Pivikto 200mg Tablet
Brand Name | Pivikto 200mg Tablet |
Salt Composition |
Alpelisib (200mg) |
Strength | 200mg |
Product Form | Tablet |
Pack | 14 Tablet(s) in Strip |
Storage | Store below 30°C |
Category |
Anti-Cancer |
SubCategory |
Breast Cancer |
Country of Origin | Switzerland |
Manufacturer |
Novartis India Limited, Tardeo Site |
Manufacturer/Marketer Address | Novartis India Limited, Tardeo Site,Film Center, Near AC Market, 5th Floor, Tardeo, Mumbai 400 034, India |
You Save : Rs.6,800.00 Inclusive of all taxes
- Do not take this medicine if you are allergic to Alpelisib
- Hyperglycemia
- Diarrhea
- Rash
- Nausea
- Anemia
- Loss of appetite
- Weight loss
- Hair loss
- Abdominal pain
- Peripheral edema
- Decreased platelet count
- Potassium decreased
- Albumin decreased
- Magnesium decreased
- What blood tests are required before administration of the Pivikto 200mg Tablet?
- How and in what dose should I take the Pivikto 200mg Tablet?
- Can I stop using the Pivikto 200mg Tablet immediately or do I have to slowly wean off the use?
- The use of this drug may cause severe hypersensitivity reactions, severe pneumonitis including interstitial pneumonia, interstitial lung disease, diarrhea
- Therapy should be administered with caution in patients with diabetes because severe hyperglycemia, ketoacidosis has been reported in patients who are treated with alpelisib. Before initiating the treatment closely monitor the patient blood glucose level.
- You are not responding to the treatment
- You have experienced any allergic reaction like rashes and itching
- You have a receiving any concomitant medication and disease
- Stored at 10-30°C room temperature.
- Protect from light and heat.
- Keep away from children and pets. Otherwise, it becomes toxic to them.
- Disposed of properly in a suitable bag.
- Alpelisib 200mg is an anti-cancer medication, a phosphatidylinositol-3-kinase inhibitor
- It is used to treat breast cancer
- Do not withdraw the medicine without consulting with a doctor
- Use non-hormonal methods of contraception to avoid pregnancy because the use of this medicine may cause fetal harm
- Drink plenty of fluids to manage diarrhea
Medical Description of Pivikto 200mg Tablet
Pivikto 200mg Tablet contains Alpelisib 200mg used to treat breast cancer. It works by inhibiting the growth of cancer cells. It is not recommended in children. The combination of alpelisib with fulvestrant has more antitumor activity when compared with either treatment alone.
Pivikto 200mg Tablet Uses
It is used in the treatment of the following conditions as Breast cancer.
Pivikto 200mg Tablet Benefits
Breast cancer
It is a type of cancer seen in breasts. Cancer occurs when a cell begins to grow out of control. This type of cancer is most common in women. It can occur due to age, family history, and genetic factors. Symptoms include pain in the armpit, redness of the breast, discharge from a nipple, inverted nipple, and change in the size or shape of the breast.
Pivikto 200mg Tablet Indication
The Pivikto 200mg Tablet is prescribed in the following indications as breast cancer.
Mechanism of action of Pivikto 200mg Tablet
Pivikto 200mg Tablet contains Alpelisib 200mg is an anti-cancer medication, it produces its action by inhibiting the phosphorylation of PI3K downstream targets and shows its effect in cell lines possessing a PIK3CA mutation. Inhibition of this PI3K induces an increase in estrogen receptor transcription.
How Pivikto 200mg Tablet works
Pivikto 200mg Tablet contains Alpelisib 200mg is an anti-cancer medication, it produces its action by inhibiting the phosphorylation of phosphatidylinositol-3-kinase inhibitor which results in inhibition of the growth of tumor cells.
Pivikto 200mg Tablet Contraindication
Pivikto 200mg Tablet Side Effects
FAQs for Pivikto 200mg Tablet
Before initiating the treatment with this medicine you may be asked to have blood tests, liver function tests.
Take the medicine as per the dose and duration advice by the doctor. Take the dose daily without missing the frequency of the drug.
You should not withdraw the medicine immediately, you should taper the dose to avoid rebound effects.
Precautions and general warning of Pivikto 200mg Tablet
Alcohol
No information is available regarding the use of this medicine. Kindly consult with your doctor
Driving or operating machinery
No information is available regarding the use of this medicine. Kindly consult with your doctor
Pregnancy
No information is available regarding the use of this medicine. Kindly consult with your doctor
Breast Feeding
No information is available regarding the use of this medicine. Kindly consult with your doctor
Kidney Problem
No information is available regarding the use of this medicine. Kindly consult with your doctor
Liver Disease
No information is available regarding the use of this medicine. Kindly consult with your doctor
How to Take Pivikto 200mg Tablet
Pivikto 200mg Tablet can be taken orally with or without food. You should not chew, cut or crush the tablet. Take the medicine as per the dose and duration advised by your doctor. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.
Use of Pivikto 200mg Tablet in Adult
It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor
Use of Pivikto 200mg Tablet in children
Safety and efficacy were not established. Kindly consult with your doctor.
Use of Pivikto 200mg Tablet in Elderly Patients
Pivikto 200mg Tablet should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.
Other general warnings
Talk to your doctor if
General instructions
Alpelisib 200mg is used to treat breast cancer. It produces its action by inhibiting the phosphorylation of phosphatidylinositol-3-kinase inhibitor which results in inhibition of the growth of tumor cells.
Drug Interaction of Pivikto 200mg Tablet
Drug-Drug Interaction
Abametapir + Alpelisib
Use alternative drugs because the use of abametapir will increase the effect of alpelisib by affecting the patient's hepatic and intestinal enzyme metabolism.
Cyclosporine + Alpelisib
Use alternative drugs because the use of cyclosporine will increase the effect of alpelisib by increasing the risk of toxicities.
Armodafinil + Alpelisib
Therapy should be administered with caution because the use of armodafinil will decrease the effect of alpelisib by affecting the patient's hepatic and intestinal enzyme metabolism.
Butabarbitol + Alpelisib
Use alternative drugs because the use of butabarbital will decrease the effect of alpelisib by affecting the patient's hepatic and intestinal enzyme metabolism.
Warfarin + Alpelisib
Therapy should be administered with caution because the use of warfarin will increase the effect of alpelisib by affecting the patient's hepatic and intestinal enzyme metabolism.
Drug-Food Interaction
Food may increase the absorption of alpelisib. Do not take the medicines on an empty stomach because it may lead to inadequate blood levels and decrease the effectiveness of the medicines.
Drug-Disease Interaction
Renal impairment
The pharmacokinetics of alpelisib is unknown so monitoring is recommended when you are using this medicine in patients with severe renal impairment. Likewise, no dose adjustment is recommended for patients with mild to moderate renal impairment.
Diarrhea
Therapy should be administered with caution because the use of alpelisib can cause severe diarrhea, acute kidney injury. Immediately seek the hospital if you have noticed diarrhea while you are receiving this medicine.
Diabetes
Therapy should be administered with caution in patients with diabetes because severe hyperglycemia, ketoacidosis has been reported in patients who are treated with alpelisib. Before initiating the treatment closely monitor the patient blood glucose level.
Over Dose
Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.
Missed Dose
Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).
Storage and Disposal
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