Pirfemil 200mg Tablet

Brand Name Pirfemil 200mg Tablet
Salt Composition

Pirfenidone (200mg)

Strength 200mg
Product Form Tablet
Storage Store below 30°C
Category

Antifibrotic

SubCategory

Idiopathic Pulmonary Fibrosis

Country of Origin India
Manufacturer

Indian Drug Distributors Private Limited

Manufacturer/Marketer Address Indian Drug Distributors Private Limited, 2nd Floor Shop No 13, Bhagwan Bhavan , 15/37 Dadi Santuk Lane Kamaniwadi, Chira Bazar, Mumbai City, Maharashtra, 400002.
Pirfemil 200mg Tablet, Pirfenidone 200mg, price, uses, side Effects - Drugcarts watermark
M.R.P : Rs.230.00    

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Availability : In Stock


    Medical Description of Pirfemil 200mg Tablet

    Pirfemil 200mg Tablet contains Pirfenidone 200mg is a growth factor inhibitor intended for oral use only. This medication is used to treat idiopathic pulmonary fibrosis and produces its action by removing the scars and inflammation in the lungs and it also helps you to breathe normally


    Pirfemil 200mg Tablet Uses

    Pirfemil 200mg Tablet is used to treat idiopathic pulmonary fibrosis.


    Pirfemil 200mg Tablet Benefits

    Used in the treatment for the following condition such as

    Idiopathic pulmonary fibrosis:

    It is a form of interstitial lung disease which causes fibrosis of the lungs for an unknown reason. In long term, this may get worsen and become hard to take a deep breath. Risk factors are cigarette smoking, age, gastroesophageal reflux diseases. Symptoms include breathlessness, chronic cough, chest pain, weight loss, loss of appetite, and clubbing


    Pirfemil 200mg Tablet Indication

    Pirfemil 200mg Tablet produces its action by removing the scars and inflammation in the lungs and it also helps you to breathe normally. This tablet is used in the treatment of the following condition such as idiopathic pulmonary fibrosis.


    Mechanism of action of Pirfemil 200mg Tablet

    Pirfemil 200mg (Pirfenidone) produces its action by inhibiting transforming growth factors, it is a chemical mediator which controls many cell functions like proliferation and differentiation. It also inhibits the synthesis of TNF-alpha, a cytokine that has an active role in inflammation


    How Pirfemil 200mg Tablet works

    Pirfenidone produces its action by removing the scars and inflammation in the lungs and it also helps you to breathe normally


    Pirfemil 200mg Tablet Contraindication

    If you are allergic to the composition of the medicine


    Pirfemil 200mg Tablet Side Effects

    • Nausea
    • Rash
    • Upper respiratory tract infection
    • Diarrhea
    • Abdominal pain
    • Headache
    • Dyspepsia
    • Vomiting
    • GERD
    • Weight loss
    • Pruritus


    FAQs for Pirfemil 200mg Tablet

    What monitoring will I need during treatment with the Pirfemil 200mg Tablet?

    Before initiating the treatment your doctor will check your liver function test repeatedly for the first 6 months and every 3 months and also closely monitor the lung function

    What should I avoid while taking the Pirfemil 200mg Tablet?

    Avoid sunlight while you are taking this tablet wear sunglasses, creams to reduce exposure to sunlight. And also quit smoking because smoking may alter the effect of the tablet

    What is the instruction for storage and disposal of the Pirfemil 200mg Tablet?

    Store the medicine in a closed container at room temperature, away from heat, moisture, and direct sunlight. Keep out of the reach of children. Do not keep outdated medicine. Ask your doctor or pharmacist how to dispose of medicine that is not in use and store below 30C


    Precautions and general warning of Pirfemil 200mg Tablet

    Alcohol

    It is not known that consuming alcohol may affect the drug. Kindly consult with your doctor

    Driving or operating machinery

    It is considered unsafe during driving you feel dizziness. Kindly consult with your doctor

    Pregnancy

    It is considered unsafe during pregnancy it may cause harmful effects to the fetus. Kindly consult with your doctor.

    Breast Feeding

    It is considered safe during breastfeeding it may not excrete via breast milk. Kindly consult with your doctor.

    Kidney Problem

    Use caution to the patient who is having a renal impairment. Kindly consult with your doctor. Dose adjustment is needed, closely monitor the patient renal function

    Liver Disease

    Use caution to the patient who is having a hepatic impairment. Kindly consult with your doctor. Dose adjustment is needed, closely monitor the patient hepatic functions


    How to Take Pirfemil 200mg Tablet

    The tablet is taken orally by mouth thrice daily with foodDo not chew, crush or break the capsule. Follow the direction mentioned in the label if you did not understand the application kindly ask your doctor or pharmacist to explain the details. Do not discontinue the medicine when you feel better kindly consult with your doctor.

    If you are taking the tablet initially start with a low dose and gradually increase the dose when over 2 weeks period.


    Use of Pirfemil 200mg Tablet in children

    It is considered safe if the medicine is prescribed by your doctor


    Use of Pirfemil 200mg Tablet in Elderly Patients

    It is considered safe to an elderly patient if the medicine is prescribed by your doctor


    Other general warnings

    • Conduct liver function test before initiating the tablet
    • Photosensitivity and rash were reported
    • Quit smoking


    Talk to your doctor if

    • If you are allergic to the composition of the tablet
    • If you are using any concomitant medications
    • If you are not responding to the treatment


    Drug Interaction of Pirfemil 200mg Tablet

    Drug-Drug Interaction

    Carbamazepine + Pirfenidone

    Carbamazepine decreases the effect of pirfenidone by affecting the hepatic enzymes metabolism. The use of this drug is contraindicated.

    Aminolevulinic acid + Pirfenidone

    A combination of this drug either increases the toxicity of the other by pharmacodynamic synergism. Use alternative drug

    Cimetidine + Pirfenidone

    Cimetidine increases the effect of pirfenidone by affecting the hepatic enzyme metabolism. Use alternative drug

    Ciprofloxacin + Pirfenidone

    Ciprofloxacin increases the effect of pirfenidone by affecting the hepatic enzyme metabolism. Use alternative drugs.

    Drug-Food Interaction

    Smoking may alter the effect of pirfenidone so the patient should not smoke while taking pirfenidone

    Drug-Disease Interaction

    Hepatic impairment

    The patient who is taking pirfenidone has been noticed that there is an increase in ALT and AST levels with or without an increase in bilirubin. Pirfenidone should be administered with caution to the patient with mild to moderate hepatic impairment.

    Renal impairment:

    Pirfenidone should be administered with caution to the patient with mild to moderate, severe renal impairment due to serious side effects.


    Over Dose

    Consuming more tablets than the prescribed dose may lead to overdose. Kindly use the medicine as per your doctor advice


    Missed Dose

    If you missed the dose take it as soon as you remember. If it is time for the next dose skip the missed dose and continue with a regular dose


    Storage and Disposal

    • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct sunlight
    • Keep out of the reach of children
    • Do not keep outdated medicine
    • Ask your doctor or pharmacist how to  dispose of medicine that is not in use
    • Store below 30°C


    Fast Tag

    • Pirfenidone is a transforming growth factor inhibitor
    • It is used to treat idiopathic pulmonary fibrosis
    • The tablet is taken orally by mouth thrice daily with food
    • Do not use this medicine if you are allergic to the composition of the tablet