Nizol 200mg Tablet

Brand Name Nizol 200mg Tablet
Salt Composition

Ketoconazole (200mg)

Strength 200mg
Product Form Tablet
Pack 10 Tablet(s) in Strip
Storage Store below 30°C
Category

Antifungal

SubCategory

anti-fungal

Country of Origin India
Manufacturer

Intas Pharmaceuticals Ltd

Manufacturer/Marketer Address Intas Pharmaceuticals Ltd,Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
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M.R.P : Rs.260.00       Price : Rs.239.20

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10 Tablet(s) in Strip

Availability : Sold Out

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    Medical Description of Nizol 200mg Tablet

    Nizol 200mg Tablet contains Ketoconazole 200mg used to treat severe fungal infections such as Blastomycosis, Chromomycosis, Coccidioidomycosis, Histoplasmosis, and Paracoccidioidomycosis. Mainly this targets the mouth, throat, vagina, and other parts like fingernails and toenails. Ketoconazole is an antifungal medication that kills the fungus that causes infection by destroying their cell membrane


    Nizol 200mg Tablet Uses

    Nizol 200mg Tablet is used in the treatment of the following conditions as fungal infections such as Blastomycosis, Chromomycosis, Coccidioidomycosis, Histoplasmosis, and Paracoccidioidomycosis


    Nizol 200mg Tablet Benefits

    Fungal infections:

    It is also called mycosis. The infection can affect several parts of the body and the common fungal infections are athlete’s foot, josh itch, ringworm, yeast infection, and onychomycosis. Symptoms include skin darkening, peeling rashes, small lump, deformed toenail, itching, or vaginal discharge.

    Blastomycosis

    Blastomyces dermatitidis fungus causes infection to the skin, bones, and joints called Blastomycosis. Ketoz 200mg Tablet (Ketoconazole) is used to treat this fungal infection.

    Chromomycosis

    Fonsecaea pedrosoi, Phialophora verrucosa, and the fungus cause infection to the skin, and subcutaneous tissue called Chromomycosis. Ketoz 200mg Tablet (Ketoconazole) is used to treat this fungal infection.

    Coccidioidomycosis

    Coccidioides fungus causes infection to the lungs, and other body parts called Coccidioidomycosis. Ketoz 200mg Tablet (Ketoconazole) is used to treat this fungal infection.

    Histoplasmosis

    Histoplasma capsulatum fungus causes infection to the lungs, and other body parts called Histoplasmosis. Ketoz 200mg Tablet (Ketoconazole) is used to treat this fungal infection.

    Paracoccidioidomycosis

    Paracoccidioides brasiliensis fungus causes infection to the lungs, and other body parts called Paracoccidioidomycosis..


    Nizol 200mg Tablet Indication

    The Nizol 200mg Tablet is prescribed in the following indications as Blastomycosis, Chromomycosis, Coccidioidomycosis, Histoplasmosis, and Paracoccidioidomycosis


    Mechanism of action of Nizol 200mg Tablet

    Nizol 200mg Tablet contains Ketoconazole 200mg is an azole antifungal drug that produces its action by inhibiting the growth of fungi by destroying the cell membrane and this helps to treat your skin infections


    How Nizol 200mg Tablet works

    Nizol 200mg Tablet contains Ketoconazole 200mg is an azole antifungal drug that produces its action by inhibiting the growth of fungi by destroying the cell membrane and this helps to treat your skin infections


    Nizol 200mg Tablet Contraindication

    • Do not take this medicine if you are allergic to Ketoconazole
    • It is contraindicated to use this medicine along with dofetilide, quinidine, pimozide, cisapride, methadone, and dronedarone
    • It is contraindicated to use this medicine in patients who are having acute and chronic liver disease


    Nizol 200mg Tablet Side Effects

    • Pruritus
    • Abdominal pain
    • Alopecia
    • Dizziness
    • Hyperlipidemia
    • Somnolence
    • Depression
    • Gynecomastia
    • Impotence
    • Thrombocytopenia
    • Leukopenia
    • Hemolytic anemia
    • Orthostatic hypotension
    • Hepatotoxicity


    FAQs for Nizol 200mg Tablet

    • Can the use of a Nizol 200mg Tablet cause diarrhea?

