Platinex 50mg Infusion
Brand Name | Platinex 50mg Infusion |
Salt Composition |
Cisplatin (50mg) |
Strength | 50mg |
Product Form | Infusion |
Pack | 50 ml in 1 bottle |
Storage | Store below 30°C |
Category |
Anti-Cancer |
SubCategory |
Bladder Cancer |
Country of Origin | India |
Manufacturer |
Khandelwal Laboratories Pvt Ltd |
Manufacturer/Marketer Address | Khandelwal Laboratories Pvt Ltd,79/87 D.LAD PATH, KALA CHOWKIE MUMBAI MH 400033 IN |
You Save : Rs.72.62 Inclusive of all taxes
- Leukopenia
- Neutropenia
- Nausea, vomiting
- Anemia
- Thrombocytopenia
- Hair loss
- Increased liver enzymes
- Dehydration
- Peripheral neuropathy
- Is Platinex infusion safe?
- Can I stop using the Platinex infusion immediately or do I have to slowly wean off the use?
- Does Platinex infusion cause hair loss?
- The use of this medicine may cause irritant
- Avoid using aluminum needles
- Therapy should be administered with caution in patients with renal impairment, hearing impairment, neuropathy, neuromuscular diseases
- The use of this medicine may increase the risk of developing cumulative nephrotoxicity
- Myelosuppression, leukemia, cardiac abnormalities, ocular toxicity, renal toxicity, and peripheral neuropathy was reported
- You are not responding to the treatment
- You have experienced any allergic reaction like rashes and itching
- You have a receiving any concomitant medication and disease
- You develop shortness of breath
- Stored at 30°C at room temperature.
- Protect from light and heat.
- Keep away from children and pets. Otherwise, it becomes toxic to them.
- Disposed of properly in a suitable bag.
- Platinex injection contains Cisplatin 50mg is an anti-cancer medication, an alkylating agent used to treat ovarian cancer, bladder cancer, and testicular cancer.
- Do not withdraw the medicine without consulting with a doctor
- Kindly avoid pregnancy while you are receiving this medicine
- Kindly consult with your doctor if you have experienced shortness of breath, chest pain, loss of appetite, and dark urine while you are receiving this medicine
- Drugs.com. Cisplatin Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from: https://www.drugs.com/pregnancy/cisplatin.html
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 279-80.
- Cisplatin Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 25 April 2017]. Available from:https://medlineplus.gov/druginfo/meds/a684036.html
- DailyMed - Cisplatin injection [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 25 April 2017]. Available from:https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b2b029f5-0d7e-4e7f-accc-b722aec34c68#ID36
Medical Description of Platinex 50mg Infusion
Platinex infusion contains Cisplatin 50mg used to treat ovarian cancer, bladder cancer, and testicular cancer. It works by inhibiting the growth of abnormal cells. It is used alone or with other combinations as chemotherapy.
Platinex 50mg Infusion Uses
It is used in the treatment of the following conditions ovarian cancer, bladder cancer, and testicular cancer.
Platinex 50mg Infusion Benefits
Ovarian cancer:
It is a type of cancer that occurs in an ovary a female reproductive system that produces women’s eggs and female hormones. The exact is not clear but if you have a history of ovarian cancer in your family. Symptoms include abdominal bloating, weight loss, discomfort in the pelvic area, fatigue, back pain, constipation, and frequent urination. This medicine helps to inhibit the multiplication of cancer cells.
Urothelial carcinoma
It is also called bladder cancer. It is a type of cancer that begins in the cells in the bladder. It usually occurs when changes occur in the DNA. Symptoms include back pain, blood in urine, frequent urination, and pain while urinating.
Testicular cancer
It is also called a malignant neoplasm of the testis. Cancer usually occurs in the testicles when compared with another type of cancer it is rare. Symptoms include testicle enlargement, abdomen and groin pain, enlargement of breast and back pain
Platinex 50mg Infusion Indication
The Platinex 50mg infusion is prescribed in the following indications as ovarian cancer, bladder cancer, and testicular cancer.
