Brand Name Nox TZ Tablet
Salt Composition

Norfloxacin (400mg) + Tinidazole (600mg)

Strength 400mg + 600mg
Product Form Tablet
Pack 12 Tablet(s) in Strip
Storage Store below 30°C
Category

Antibiotic

SubCategory

Anti-Biotic

Country of Origin India
Manufacturer

Micro Labs Ltd

Manufacturer/Marketer Address Micro Labs Ltd, No 27, Race Course Road, Bangalore - 560001 India
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M.R.P : Rs.46.00       Price : Rs.41.40

You Save : Rs.4.60    Inclusive of all taxes

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12 Tablet(s) in Strip

Availability : In Stock

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  Non Returnable Read More



    Medical Description of Nox TZ Tablet

    Nox TZ Tablet contains Norfloxacin 400mg and Tinidazole 600mg used to treat severe bacterial infections such as Diarrhoea and Dysentery. Mainly this bacterial infection targets the urinary tract, nose, throat, skin and soft tissues, and lungs. Norfloxacin 400mg is an antibiotic that helps to inhibit the growth of infection. Tinidazole 600mg is antihelmintic which kills the parasites and anaerobic bacteria. This combination of medicine helps to kill microorganisms. This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial infections.


    Nox TZ Tablet Uses

    It is used in the treatment of the following conditions as bacterial infections such as Diarrhoea and Dysentery


    Nox TZ Tablet Benefits

    Bacterial infections

    Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

    Diarrhea

    Infection to the digestive tract leads to increased frequency of bowel movements or loose watery bowel movements caused by bacteria called diarrhea. It leads to worsening the patient’s health condition. This medicine is used to treat this bacterial infection.

    Dysentery

    It is also called infectious diarrhea. Inflammation of the gut (intestine) leads to bloody stools or watery stools. It is most often caused by shigella bacteria (shigellosis) or an amoeba (parasite), spreading through contaminated food or water. This medicine is used to treat this bacterial infection.


    Nox TZ Tablet Indication

    The Nox TZ Tablet is prescribed in the following indications as Diarrhoea and Dysentery


    Mechanism of action of Nox TZ Tablet

    Nox TZ Tablet contains Norfloxacin 400mg and Tinidazole 600mg is a combination of two medicines. Norfloxacin 400mg is a quinolone antibiotic that produces its action by inhibiting the activity of a bacterial enzyme called DNA gyrase and preventing the bacterial cell from reproduction and repairing themselves and killing the bacteria which is responsible for the infection.

    Tinidazole 600mg is antihelmintic that produces its action by damaging their DNA and killing the parasites and anaerobic bacteria which is responsible for infections.


    How Nox TZ Tablet works

    Nox TZ Tablet contains Norfloxacin 400mg and Tinidazole 600mg is a combination of two medicines. Norfloxacin 400mg is a quinolone antibiotic that produces its action by inhibiting the activity of a bacterial enzyme called DNA gyrase and preventing the bacterial cell from reproduction and repairing themselves and killing the bacteria which is responsible for the infection.

    Tinidazole 600mg is antihelmintic that produces its action by damaging their DNA and killing the parasites and anaerobic bacteria which is responsible for infections.


    Nox TZ Tablet Contraindication

    • Do not take this medicine if you are allergic to Norfloxacin, and Tinidazole
    • It is contraindicated to use the medicine that may prolong the QT interval
    • It is contraindicated to use this medicine if you have a history of tendon infection or tendon rupture, nerve-related problems, myasthenia gravis, and blood disorders


    Nox TZ Tablet Side Effects

    • Photosensitivity
    • Tendon rupture
    • Thrombocythemia
    • Platelets increased
    • Neutropenia
    • Dizziness
    • Increased transaminases
    • Headache
    • Constipation
    • Dyspepsia
    • Dizziness


    FAQs for Nox TZ Tablet

    • Can the use of Nox TZ Tablet cause a metallic taste?

    Yes, the use of this medicine may cause a temporary metallic taste and it can be treated by chewing sugar-free gum or mints and by keeping you hydrated.

    • Can I take a higher them the recommended dose of this medicine to get quick relief?

    No, you should not take higher than the recommended dose it may cause unwanted effects. Kindly consult with your doctor if your symptoms persist even after you complete the course of treatment

    • Can a diabetic patient take a Nox TZ Tablet?

    The use of this medicine may decrease the blood glucose level. So kindly consult with your doctor before taking the medicine


    Precautions and general warning of Nox TZ Tablet

    Alcohol

    The use of alcohol may cause flushing, increased heartbeat, nausea, thirst, chest pain, and low blood pressure while you are receiving this medication. Kindly consult with your doctor

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects on the fetus. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may excrete via breast milk. Kindly consult with your doctor

    Kidney Problem

    The medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    It is considered safe to use this medicine in patients with hepatic impairment and it does not require dose modification. Kindly consult with your doctor.


