New Okaflox M Syrup

Brand Name New Okaflox M Syrup
Salt Composition

Ofloxacin (50mg) + Metronidazole (100mg)

Strength 50mg + 100mg
Product Form Syrup
Pack 1 x 60ml in 1 Bottle
Storage Store below 30°C
Category

Antibiotic

SubCategory

Anti-Biotic

Country of Origin India
Manufacturer

Cipla Ltd

Manufacturer/Marketer Address Cipla Ltd,Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
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M.R.P : Rs.37.30       Price : Rs.33.57

You Save : Rs.3.73    Inclusive of all taxes

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1 x 60ml in 1 Bottle

Availability : In Stock

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  Non Returnable Read More



    Medical Description of New Okaflox M Syrup

    New Okaflox M Syrup contains Ofloxacin 50mg and Metronidazole 100mg used to treat both bacterial and parasitic infections such as Diarrhea and Dysentery in children.  Mainly this medicine targets infection of the teeth, lungs, gastrointestinal tract, urinary tract, and genital tract. Metronidazole is a Nitroimidazole derivative Antibacterial and Antiprotozoal drug which kills parasites and anaerobic bacteria. Ofloxacin is an antibiotic that helps to inhibit the growth of infection.


    New Okaflox M Syrup Uses

    It is used in the treatment of the following conditions as bacterial and protozoal infections such as Diarrhea and Dysentery in children.


    New Okaflox M Syrup Benefits

    Bacterial infections

    Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

    Parasitic infections

    It is an organism that lives in another organism like your body for its food and place to survive. You can get a parasitic infection from contaminated water, food, bug bites o sexual contact. It is a one-celled organism called protozoa which can be seen in the naked eye. Symptoms include stomach pain, nausea, vomiting, dehydration, weight loss, inflamed lymph nodes, constipation, diarrhea, rashes, eczema, hives, muscle, and joint pain.

    Infectious diarrhea

    Infection to the digestive tract leads to increased frequency of bowel movements or loose watery bowel movements caused by bacteria called diarrhea. It leads to worsening the patient’s health condition. This medicine is used to treat this bacterial infection.

    Dysentery

    It is also called infectious diarrhea. Inflammation of the gut (intestine) leads to bloody stools or watery stools. It is most often caused by shigella bacteria (shigellosis) or an amoeba (parasite), spreading through contaminated food or water. This medicine is used to treat this bacterial infection.


    New Okaflox M Syrup Indication

    The New Okaflox M Syrup is prescribed in the following indications as bacterial and protozoal infections such as Diarrhea and Dysentery in children.


    Mechanism of action of New Okaflox M Syrup

    The New Okaflox M Syrup contains Ofloxacin 50mg and Metronidazole 100mg it is a combination of two medicine. Ofloxacin is a quinolone antibiotic that produces its action by inhibiting the activity of a bacterial enzyme called DNA gyrase and preventing the bacterial cell from reproduction and repairing themselves and killing the bacteria which is responsible for the infection. Metronidazole is nitroimidazoles that produce its action by damaging their DNA and killing the parasites and anaerobic bacteria which is responsible for infections.


    How New Okaflox M Syrup works

    The New Okaflox M Syrup contains Ofloxacin 50mg and Metronidazole 100mg it is a combination of two medicine. Ofloxacin is a quinolone antibiotic that produces its action by inhibiting the activity of a bacterial enzyme called DNA gyrase and preventing the bacterial cell from reproduction and repairing themselves and killing the bacteria which is responsible for the infection. Metronidazole is nitroimidazoles that produce its action by damaging their DNA and killing the parasites and anaerobic bacteria which is responsible for infections.


    New Okaflox M Syrup Contraindication

    • Do not take this medicine if you are allergic to Metronidazole and Ofloxacin
    • It is contraindicated to use this medicine in 1st trimester of pregnancy
    • It is contraindicated to consume alcohol while you are receiving these medicines
    • The use of fluoroquinolones associated with side effects include tendinitis, tendon rupture, peripheral neuropathy, and the central nervous system effects
    • It is contraindicated to use this medicine in patients who are having a history of myasthenia gravis


    New Okaflox M Syrup Side Effects

    • Loss of appetite
    • Candidiasis
    • Diarrhea
    • Dizziness
    • Ataxia
    • Dark urine
    • Furry tongue
    • Neutropenia
    • Metallic taste
    • Joint pain
    • Excessive gas in the stomach
    • Fever
    • Dry eyes


    FAQs for New Okaflox M Syrup

    • What if I do not get better after using the New Okaflox M Syrup?

