Brand Name Nervz NT Tablet SR
Salt Composition

Pregabalin (75mg) + Nortriptyline (10mg)

Strength 75mg + 10mg
Product Form Tablet SR
Pack 10 Tablets in 1 Strip
Storage Store below 30°C
Category

Anticonvulsant and Antidepressant

SubCategory

Neuropathic pain

Country of Origin India
Manufacturer

Intas Pharmaceuticals Ltd

Manufacturer/Marketer Address Intas Pharmaceuticals Ltd,Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
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M.R.P : Rs.301.00       Price : Rs.240.80

You Save : Rs.60.20    Inclusive of all taxes

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10 Tablets in 1 Strip

Availability : In Stock

  Online Payment Only

  Non Returnable Read More



    Medical Description of Nervz NT Tablet SR

    The Nervz NT Tablet SR contains Pregabalin 75mg and Nortriptyline 10mg is a combination of anticonvulsants and antidepressants used to treat neuropathic pain. The combination of this medicine produces its action by inhibiting the movement of pain signals in your brain and reduces pain.


    Nervz NT Tablet SR Uses

    It is used in the treatment of neuropathic pain


    Nervz NT Tablet SR Benefits

    Neuropathic pain

    It is often described as shooting or burning pain. It is usually caused by alcoholism, diabetes, facial nerve problems, HIV infection, stroke, Parkinson's disease, multiple sclerosis, and shingles. The symptoms include shooting, burning, stabbing, electric shock-like pain, tingling, numbness, or pins and needles


    Nervz NT Tablet SR Indication

    The Nervz NT Tablet SR is prescribed for the following indications as neuropathic pain


    Mechanism of action of Nervz NT Tablet SR

    The Nervz NT Tablet SR contains Pregabalin 75mg and Nortriptyline 10mg is a combination of anticonvulsants and antidepressants. Pregabalin is an antiepileptic medication that produces its action by decreasing the abnormal electrical activity in your brain. It also treats nerve pain by interfering with the pain signals which is present in your brain and treating damaged nerves.

    Nortriptyline an antidepressant that produces its action by increasing the level of chemical messengers in your brain that helps to regulate your mood and treat depression.


    How Nervz NT Tablet SR works

    The Nervz NT Tablet SR contains Pregabalin 75mg and Nortriptyline 10mg is a combination of anticonvulsants and antidepressants. Pregabalin is an antiepileptic medication that produces its action by decreasing the abnormal electrical activity in your brain. It also treats nerve pain by interfering with the pain signals which is present in your brain and treating damaged nerves.

    Nortriptyline an antidepressant that produces its action by increasing the level of chemical messengers in your brain that helps to regulate your mood and treat depression.


    Nervz NT Tablet SR Contraindication

    Do not take this medicine if you are allergic to Pregabalin and Nortriptyline


    Nervz NT Tablet SR Side Effects

    • Dizziness
    • Sedation
    • Peripheral edema
    • Fatigue
    • Weight gain
    • Blurred vision
    • Headache
    • Dry mouth
    • Constipation
    • Diarrhea


    FAQs for Nervz NT Tablet SR

    • For how long should I take the Nervz NT Tablet SR?

    The duration of the treatment is as short as possible. Do not stop the medicines suddenly when you feel better it may produce withdrawal syndrome. So your doctor may gradually decrease the medicines to avoid withdrawal side effects.

    • Is the Nervz NT Tablet SR addictive?

    Yes, the people who are taking this medicine for a long period may lead to addiction. And also people with a history of alcoholism and drug abuse are more prone to become addicted.

    • Is the Nervz NT Tablet SR safe?

    Yes, the use of this medicine is considered safe if you use this medicine as per the dose and duration advice by your doctor.


    Precautions and general warning of Nervz NT Tablet SR

    Alcohol

    It is considered unsafe to consume alcohol while taking this medication. Kindly consult with your doctor

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine because the use of this medicine may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    It is considered unsafe during pregnancy because it may produce harmful effects on the fetus. Kindly consult with your doctor.

    Breast Feeding

    It is considered unsafe to use this medicine during breastfeeding because it may excrete via breast milk. Kindly consult with your doctor

    Kidney Problem

    This medicine should be used with caution in patients with kidney impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    It is considered safe to use this medicine in patients with liver problems. Kindly consult with your doctor


    How to Take Nervz NT Tablet SR

    The capsule is taken orally with or without food. You should not chew, cut or crush the capsule. Take this medicine as per the dose and duration advised by your doctor. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Nervz NT Tablet SR in Adult

    It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.


    Use of Nervz NT Tablet SR in children

    Safety and efficacy were not established in children. Kindly consult with your doctor.