Mechanism of action of Platinex 50mg Infusion
Platinex infusion contains Cisplatin 50mg is an anti-cancer medication, a platinum coordination compound. It produces its action by inhibiting the synthesis of DNA, cross-links, and denatures the strands of DNA. This disrupts the function of DNA by binding to the DNA bases. It can also produce DNA intrastrand cross-linking and breakage and leads to cell death.
How Platinex 50mg Infusion works
Platinex infusion contains Cisplatin 50mg is an anti-cancer medication, a platinum coordination compound. It produces its action by damaging the DNA and RNA of the cancer cells which inhibit the growth and multiplication of cancer cells.
Platinex 50mg Infusion Contraindication
Do not take this medicine if you are allergic to Platinexin
It is contraindicated to use this medicine in patients with severe myelosuppression, bleeding, renal dysfunction, pregnancy, and lactation
Platinex 50mg Infusion Side Effects
FAQs for Platinex 50mg Infusion
Yes, the use of this medicine is considered safe if you have taken the medicine as per the dose and duration advised by the doctor.
You should not withdraw the medicine immediately, you should taper the dose to avoid rebound effects.
Yes, one of the common side effects of this medicine is hair loss. This will get treated once you stop the treatment.
Precautions and general warning of Platinex 50mg Infusion
Alcohol
It is not clear that consuming alcohol is safe while you are receiving this medicine. Kindly consult with your doctor.
Driving or operating machinery
It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.
Pregnancy
The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor
Breast Feeding
The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor
Kidney Problem
Therapy should be administered with caution in patients who are having a renal impairment. Adjust the dose as per the requirement. Kindly consult with your doctor.
Liver Disease
It is considered safe to use this medicine in patients who are with hepatic impairment. Kindly consult with your doctor.
How to Take Platinex 50mg Infusion
This injection comes in an infusion form. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.
Use of Platinex 50mg Infusion in Adult
It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.
Use of Platinex 50mg Infusion in children
It is considered safe to use this medicine in children. Kindly consult with your doctor.
Use of Platinex 50mg Infusion in Elderly Patients
Platinex infusion should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.
Other general warnings
Talk to your doctor if
General instructions
Cisplatin 50mg is used to treat ovarian cancer, bladder cancer, and testicular cancer. It produces its action by damaging the DNA and RNA of the cancer cells which inhibit the growth and multiplication of cancer cells.
Drug Interaction of Platinex 50mg Infusion
Drug-Drug Interaction
Tofacitinib
Use alternative drug because the combination of this medicine either increase the toxicity of the other by immunosuppressive effect and it also increases the risk for developing an infection.
Palifermin
Use alternative drugs because the use of palifermin increases the toxicity of the cisplatin by increasing the severity and duration of oral mucositis
Amikacin
Therapy should be administered with caution because the combination of this medicine increases the nephrotoxicity and ototoxicity
Dichlorphenamide
Therapy should be administered with caution because the combination of this medicine decreases the serum potassium
Peramivir
Therapy should be administered with caution because the use of cisplatin increases the effect of peramivir by decreasing its renal clearance.
Drug-Food Interaction
No data available kindly consult with your doctor
Drug-Disease Interaction
Infections:
The use of this medicine is contraindicated in patients who are having infectious diseases because of their cytotoxic effect their induce myelosuppression.
Myelosuppression:
Therapy should be administered with caution in patients with bone marrow suppression because the use of this medicine induces dose-related myelosuppression, leukopenia, thrombocytopenia, and anemia
Renal dysfunction:
Therapy should be administered with caution in patients with renal impairment because the use of this medicine may cause nephrotoxicity
Hemolytic anemia
Therapy should be administered with caution in patients with a history of hemolytic syndromes because the use of this medicine may cause coomb’s hemolytic anemia
Over Dose
Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.
Missed Dose
Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).
Storage and Disposal
Fast Tag
References