicine may be associated with adverse effects like neutropenia, leucopenia, granulocytopenia, and thrombocytopenia

Cystic fibrosis:

Therapy should be administered with caution because of renal elimination of this medicine increase in patients with cystic fibrosis.

Hemodialysis:

During Hemodialysis penicillin antibiotics get removed from the body. So doses should be rescheduled after the dialysis process

Mononucleosis:

Ampicillin should not be used in patients with mononucleosis because they develop pruritic erythematous maculopapular skin rash which occurs after 5-10 days of therapy

Renal dysfunction:

The serum concentration of beta-lactam antibiotics increases the half-life in a patient with impaired renal functions. Depending upon your renal function dose should be adjusted

Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.

Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).

• Stored at 10-30°C room temperature.
• Protect from light and heat.
• Keep away from children and pets. Otherwise, it becomes toxic to them.
• Disposed of properly in a suitable bag.

Ampicillin is a penicillin derivative that is effective against both gram-negative and gram-positive bacteria and helps to kill the bacteria. Dicloxacillin is an antibiotic used to treat bacterial infections which mainly targets the lungs, ear, nasal sinus, urinary tract, and skin infections in children.

Take it with food and plenty of water to avoid stomach upset and kindly consult with your doctor, If you have a rash, swelling of the face, difficulty in breathing while you are taking this medicine.

Kindly complete a full course of treatment as per the doctor's prescriptions. If you withdraw the medicine when you feel better it may worsen your condition.