Oxaltor 100mg Infusion
Brand Name | Oxaltor 100mg Infusion |
Salt Composition |
Oxaliplatin 100mg |
Strength | 100mg |
Product Form | Infusion |
Category |
Anti-Cancer |
SubCategory |
Colon Cancer |
Country of Origin | India |
Manufacturer |
Mylan Pharmaceuticals Private Limited |
Manufacturer/Marketer Address | Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7th to 12th floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103 |
- Non-Hodgkin Lymphoma
- Chronic Lymphocytic Leukemia
- Esophageal Cancer
- Neoplasm of Stomach
- Neuroendocrine Tumor
- Testicular Cancer
- Ovarian Cancer
- Pancreatic Adenocarcinoma
- Cholangiocarcinoma
- if you are allergic to Oxaltor 100mg (Oxaliplatin 100mg) Infusion or its constituents
- if you are pregnant
- if you are breastfeeding
- if you are vaccinating
- if you have a kidney disorder
- if you have a neurological disorder
- if you have a lung disorder
- if you have a heart disorder
- if you have a liver disorder
- if you are a smoking/tobacco user
- Allergic reactions - It can be mild hypersensitivity and angioedema to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.
- Renal toxicity
- Neurotoxicity
- Avoid cold food/air for the next 4 days
- Pulmonary toxicity – pulmonary fibrosis
- Gastrointestinal effects
- Cardiotoxic – MI/CHF/AF/bradycardia/prolonged QT syndrome
- Electrolyte imbalance – hypokalemia
- Reversible posterior leukoencephalopathy syndrome
- Rhabdomyolysis
- Hepatotoxic
- Pregnancy – causes embryo-fetal toxicity
- Breastfeeding – causes side effects similar to adults
- Alcohol intake or Driving or operating heavy machinery – Oxaltor 100mg Infusion causes side effects thus caution is required. consult your physician
- Cardiac disorders – used with caution in QTc prolongation. Consult a physician before use
- Hematological disorders – used with caution in bleeding disorders like thrombosis. Consult a physician before use
- Bone disorders – used with caution in osteonecrosis. Consult a physician before use.
- Liver disorders – used with caution in severe liver diseases. Consult a physician before use
- Kidney disorders – used with caution in severe kidney diseases. Consult a physician before use
- Respiratory disorders – used with caution in respiratory distress and interstitial lung disorder. Consult a physician before use
Medical Description of Oxaltor 100mg Infusion
Oxaltor 100mg Infusion contains Oxaliplatin 100mg it’s an antineoplastic and alkylating agent. It is a platinum analogue. This medication is used in the treatment of colorectal carcinoma. It is used as an orphan drug in treating chronic lymphocytic leukaemia, esophageal cancer, neoplasm of the stomach, neuroendocrine tumor, non-Hodgkin lymphoma, testicular cancer, ovarian cancer, pancreatic adenocarcinoma and cholangiocarcinoma. It is always used in combination with 5-fluorouracil
Oxaltor 100mg Infusion Uses
Oxaltor 100mg Infusion is used in the treatment of colorectal cancer at stage 3. It is not used in children. It is also used as an orphan drug in several cancers and leukemia. It is used only in adults.
Oxaltor 100mg Infusion Benefits
Oxaltor 100mg Infusion is an antineoplastic, alkylating drug used in the treatment of colorectal cancer in adults.
Oxaltor 100mg Infusion Indication
Oxaliplatin is used as an orphan drug in the treatment of
Mechanism of action of Oxaltor 100mg Infusion
Oxaliplatin is an alkylating medication. It causes intra- and inter-strand crosslinks between DNA bases causing breaks in DNA strands thus apoptosis is induced resulting in cell death of abnormal DNA containing cancer cells.
How Oxaltor 100mg Infusion works
Oxaltor 100mg Infusion causes DNA base pairs to break inducing apoptosis of these abnormal cancer cells.
