PACLITAX 100mg INJECTION
Brand Name | PACLITAX 100mg INJECTION |
Salt Composition |
Paclitaxel (100mg) |
Strength | 100mg |
Product Form | Injection |
Pack | 1 x 1ml in 1 vial |
Storage | Store below 30°C |
Category |
Anti-Cancer |
SubCategory |
Ovarian Cancer |
Country of Origin | India |
Manufacturer |
Cipla Ltd |
Manufacturer/Marketer Address | Cipla Ltd,Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013. |
You Save : Rs.724.45 Inclusive of all taxes
- Metastatic ovarian cancer
- Breast cancer which is node-positive and metastatic
- Non-small cell lung cancer
- Do not take this medicine if you are allergic to Paclitaxel
- It is contraindicated to use this medicine in patients with solid tumors, AIDS-related Kaposi’s sarcoma with neutrophils count less than 1, 500 cells/mm3
- Neutropenia
- Alopecia
- Anemia
- Diarrhea
- Leukopenia
- Opportunistic infections
- Peripheral neuropathy
- Thrombocytopenia
- Hypotension
- Mucositis
- Myalgia
- Does PACLITAX 100mg Injection cause hair loss?
- What is PACLITAX 100mg Injection derived from?
- Is PACLITAX 100mg Injection light-sensitive, hydrophobic and cardiotoxic?
- The use of this medicine may increase the risk of developing cardiac dysfunction when along with anthracyclines.
- The use of this medicine may cause fatal anaphylaxis, dyspnea, and hypotension, angioedema, urticaria
- Bone marrow suppression is dose-dependent and dose-limiting toxicity
- During this therapy, severe conduction abnormalities have been documented
- You are not responding to the treatment
- You have experienced any allergic reaction like rashes and itching
- You have a receiving any concomitant medication and disease
- Stored at 10-30°C room temperature.
- Protect from light and heat.
- Keep away from children and pets. Otherwise, it becomes toxic to them.
- Disposed of properly in a suitable bag.
- PACLITAX 100mg Injection contains Paclitaxel 100mg used to treat ovarian cancer, breast cancer, non-small cell lung cancer, and pancreatic cancer. Paclitaxel helps to inhibit the growth and multiplication of cancer cells. Do not self administer this medicine.
- Do not use this medication while pregnant and lactation period.
- Don’t use this medication with liver disease or heart diseases.
Medical Description of PACLITAX 100mg INJECTION
PACLITAX 100mg Injection contains Paclitaxel 100mg used to treat ovarian cancer, breast cancer, non-small cell lung cancer, and pancreatic cancer. Paclitaxel helps to inhibit the growth and multiplication of cancer cells. Do not self administer this medicine.
PACLITAX 100mg INJECTION Uses
It is used in the treatment of the following conditions as ovarian cancer, breast cancer, non-small cell lung cancer, and pancreatic cancer.
PACLITAX 100mg INJECTION Benefits
Ovarian cancer
It is a type of cancer that occurs in an ovary a female reproductive system that produces women’s eggs and female hormones. The exact is not clear but if you have a history of ovarian cancer in your family. Symptoms include abdominal bloating, weight loss, discomfort in the pelvic area, fatigue, back pain, constipation, and frequent urination. This medicine helps to inhibit the multiplication of cancer cells.
Breast cancer
It is a type of cancer that forms in the breast cells. It is common among women. Symptoms include breast lump, change in breast size, redness, pitting of the skin, color change, and peeling surrounding the breast skin or nipple. This medicine helps to inhibit the multiplication of cancer cells.
Pancreatic cancer
It usually starts in the tissue of your pancreas, the organ in your abdomen which lies behind the stomach. Smoking, diabetes pancreatitis, obesity may increase the chance of developing pancreatic cancer. Symptoms include abdominal pain, loss of appetite, yellow color of skin, light-colored stools, itchy skin, dark-colored urine, blood clots, and fatigue. This medicine helps to inhibit the multiplication of cancer cells.
Non-small cell lung cancer
It is the common type of lung cancer and it grows, spreads slowly when compared with small lung cell cancer. Smoking is the common cause of non-small cell lung cancers. Symptom includes fatigue, weight loss, shortness of breath, loss of appetite, coughing up with cough or phlegm, and cough. This medicine helps to inhibit the multiplication of cancer cells.
