Malirid 45mg Tablet

Malirid 45mg Tablet contains Primaquine 45mg used to treat parasitic infections such as Malaria. Primaquine is an 8-Aminoquinoline antimalarial drug that results in interacting with certain substances which are required for the malarial parasitic cells present in our blood for their vital functions. It is usually effective against plasmodium vivax, and Plasmodium ovale strains of malarial parasites. It produces its action by killing the parasite that causes infection and also helps to prevent the infections.

It is used in the treatment of the following conditions as parasitic infections such as Malaria

Parasitic infections

It is an organism that lives in another organism like your body for its food and place to survive. You can get a parasitic infection from contaminated water, food, bug bites o sexual contact. It is a one-celled organism called protozoa which can be seen in the naked eye. Symptoms include stomach pain, nausea, vomiting, dehydration, weight loss, inflamed lymph nodes, constipation, diarrhea, rashes, eczema, hives, muscle, and joint pain.

Malaria

Malirid 45mg Tablet (Primaquine) is used to treat the uncomplicated malaria disease (caused by a parasite), which leads to developing a fever, chills, nausea, vomiting, headache, muscle pain, etc.

The Malirid 45mg Tablet is prescribed in the following indications as Malaria

The Malirid 45mg Tablet containing Primaquine 45mg is an 8-Aminoquinoline antimalarial drug that produces its action by increasing the time (a toxic substance to parasites) in your blood. This kills the parasite that is present in your blood and inhibits the growth of bacteria that cause infections.

The Malirid 45mg Tablet containing Primaquine 45mg is an 8-Aminoquinoline antimalarial drug that produces its action by increasing the time (a toxic substance to parasites) in your blood. This kills the parasite that is present in your blood and inhibits the growth of bacteria that cause infections.

• Do not take this medicine if you are allergic to Primaquine
• It is contraindicated to use this medicine in patients who are having a severe glucose-6-phosphate dehydrogenase deficiency.
• Primaquine should not be recommended in patients receiving hemolytic, and bone marrow depressant drugs, which leads to worsening the patient health conditions
• Patients who are suffering from the systemic disease may tend to develop granulocytopenia such as rheumatoid arthritis and lupus erythematosus.

• Abdominal pain
• Hemolytic anemia in G6PD deficiency
• Agranulocytosis
• Arrhythmias
• Leukopenia
• Leukocytosis
• Dizziness
• Rash
• Methemoglobinemia

• How long should I take the Malirid 45mg Tablet?

Normally the duration of this medicine depends upon the severity of the disease. You should take this according to your doctor advice

• Is the Malirid 45mg Tablet is safe?

Yes, it is considered safe when you have taken the medication as per the dose and duration advised by the doctor. If you stop the medicine without completing the course of treatment it may worsen the conditions

• What if I do not get better after using the Malirid 45mg Tablet?

If you do not feel better after completing the full course of treatment kindly inform your doctor.

Alcohol

The use of alcohol may produce harmful effects while you are receiving this treatment. Kindly consult with your doctor.

Driving or operating machinery

It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

Pregnancy

The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects on the fetus. Kindly consult with your doctor

Breast Feeding

The use of this medicine is considered unsafe during breastfeeding because it may excrete via breast milk. Kindly consult with your doctor

Kidney Problem

Limited information is available regarding the use of this medicine in patients who are having a renal impairment. Kindly consult with your doctor.

Liver Disease

Limited information is available regarding the use of this medicine in patients who are having a hepatic impairment. Kindly consult with your doctor.

Malirid 45mg Tablet is taken orally with or without food. You should not chew, cut or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.

It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.

It is considered unsafe to use this medicine in children who are below 16 years old. Kindly consult with your doctor.

Malirid 45mg Tablet should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.

• The use of this medicine may develop tolerance if you have a history of idiosyncrasy to primaquine, family history of favism, glucose-6-phosphate dehydrogenase deficiency.
• Monitor the patient's ECG while using primaquine in patients who are with cardiac disease, long QT syndrome, a history of ventricular arrhythmias, uncorrected hypokalemia, hypomagnesemia, or bradycardia.

• You have a history of gastrointestinal disease
• You are not responding to the treatment
• You have experienced any allergic reaction like rashes and itching
• You are having a concomitant disease or taking any medications

Malirid 45mg Tablet consist of Primaquine 45mg is used to treat Malaria diseases (caused by plasmodium vivax, and Plasmodium ovale strains of malarial parasite).

Primaquine 45mg is an 8-Aminoquinoline antimalarial drug, helpful in eradicating malarial infection. Also, used with other antimalarial drugs for the radical treatment of malaria.

Drug-Drug Interaction

Lefamulin

The use of this drug is contraindicated because the use of lefamulin will increase the effect of primaquine by affecting its hepatic and intestinal enzyme metabolism.

Deferiprone

Use alternative drugs because the combination of this drug either increases the toxicity of the other by pharmacodynamic synergism.

Quinacrine

Use alternative drugs because the use of quinacrine increases the level of primaquine by unspecified interaction mechanism.

Ifosfamide

Therapy should be administered with caution because the combination of this drug either increases the toxicity of the other by pharmacodynamic synergism and it also increases the risk of developing myelosuppression

Probenecid

The combination of this drug increases the risk for developing hemolysis in G6PD deficiency

Drug-Food Interaction

No interaction was found while using this medicine

Drug-Disease Interaction

Hemolytic anemia/G6PD Deficiency

Malirid 45mg Tablet (Primaquine 45mg) should not be recommended in patients with Hemolytic anemia/G6PD deficiency (leads to develop low hemoglobin levels or deficiency of G6PD enzyme), which leads to worsening the patient health conditions.

Methemoglobinemia/NADH methemoglobin reductase deficiency

Malirid 45mg Tablet (Primaquine 45mg)should not be recommended in patients with Methemoglobin (caused due to the deficiency of NADH-methemoglobin reductase enzyme), which leads to worsening the patient health conditions.

Granulocytopenia

Malirid 45mg Tablet (Primaquine 45mg)should not be recommended in patients with granulocytopenia (systemic diseases include Rheumatoid arthritis, leucopenia, etc. leads to decreases in granulocyte blood cells), leads to developing reduction of immune system capabilities. Then it leads to worsening the patient's health conditions.

Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.

Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).

• Stored at 10-30°C room temperature.
• Protect from light and heat.
• Keep away from children and pets. Otherwise, it becomes toxic to them.
• Disposed of properly in a suitable bag.

Malirid 45mg Tablet contains Primaquine 45mg used to treat parasitic infections such as Malaria. Primaquine 45mg is an 8-Aminoquinoline antimalarial drug, results in interacting with certain substances (required for vital functions of the malarial parasite cell) present in the blood. Then it eradicates the malarial infection caused by plasmodium vivax and Plasmodium ovale strains of malarial parasite. Also, used with other antimalarial drugs for the radical treatment of malaria.