Oxaltor 100mg Infusion Contraindication
Absolute contraindication:
Relative contraindication:
Oxaltor 100mg Infusion Side Effects
Common side effects that occur 1:10 patients: Peripheral neuropathy, Anemia, Nausea, Fatigue, Diarrhea, Vomiting, Abdominal pain, Constipation, Thrombocytopenia, Fever, Anorexia, Leukopenia, Dyspnea, Cough
Uncommon side effects that occur 1:100 patients: Edema, Neutropenia, Pharyngolaryngeal dysesthesia, Anaphylactic-like reaction, Pulmonary fibrosis, hypokalemia
Rare side effects that occur 1:1,000 patients: Pulmonary fibrosis, Posterior leukoencephalopathy syndrome, Loss of deep tendon reflexes, dysarthria, Lhermitte’s sign, cranial nerve palsies, fasciculations, convulsion, RPLS, Deafness, Laryngospasm, colitis, metabolic acidosis, ileus, intestinal obstruction, pancreatitis; veno-occlusive disease of liver, perisinusoidal fibrosis, Hemolytic uremic syndrome, Acute tubular necrosis, acute interstitial nephritis, acute renal failure, Pulmonary fibrosis, interstitial lung diseases, Rhabdomyolysis, Septic shock
FAQs for Oxaltor 100mg Infusion
Is Oxaltor 100mg (Oxaliplatin 100mg) Infusion safe during pregnancy?
No, taking Oxaltor 100mg Infusion during pregnancy is not recommended thus inform your physician if you are pregnant or plan to get pregnant
Can Oxaltor 100mg Infusion be taken while breastfeeding?
No, in general it is suggested that drugs and their metabolites can pass via breastfeeding thus it is suspected that Oxaltor 100mg Infusion can also pass via breastfeeding.
Can Oxaltor 100mg Infusion be taken while alcohol consumption?
The interaction is unknown but Oxaltor 100mg Infusion causes side effects. Thus, consult your physician.
Can I take a drive or operate heavy machineries while on Oxaltor 100mg Infusion?
Oxaltor 100mg Infusion causes side effects thus caution is used while driving or operating machineries.
Can you smoke or use tobacco while using Oxaltor 100mg Infusion?
No, smoking and tobacco use causes interaction with Oxaltor 100mg Infusion thus should be avoided.
Precautions and general warning of Oxaltor 100mg Infusion
Alcohol
Intake of alcohol with Oxaltor 100mg Infusion causes side effects thus caution is required. consult your physician.
Driving or operating machinery
Driving or operating heavy machinery with Oxaltor 100mg Infusion causes side effects thus caution is required. consult your physician.
Pregnancy
Using Oxaliplatin during pregnancy may cause embryo-fetal toxicity. Consult your physician.
Breast Feeding
Using Oxaliplatin during breastfeeding may cause side effects similar to adults. Consult your physician.
Kidney Problem
Renal toxicity
Liver Disease
Hepatotoxic
How to Take Oxaltor 100mg Infusion
Oxaltor 100mg Infusion is used only in the presence of physician; Do not shake medicine containing vial while diluting or infusing; It is compatible with D5W; Do not use NS or chloride containing solutions; It is infused into 250-500ml of D5W and administered as slow infusion; Refrigerate unopened or opened 8°C
After therapy has been initiated, do not take more or less of this drug than prescribed or stop taking it without your physicians’ approval. Skipping or changing your dose without approval may cause adverse effects making the condition more difficult to treat, or worsen side effects.
Use of Oxaltor 100mg Infusion in Adult
If you are pregnant or breastfeeding inform your physician as they are not advisable.
Use of Oxaltor 100mg Infusion in children
This Infusion is not recommended in children.
Use of Oxaltor 100mg Infusion in Elderly Patients
This Infusion has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.
Other general warnings
Talk to your doctor if
If you have any allergy
If you have a liver problem
If you have a kidney problem
If you have a neurological problem
If you are pregnant or breastfeeding
General instructions
Oxaltor 100mg Infusion is given intravenously in the presence of a physician. It must be kept at 8°C. Do not store after a single-use.
Drug Interaction of Oxaltor 100mg Infusion
Drug-Drug Interaction
Serum concentration increased by Choline, Thiamine
Therapeutic efficacy is decreased by Cyanocobalamin
Severity of bleeding is increased by Icosapent ethyl
Severity of adverse effects is increased by Phenylalanine, Tretinoin
Drug-Food Interaction
This Infusion can be taken with any type of food, if doubts arise kindly refer to your physician. It generally causes side effects thus it is advised not to be taken with alcohol. It is preferred to drive or operate heavy machinery with caution. Do not smoke while taking this medication. Do not use tobacco while taking this medication.
Drug-Disease Interaction
Over Dose
In the case of Overdosage with this Infusion Contact your physician.
Missed Dose
Consult your physician immediately.
Storage and Disposal
Keep the medication out of children’s reach
Keep the medication away from pets
Once expired dispose immediately
Store at 8°C
Fast Tag
Oxaltor 100mg Infusion is an antineoplastic drug
Oxaliplatin is an alkylating agent
This Infusion is used to control and treat colorectal cancer
Do not use this medication while pregnant and lactation period.
Don’t use this medication with liver disease or renal diseases or hematological disorders.