Drug Interaction of Naprofast P Tablet
Ketoconazole is used in the treatment fungal infection as an anti-fungal agent.
This combinational medicine along with the ketoconazole reduces the stomach acid and decreases the absorption of ketoconazole in the body and reduces the blood levels of ketoconazole in the blood levels. Because of this antifungal effect will be reduced.
Methotrexate along with this combinational medicine may increase the blood levels and side effects of methotrexate. So dose adjustment is needed kindly consult with your doctor.
This combinational medicine by decreasing the stomach acid levels, pantoprazole may decrease the absorption and reduces the blood levels of nelfinavir. Because of this, the medication becomes less effective against HIV.
Warfarin is an anticoagulant drug. This combinational medicine increases the levels of warfarin in our body leads to an increase in International Normalized Ratio (INR) levels. This may causes the risk of serious bleeding. Dose adjustment and frequent monitoring patient prothrombin timing or INR levels are necessary. Kindly consult with your doctor.
By using of this medicine with food should be maintained time gap at least 1 hour before the meals for better effectiveness of the medicine. By using of this medicine with spicy, fatty foods, alcohol, caffeinated drinks, or beverages such as coffee, tea, cola, etc, should be avoided for better effectiveness of the medicine.
It should be used with caution in patients with gastrointestinal perforations (intestinal problems such as internal bleeding, an obstruction, or perforation of the stomach, and intestine, etc) leads to worsen the patient health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.
This combinational tablet should be used with caution in patients with liver impairment, or liver diseases. Then it leads to a risk of liver problem or liver damage. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.
By using the medicine for the very longer period of this time leads the osteoporosis (Bone fracture). To avoid the osteoporosis calcium and others vitamin D supplement are give to minimize the calcium and vitamin deficiency. Kindly consult with your doctor.
The patients with heart problem, caution should be taken before taking the medicine otherwise leads to the heart-related problems such as heart failure, etc which leads to the patient conditions most worsening. Kindly consult with your doctor before prescribing the medicine based on the health or clinical conditions, dose adjustment or replacement is necessary.