    Yes, the use of this medicine can cause diarrhea because the use of antibiotics kills the harmful bacteria and it also affects the good bacteria in your bacteria. Kindly inform your doctor if you have experienced severe diarrhea

    • What if I do not get better after using the Nizol 200mg Tablet?

    If you do not feel better after completing the full course of treatment kindly inform your doctor.

    • Is the Nizol 200mg Tablet is effective?

    Yes, it is considered effective when you have taken the medication as per the dose and duration advised by the doctor. If you stop the medicine without completing the course of treatment it may worsen the conditions


    Precautions and general warning of Nizol 200mg Tablet

    Alcohol

    The use of alcohol is considered unsafe while you are receiving this medication. Kindly consult with your doctor

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects on the fetus. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered safe during breastfeeding because it does not excrete via breast milk. Kindly consult with your doctor

    Kidney Problem

    It is considered safe to use this medicine in patients with renal impairment and it does not require dose modification. Kindly consult with your doctor.

    Liver Disease

    The medicine should be used with caution in patients with hepatic impairment. The use of this medicine required dose modification. Kindly consult with your doctor


    How to Take Nizol 200mg Tablet

    The Tablet is taken orally with or without food. You should not chew, cut or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence


    Use of Nizol 200mg Tablet in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.


    Use of Nizol 200mg Tablet in children

    It is considered unsafe to use this medicine in children who are below 2 years old. Kindly consult with your doctor.


    Use of Nizol 200mg Tablet in Elderly Patients

    Nizol 200mg Tablets should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • Kindly avoid prescribing tablets to treat skin and nail fungal infection which increase the risk of developing liver damage
    • The use of this medicine may increase the long bone fragility
    • Kindly avoid using this medicine along with the drugs that decrease the gastric acidity
    • It is not used to treat fungal meningitis
    • The use of this medicine may cause hepatotoxicity
    • The use of this medicine along with lovastatin and simvastatin which increases the risk of developing myopathy


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You are using any concomitant medication


    General instructions

    Ketoconazole is an azole antifungal drug that produces its action by inhibiting the growth of fungi by destroying the cell membrane and this helps to treat skin infections


    Drug Interaction of Nizol 200mg Tablet

    Drug-Drug Interaction

    Alfuzosin

    The use of this drug is contraindicated because the combination of this drug increases the QTc interval

    Butabarbital

    The use of this drug is contraindicated because the use of butabarbital decreases the effect of Ketoconazole by increasing its metabolism

    Aminolevulinic acid

    Use alternative drugs because the combination of this drug either increases the toxicity of the other by pharmacodynamic synergism.

    Ketamine

    Use alternative drugs because the use of Ketoconazole will increase the effect of ketamine by affecting its hepatic and intestinal enzyme metabolism.

    Chlorpropamide

    Therapy should be administered with caution because the use of Ketoconazole increases the effect of chlorpropamide by decreasing its metabolism

    Cyclosporine:

    Monitor the combination of this drug because the use of Ketoconazole will increase the effect of cyclosporine by altering its metabolism

    Drug-Food Interaction

    Food may reduce the absorption of Ketoconazole. So it is better to take this medicine on an empty stomach 1 or 2 hours before or after your meals

    Drug-Disease Interaction

    Hepatotoxicity

    Therapy should be administered with caution because the use of Ketoconazole may cause serious hepatic reactions to include hepatitis, cholestasis, fulminant hepatic failure. While receiving this medicine kindly monitor the patient's liver function test.

    QT prolongation:

    Therapy should be administered with caution in patients with proarrhythmic conditions like heart diseases, electrolyte abnormalities, and concomitant medications. The use of this medicine associated with QT prolongation

    Adrenal insufficiency

    Nizol 200mg Tablet (Ketoconazole) should be used with caution in patients with adrenal insufficiency, which leads to worsening the patient's health conditions. Based on the patient clinical conditions, dose adjustment, or replacement is needed


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag


    Fast Tag

    Fluconazole is an azole antifungal drug, results in inhibiting the production of certain vital components (required for cell membrane formation, helpful for fungal growth). Then it eradicates the fungal infection