PACLITAX 100mg INJECTION Indication
The PACLITAX 100mg Injection is prescribed in the following indications as
It is used as an orphan drug in the case of pancreatic cancer, esophageal cancer, adenocarcinoma of the stomach, adenocarcinoma of lower esophagus, brain cancer, angiosarcoma, head and neck cancer, hormone-refractory prostate cancer, urothelium traditional cell carcinoma
Mechanism of action of PACLITAX 100mg INJECTION
PACLITAX 100mg Injection contains Paclitaxel 100mg is an anti-cancer agent called Antimicrotubular inhibitor that produces its action by interfering in the function of the growth phase of microtubules at G2/M phase of cell cycle disrupting mitotic spindle formation and apoptosis is induced.
How PACLITAX 100mg INJECTION works
PACLITAX 100mg Injection contains Paclitaxel 100mg is an anti-cancer agent called Antimicrotubular inhibitor that produces its action by interfering in the function of the growth phase of microtubules at G2/M phase of cell cycle disrupting mitotic spindle formation and apoptosis is induced.
PACLITAX 100mg INJECTION Contraindication
PACLITAX 100mg INJECTION Side Effects
FAQs for PACLITAX 100mg INJECTION
Yes, one of the common side effects of this medicine is hair loss. Kindly consult with your doctor if your symptoms even persist after withdrawal of the medicines.
Taxoanb injection derived from the bark of the Pacific yew, Taxus brevifolia
Yes, the use of PACLITAX 100mg Injection is light sensitive, hydrophobic, and cardiotoxic.
Precautions and general warning of PACLITAX 100mg INJECTION
Alcohol
The use of alcohol may produce harmful effects while you are receiving this treatment. Kindly consult with your doctor.
Driving or operating machinery
It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.
Pregnancy
The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor
Breast Feeding
The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor
Kidney Problem
It is considered safe to use this medicine in patients who are having a renal impairment. Kindly consult with your doctor.
Liver Disease
The medicine should be used with caution in patients with hepatic impairment. The use of this medicine required dose modification. Kindly consult with your doctor.
How to Take PACLITAX 100mg INJECTION
PACLITAX 100mg injection comes in a liquid solution as an intravenous injection. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.
Use of PACLITAX 100mg INJECTION in Adult
It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor
Use of PACLITAX 100mg INJECTION in children
Safety and efficacy were not established in children who are below 18 years old. Kindly consult with your doctor.
Use of PACLITAX 100mg INJECTION in Elderly Patients
PACLITAX 100mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.
Other general warnings
Talk to your doctor if
General instructions
Paclitaxel 100mg is used to treat ovarian cancer, breast cancer, non-small cell lung cancer, and pancreatic cancer. Paclitaxel is an anti-cancer agent called an Antimicrotubular inhibitor that produces its action by interfering in the function of the growth phase of microtubules at the G2/M phase of the cell cycle disrupting mitotic spindle formation and apoptosis is induced.
Drug Interaction of PACLITAX 100mg INJECTION
Drug-Drug Interaction
Apalutamide
Use alternative drugs because the use of apalutamide will decrease the effect of paclitaxel by affecting hepatic and intestinal enzyme metabolism.
Deferiprone
Use alternative drugs because the combination of this medicine either increases the toxicity of the other by pharmacodynamic synergism.
Amiodarone
Therapy should be administered with caution because the use of amiodarone will increase the effect of paclitaxel by P-glycoprotein efflux transporter.
Cannabidiol
Therapy should be administered with caution because the use of cannabidiol will increase the effect of paclitaxel by decreasing its metabolism
Ketoconazole
Therapy should be administered with caution because the use of ketoconazole will increase the level of paclitaxel by affecting its hepatic and intestinal enzyme metabolism.
Drug-Food Interaction
Kindly avoid consuming grapefruit juice while you are receiving this medicine it may increase the blood level of paclitaxel and also increase the risk of side effects such as nausea, diarrhea, hair loss, muscle pain, weakness, nerve damage, and impaired bone marrow functions.
Drug-Disease Interaction
Infections
The use of this medicine is contraindicated in patients with infectious diseases because of their cytotoxic effect it induces myelosuppression.
Conduction disorders
Therapy should be administered with caution in patients who are having a history of conduction disorders because the use of paclitaxel may cause severe conduction abnormalities.
Hepatic dysfunction
Therapy should be administered with caution in patients with hepatic impairment because the use of this medicine may increase the risk of developing hepatotoxicity.
Myelosuppression
Therapy should be not be administered in patients who are having a neutrophil count less than 1500/mm3 because paclitaxel may induce dose-dependent myelosuppression.
Over Dose
Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.
Missed Dose
Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).
Storage and Disposal
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