    Use of Nervz NT Tablet SR in Elderly Patients

    The Nervz NT Tablet SR should be used with caution in patients in an elderly age group, which leads to developing further medical problems, leading to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The use of this medicine may cause peripheral edema, dizziness, sedation, weight gain, and prolongation of the PR interval
    • The use of this medicine increases the risk of suicidal thoughts, angioedema
    • Monitor for the platelet count while you are receiving this medicine
    • Therapy should be administered with caution in patients with urinary retention, hyperthyroidism, seizure disorder, brain tumor, respiratory impairment, bipolar mania
    • The use of this medicine may cause bone marrow suppression, orthostatic hypotension, and sedation
    • The use of this medicine may increase the risk of anticholinergic side effects, and mydriasis
    • Therapy should be administered with caution in patients with cardiovascular disease, diabetes mellitus, hepatic and renal impairment


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reactions like rashes and itching
    • You are suffering from depression
    • You have watery diarrhea, stomach pain, and fever


    General instructions

    Pregabalin 75mg and Nortriptyline 10mg are a combination of anticonvulsants and antidepressants used to treat neuropathic pain. The combination of this medicine produces its action by inhibiting the movement of pain signals in your brain and reduces pain.


    Drug Interaction of Nervz NT Tablet SR

    Drug-Drug Interaction

    Dronedarone + Nortriptyline

    Dronedarone will increase the effect of nortriptyline by affecting the patient's hepatic enzyme metabolism. The use of this drug is contraindicated because it increases the risk of ventricular tachycardia

    Albuterol + Nortriptyline

    The use of this drug may increase or decrease the effect of sympathomimetics by inhibiting the  uptake of sympathomimetics into the adrenergic neuron

    Citalopram + Nortriptyline

    A combination of these drugs increases serotonin levels. Use alternative drugs because citalopram increases the risk of serotonin syndrome and OT prolongation. Closely monitor the patient's ECG

    Benazepril + Pregabalin

    Coadministration increases the risk of developing angioedema of the face, mouth, and neck. Angioedema may result in respiratory compromise.

    Clobazam + Pregabalin

    Concomitant administration can increase the potential for CNS effect. The combination of these drugs may increase sedation or respiratory depression.

    Lurasidone + Pregabalin

    The combination of this drug may increase the toxicity of the other because it increases the risk of CNS depressant effect

    Drug-Food Interaction

    Alcohol

    Alcohol may alter the effect of tricyclic antidepressants and cause increased side effects such as irregular heartbeat, drowsiness, confusion, agitation, vomiting, blurred vision, sweating, muscle stiffness, feeling light-headed, and seizure. Do not stop this medicine without consulting with your doctor

    Drug-Disease Interaction

    Anticholinergic effects + Nortriptyline

    Tricyclic anti-depressants should be administered with caution in a patient with anticholinergic activity such as urinary retention, angle-closure glaucoma, untreated intraocular hypertension, and gastrointestinal obstructive disorders.

    Cardiovascular diseases + Nortriptyline

    During the initiation of the therapy tricyclic antidepressants may cause orthostatic hypotension, reflux tachycardia, syncope, and dizziness. Therapy should not be administered with caution in patients during the acute recovery phase following myocardial infarction, hyperthyroidism, or a history of cardiovascular disease. Closely monitor the patient's ECG levels.

    Bone marrow suppression+ Nortriptyline

    Therapy should be administered with caution in a patient with bone marrow suppression because the use of tricyclic anti-depressants may increase the risk of bone marrow suppression, leukopenia, agranulocytosis, thrombocytopenia, anemia, eosinophilia

    Bipolar disorder + Nortriptyline

    Therapy should be administered with caution in a patient with bipolar disorder because the use of tricyclic anti-depressants may precipitate the symptoms of psychosis in bipolar disorder patients

    Renal/Liver disease + Nortriptyline

    Therapy should be administered with caution in a patient with renal and hepatic function because there is limited information available regarding the use of tricyclic anti-depressants in a patient with renal and hepatic impairment.

    Angioedema + Pregabalin

    Therapy should be administered with caution in a patient with angioedema because the use of pregabalin may increase the risk of developing angioedema

    Creatinine Kinase Elevations + Pregabalin

    Therapy should be administered with caution in a patient with elevated creatine kinase levels because the use of pregabalin may be associated with creatine kinase elevations

    Peripheral edema + Pregabalin

    The use of pregabalin is contraindicated in patients with congestive heart failure because the use of pregabalin may increase the risk of peripheral edema

    Drug dependence + Pregabalin

    Therapy should be administered with caution in patients with a history of alcohol or substance abuse because the use of an anxiolytic agent can cause dependence and abuse. Dose reduction is necessary.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose on this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • The Nervz NT Tablet SR contains Pregabalin 75mg and Nortriptyline 10mg is a combination of anticonvulsants and antidepressants used to treat neuropathic pain.
    • The combination of this medicine produces its action by inhibiting the movement of pain signals in your brain and reduces pain.
    • Inform your doctor if you have a history of seizures or if you have experienced hallucinations, fever, sweating, irregular heartbeat, and loss of coordination
    • Do not stop taking this medicine without consulting with a doctor