    If you do not feel better after completing the full course of treatment kindly inform your doctor.

    • Is the New Okaflox M Syrup is effective?

    Yes, it is considered effective when you have taken the medication as per the dose and duration advised by the doctor. If you stop the medicine without completing the course of treatment it may worsen the conditions

    • Can I stop taking New Okaflox M Syrup when I feel better?

    No, you should not stop the medicine on your own until you complete a full course of treatment because it may worsen your conditions.

    • Can I get my child vaccinated while on treatment with New Okaflox M Syrup?

    The use of antibiotics does not interfere with the ingredients in the vaccines. But as a preventive measure do not vaccinate your children until they recover from the illness.


    Precautions and general warning of New Okaflox M Syrup

    Alcohol

    Since it is used in children's no information is available regarding the use of this medicine. Kindly consult with your doctor

    Driving or operating machinery

    Since it is used in children's no information is available regarding the use of this medicine. Kindly consult with your doctor

    Pregnancy

    Since it is used in children's no information is available regarding the use of this medicine. Kindly consult with the doctor

    Breast Feeding

    Since it is used in children's no information is available regarding the use of this medicine. Kindly consult with the doctor

    Kidney Problem

    Therapy should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    Therapy should be used with caution in patients with hepatic impairment. The use of this medicine required dose modification. Kindly consult with your doctor.


    How to Take New Okaflox M Syrup

    New Okaflox M Syrup is taken orally with or without food. You can measure the dose with the help of a measuring cup and shake well before using this Syrup. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of New Okaflox M Syrup in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.


    Use of New Okaflox M Syrup in children

    It is considered unsafe to use this medicine in children who are below 6 months old. Kindly consult with your doctor.


    Use of New Okaflox M Syrup in Elderly Patients

    Since it is used in children's no information is available regarding the use of this medicine. Kindly consult with the doctor


    Other general warnings

    • At long-term treatment seizure and aseptic meningitis were reported
    • The use of this medicine may cause encephalopathy and peripheral neuropathy
    • Kindly avoid using this medicine in absence of any suspected bacterial or parasitic infection because it increases the risk of developing drug-resistant bacteria and parasites
    • Therapy should be administered with caution in patients who are having hepatic and renal impairment, heart failure, and H.pylori infection
    • Use this medicine with care in patients who are having a history of blood dyscrasia, agranulocytosis, leucopenia, and neutropenia
    • Kindly avoid receiving this medicine along with antiandrogen because it may cause gynecomastia
    • You may develop fatal hypoglycemia in elderly people who are with or without diabetes
    • Avoid sunlight because the use of this medicine can cause photosensitivity
    • There is an increased risk for developing fluoroquinolone associated tendinitis and tendon rupture in patients who are over 60 years of age
    • Convulsions increased intracranial pressure, and toxic psychosis was reported while you are using fluoroquinolones
    • At long-term use, it may cause fungal or bacterial superinfection
    • The use of this medicine may cause C difficile associated colitis

                Tendinitis and Tendon rupture (Muscle damage)

    • This medicine causes tendinitis and tendon rupture, which mainly affects your shoulder, hands, ankles, or other joint parts of your body. And muscle damage also occurs usually on the tendons surrounding the muscles. It may experience pain, numbness, or tingling sensations in your muscles. It should be a risk in patients of more than 60 years of age or undergone a transplant of kidney, heart, or lung. If necessary, then needs dose adjustment or replacement

                Diarrhea

    • This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. It leads to worsening the patient’s health condition. Better to take probiotics with this medicine to avoid diarrhea.

                Antibiotic resistance

    • Finish the complete course of antibiotics even if you feel better. Otherwise, it will lead to Antibiotic resistance (the bacteria may be resistant to antibiotics)

                Dialysis

    • Using this medicine doesn’t show effects in patients on dialysis. This medicine should be scheduled before or after the dialysis procedure.