    How to Take Nox TZ Tablet

    Nox TZ Tablet is taken orally with food. You should not chew, cut or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Nox TZ Tablet in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.


    Use of Nox TZ Tablet in children

    It is considered unsafe to use this medicine in children who are below 3 years. Kindly consult with your doctor.


    Use of Nox TZ Tablet in Elderly Patients

    Nox TZ Tablet should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • Therapy should be administered with caution in patients who are having a history of blood dyscrasias and hepatic impairment
    • Kindly avoid using this medicine if you have peripheral neuropathy and seizure
    • The use of this medicine may increase the risk for developing bacterial overgrowth with long term treatment

    Tendinitis and Tendon rupture (Muscle damage)

    • This medicine causes tendinitis and tendon rupture, which mainly affects your shoulder, hands, ankles, or other joint parts of your body. And muscle damage also occurs usually on the tendons surrounding the muscles. It may experience pain, numbness, or tingling sensations in your muscles. It should be a risk in patients of more than 60 years of age or undergone a transplant of kidney, heart, or lung. If necessary, then needs dose adjustment or replacement

    Diarrhea

    • This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. It leads to worsening the patient’s health condition. Better to take probiotics with this medicine to avoid diarrhea.

    Antibiotic resistance

    • Finish the complete course of antibiotics even if you feel better. Otherwise, it will lead to Antibiotic resistance (the bacteria may be resistant to antibiotics)


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have a history of joint issues
    • You have a Glucose-6 phosphate dehydrogenase


    General instructions

    • Norfloxacin 400mg is a quinolone antibiotic that produces its action by inhibiting the activity of a bacterial enzyme called DNA gyrase and preventing the bacterial cell from reproduction and repairing themselves and killing the bacteria which is responsible for the infection.
    • Tinidazole 600mg is antihelmintic that produces its action by damaging their DNA and killing the parasites and anaerobic bacteria which is responsible for infections.


    Drug Interaction of Nox TZ Tablet

    Drug-Drug Interaction

    BCG vaccine live

    The use of this drug is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism

    Aluminum hydroxide

    Use alternative drugs because the use of aluminum hydroxide decreases the effect of norfloxacin by inhibiting the GI absorption

    Escitalopram

    Therapy should be administered with caution because the use of escitalopram increase the toxicity of norfloxacin by QTc interval

    Estradiol

    Therapy should be administered with caution because the use of norfloxacin decreases the effect of estradiol by altering the intestinal flora and it also lowers the risk of contraceptive failure.

    Anti-diabetic drug

    Therapy should be administered with caution because the use of norfloxacin increases the effect of glimepiride by pharmacodynamic synergism.

    Haloperidol

    It should be administered with caution because the combination of this medicine increases the QTc interval.

    Dronabinol

    The use of this drug is contraindicated because the use of tinidazole increases the toxicity of dronabinol by inhibiting aldehyde dehydrogenase

    Ketoconazole

    Use alternative drugs because the use of ketoconazole increases the effect of tinidazole by affecting its hepatic or intestinal metabolism

    Drug-Food Interaction

    No interaction was found while using this medicine

    Drug-Disease Interaction

    Central nervous system disorders

    Using this medicine is needs caution in patients with seizures, other central nervous system abnormalities, or fits. It causes hallucinations, anxiety, confusion, and restlessness, etc. Inform the doctor, then will do dose adjustment or replacement is needed. If necessary to take this medicine with seizure medications.

    Colitis

    This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This drug should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient’s health condition.

    QT prolongation

    This drug should be used with caution in patients with heart-related problems such as irregular heart rate, in which this drug alters the heart rate.

    Kidney diseases

    It should be used with caution in a patient with renal impairment or kidney disease. Then it leads to the risk of kidney damage. Based on the patient clinical condition, adjust the dose accordingly.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • Nox TZ Tablet contains Norfloxacin 400mg and Tinidazole 600mg used to treat severe bacterial infections such as Diarrhoea and Dysentery. Mainly this bacterial infection targets the urinary tract, nose, throat, skin and soft tissues, and lungs.
    • Norfloxacin 400mg is a quinolone antibiotic used to treat bacterial infection by preventing bacteria reproduction and repairing themselves. Tinidazole 600mg is an antihelmintic used to kill other infectious microorganisms in addition to bacteria by binding their DNA. This drug combination prevents bacterial infections effectively.
    • This medicine is not used for common flu and cold symptoms. And not treat viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial and parasitic infections.
    • This medicine is contraindicated to allergic symptoms such as skin rash, itching, swelling, and breathing difficulties.