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have a Glucose-6 phosphate dehydrogenase


    General instructions

    Metronidazole is nitroimidazoles that produce its action by damaging their DNA and killing the parasites and anaerobic bacteria which is responsible for infections. Ofloxacin is a fluoroquinolone antibiotic used to treat bacterial infection by preventing the bacteria from reproduction and repairing themselves. Mainly bacterial infection targets the nose, throat, lungs, skin and soft tissues, bone and joints, genitals, and urinary tract.


    Drug Interaction of New Okaflox M Syrup

    Drug-Drug Interaction

    Dronabinol

    The use of this drug is contraindicated because the use of Metronidazole increases the toxicity of dronabinol by inhibiting aldehyde dehydrogenase

    Flibanserin

    The use of this drug is contraindicated because the use of metronidazole will increase the effect of flibanserin by affecting its hepatic and intestinal enzyme metabolism

    Mebendazole

    Use alternative drug because the use of mebendazole increase the toxicity of metronidazole by increasing the risk of developing toxic epidermal necrolysis

    Warfarin

     Use alternative drugs because the use of metronidazole increases the effect of warfarin by decreasing its metabolism

    Aluminum hydroxide

    Use alternative drugs because the use of aluminum hydroxide decreases the effect of Ofloxacin by inhibiting the GI absorption

    Escitalopram

    Therapy should be administered with caution because the use of escitalopram increase the toxicity of Ofloxacin by QTc interval

    Estradiol

    Therapy should be administered with caution because the use of Ofloxacin decreases the effect of estradiol by altering the intestinal flora and it also lowers the risk of contraceptive failure.

    Drug-Food Interaction

    The use of alcohol with metronidazole may produce some disulfiram reactions such as flushing, throbbing in the head and neck, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, lightheadedness, blurred vision, and confusion.

    Drug-Disease Interaction

    Neurologic toxicity

    Using this medicine should be cautious in patients with neurological toxicity (convulsions and peripheral neuropathy) leads to develop numbness, tingling, or burning sensation of hands and feet like neurological effects leads to worsening the patient health condition.

    Blood Dyscrasias

    Using this medicine should be cautious in patients with blood Dyscrasias (low blood count) leads to a decrease in the blood cell count tends to develop leukopenia, thrombocytopenia, and bone marrow aplasia. It leads to worsening the patient's health condition.

    Kidney diseases

    It should be used with caution in a patient with renal impairment or kidney disease. Then it develops the risk of kidney damage. Inform your doctor and then take. Based on the patient's health condition, dose adjustment or replacement of medicine is needed.

    Liver diseases

    It should be used with caution in a patient with hepatic impairment or liver disease. Then it develops a risk of liver damage. Inform your doctor and then take. Based on the patient's health condition, dose adjustment or replacement of medicine is needed.

    Central nervous system disorders

    Using this medicine is needs caution in patients with seizures, other central nervous system abnormalities, or fits. It causes hallucinations, anxiety, confusion, and restlessness, etc. Inform the doctor, then will do dose adjustment or replacement is needed. If necessary to take this medicine with seizure medications.

    Colitis

    This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This drug should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient’s health condition.

    QT prolongation

    This drug should be used with caution in patients with heart-related problems such as irregular heart rate, in which this drug alters the heart rate.

    Kidney diseases

    It should be used with caution in a patient with renal impairment or kidney disease. Then it leads to the risk of kidney damage. Based on the patient clinical condition, adjust the dose accordingly


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    New Okaflox M Syrup contains Ofloxacin 50mg and Metronidazole 100mg used to treat both bacterial and parasitic infections such as Diarrhea and Dysentery in children. Mainly this medicine targets infection of the teeth, lungs, gastrointestinal tract, urinary tract, and genital tract.

    Metronidazole is a Nitroimidazole derivative Antibacterial and the Antiprotozoal drug is used to kill other infectious microorganisms in addition to bacteria or protozoa by binding their DNA. Also used as prophylaxis drug of sexually transmitted disease. Ofloxacin is a fluoroquinolone antibiotic used to treat bacterial infection by preventing the bacteria from reproduction and repairing themselves.

    This medicine is not used for common flu and cold symptoms. And not treat viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial and parasitic infections.

    This medicine is contraindicated to allergic symptoms such as skin rash, itching, swelling, and breathing difficulties.